Gene Expression of Glycolysis Enzymes in MCF-7 Breast Cancer Cells Exposed to Warburg Effect and Hypoxia [0.03%]
沃邦效应和低氧条件下MCF-7乳腺癌细胞糖酵解酶的基因表达
Irem Bayar,Gamze Sevri Ekren Asici,Ayşegül Bildik et al.
Irem Bayar et al.
Hypoxia can cause significant changes in the glucose metabolism of cancer cells that prefer aerobic glycolysis for energy production instead of the conventional oxidative phosphorylation mechanism. In this study, breast cancer cells (MCF-7)...
In Silico Molecular Docking of Phytochemicals for Type 2 Diabetes Mellitus Therapy: A Network Pharmacology Approach [0.03%]
基于网络药理学的植物化学成分治疗2型糖尿病 mellitus 的分子对接研究
Sooriyakala Rani Sri Prakash,Sree Meenakshi Kamalnath,Arul Jayanthi Antonisamy et al.
Sooriyakala Rani Sri Prakash et al.
Identification of potential lead molecules in herbal medicines is crucial not only for validation but also for drug discovery. This study was focused on identifying the therapeutic mechanisms of 10 common herbs used to treat type 2 diabetes...
Biological Activity of Mouse OX40L-Igg Purified With Two Novel Resins [0.03%]
两种新型树脂纯化的小鼠OX40L-IgG的生物活性
Hossein Rezvan,Selman A Ali,Sahar Hamoonnavard et al.
Hossein Rezvan et al.
One of the important stimulating molecules for the function of T lymphocytes is tumor necrosis factor receptor OX40 (CD134), activated by its cognate ligand OX40L (CD134L, CD252). OX40L interactions have been proposed as a potential therape...
LRRTM3 Genetic Variations, rs1925575, and rs1925608 Contributed to Autism Spectrum Disorder Trait Severity: An Observation in The Indian Probands [0.03%]
印度患者的遗传变异体与自闭症谱系障碍严重程度有关：对LRRTM3基因rs1925575和rs1925608多态性的观察研究
Nilanjana Dutta,Sharmistha Saha,Mahasweta Chatterjee et al.
Nilanjana Dutta et al.
Surface proteins containing leucine-rich repeat (LRR) are essential for the formation of synapses. Therefore, proteins containing aberrant LRR regions are speculated to cause synaptic dysfunction, an abnormality often associated with Autism...
Optimization of Fluorapatite/Bioactive Glass Nanocomposite Foams as Bone Tissue Scaffold: An in Vivo Study [0.03%]
优化氟磷灰石/生物活性玻璃纳米复合多孔材料作为骨组织工程支架的体内研究
Seyedali Seyedmajidi,Maryam Seyedmajidi,Sina Haghanifar
Seyedali Seyedmajidi
The present study investigated the suitability of nanocomposite foams of fluorapatite and bioactive glass (FA /BG) in different weight ratios as scaffolds for bone tissue in rat tibia regeneration to determine the optimal composition. FA an...
Has_circ_0008285/miR-211-5p/SIRT-1 Axis Suppress Ovarian Cancer Cells Progression [0.03%]
circ_0008285/miR-211-5p/SIRT-1轴通过调控FOXM1抑制卵巢癌细胞进展
Khadijeh Elmizadeh,Ali Homaei,Ensiyeh Bahadoran et al.
Khadijeh Elmizadeh et al.
The significant functional role of circular RNAs (circRNAs) in the progression of malignant tumors, including ovarian cancer, has been shown in various studies. In this study, we aimed to investigate the abnormal expression of hsa_circ_0008...
Evaluation of Drug Resistance in the Tamoxifen-treated MKN-45 Gastric Cancer Cell Line via the Epithelial-mesenchymal Transition Signaling Pathway [0.03%]
通过上皮间质转化信号通路评估他莫昔芬治疗胃癌MKN-45细胞系的耐药性
Zeinab Mahdian,Mahdi Pouramir,Hassan Akrami et al.
Zeinab Mahdian et al.
One of the major challenges in gastric cancer (GC) chemotherapy is the phenomenon of multi-drug resistance (MDR). The epithelial-mesenchymal transition (EMT) and its key molecules, transforming growth factor-β (TGFβ) and SMAD2, play a cen...
Genetic Contribution of the Adrenergic, Cholinergic, and Serotonergic Systems to Leiomyoma Development and Treatment [0.03%]
肾上腺素能、胆碱能和血清素能系统对子宫平滑肌瘤发生和发展的影响及其在治疗中的作用的遗传学研究
Ângel Inácio,Laura Aguiar,Raquel Carrilho et al.
Ângel Inácio et al.
The link between the autonomic nervous system and tumor biology is being unfold. We aim to study the contribution of genes of the adrenergic (ADBR2 - rs1042713, NM_000024.6:c.46G>A, NP_000015.2:p. Gly16Arg), cholinergic (CHRNA5 - rs16969968...
Effect of Capparis spinosa Fruit Hydroalcoholic Extract on Paraquat-Induced Pulmonary Fibrosis in the Rat [0.03%]
Capparis spinosa果实水醇提物对(paraquat诱导的大鼠)肺纤维化的影响
Tahmine Ostovar,Sahar Rezaei,Hajar Shokri-Afra et al.
Tahmine Ostovar et al.
Pulmonary fibrosis (PF) is a lethal inflammatory disease and there has been no effective medication for this progressive disease up to now. Paraquat is commonly used in agricultural settings to control weed growth and is one of the importan...
EBV and HPV Infections in Colorectal Cancer and Their Effect on P53 and P16 Protein Expression [0.03%]
EB病毒和人乳头瘤病毒感染与结直肠癌中P53和P16蛋白表达的关系
Arefeh Ebrahimian Shiadeh,Vahideh Hamidi Sofiani,Saghar Saber Amoli et al.
Arefeh Ebrahimian Shiadeh et al.
Viral infections contribute to 15-20% of newly diagnosed cancers worldwide. There is evidence of a possible etiological role of Epstein-Barr virus (EBV) and high-risk human papillomaviruses (HR-HPVs) in colorectal carcinoma (CRC). Loss of p...