Emergence of OptrA Gene Mediated Linezolid Resistance among Enterococcus Faecium: A Pilot Study from a Tertiary Care Hospital, India [0.03%]
印度一家三级护理医院的Enterococcus faecium中由OptrA基因介导的利奈唑胺耐药性的出现：一项初步研究
Vandana Rani,Ajit Prakash,Mohammad Amin-Ul Mannan et al.
Vandana Rani et al.
E. faecium is the third most common cause of nosocomial infections. Linezolid (LNZ) is a reserve antibiotic recommended for infections caused by vancomycin resistant E. faecium (VREfm). The aim of the present study was to investigate the pr...
Cardiac Glycoside Oleandrin Suppresses EMT Ability in Endometrial Carcinoma Cells [0.03%]
夹竹桃糖苷 oleandrin 抑制子宫内膜癌细胞上皮间质转化能力
Fatma Secer Celik,Canan Eroglu Gunes,Ercan Kurar
Fatma Secer Celik
Endometrial carcinoma is one of the most common types of cancer among women. The progression of cancer occurs via the Epithelial- Mesenchymal Transition (EMT) pathway. Cells lose their epithelial properties and become mobile. For this reaso...
CD44 rs13347C>T Variants in 3'UTR and Prostate Neoplasms: A Case-control Study and Bioinformatics Approach [0.03%]
一项关于CD44基因多态性与前列腺肿瘤关系的病例对照研究及生物信息学方法分析
Emadoddin Moudi,Mohammadkazem Heydari,Abasalt Hosseinzadeh Colagar
Emadoddin Moudi
CD44, a cell-surface receptor and a key player in cellular signaling, can act as both tumor suppressor and promoter. This study aimed to investigate the association of CD44 rs13347C>T variants with prostate neoplasms, including both benign ...
Soudeh Ghafouri-Fard,Leila Gholami,Elham Badrlou et al.
Soudeh Ghafouri-Fard et al.
Periodontitis is a chronic inflammatory condition affecting a large population all over the world. This condition is linked with abnormal expression of numerous genes. We measured levels of CYFIP1, KDR, RABGGTA, RABGGTB and FOXD2 in gingiva...
Unraveling Roles of miR-27b-3p as a Potential Biomarker for Breast Cancer in Malay Women via Bioinformatics Analysis [0.03%]
基于生物信息学分析的miR-27b-3p作为乳腺癌潜在生物标志物的作用机制研究
Ab Rashid Jusoh,Tengku Ahmad Damitri Al-Astani Bin Tengku Din,Muhammad-Redha Abdullah-Zawawi et al.
Ab Rashid Jusoh et al.
Abnormal miRNA expression has been associated with breast cancer. Knowing miRNA and its target genes gives a better understanding of the biological mechanism behind the development of breast cancer. Here, we evaluated the potential prognost...
Isolation of Cells and Exosomes from Glioblastoma Tissue to Investigate the Effects of Ascorbic Acid on the c-Myc, HIF-1α, and Lnc-SNHG16 Genes [0.03%]
从胶质母细胞瘤组织中分离细胞和外泌体以研究抗坏血酸对c-Myc，HIF-1α和Lnc-SNHG16基因的影响
Masoumeh Eliyasi Dashtaki,Alireza Tabibkhooei,Sepideh Parvizpour et al.
Masoumeh Eliyasi Dashtaki et al.
Glioblastoma multiforme (GBM) is incurable with routine treatments. Ascorbic acid (Asc) has antioxidant and anti-cancer properties. However, its specific anti-cancer mechanisms are only partially understood. In this study, the effect of Asc...
Combination Therapy in Cancer: Doxorubicin in Combination with an N-terminal Peptide of Endostatin Suppresses Angiogenesis and Stimulates Apoptosis in the Breast Cancer [0.03%]
癌症的联合治疗：阿霉素与端粒肽的结合可以抑制乳腺癌中的血管增生并促进细胞凋亡
Narges Sarabi,Reyhane Chamani,Elham Assareh et al.
Narges Sarabi et al.
The combination of chemotherapy drugs with angiogenesis inhibitors improves response and survival and reduces the cytotoxic side effects and drug resistance in patients compared to chemotherapy alone. Here, we investigated the efficacy of t...
Isoproterenol Alters Metabolism, Promotes Survival and Migration in 5-Fluorouracil-Treated SW480 Cells with and without Beta-hydroxybutyrate [0.03%]
异丙肾上腺素改变代谢，促进5-氟尿嘧啶处理的SW480细胞（有或没有β-羟基丁酸）的生存和迁移
Azam Shakery,Katayoun Pourvali,Ghazaleh Shimi et al.
Azam Shakery et al.
People with cancer often experience long-term physical and psychological stress, which can have a significant impact on tumor metabolism and treatment. The effects of adrenergic signaling on metabolic pathways are well known, but only a few...
Mesenchymal Stem Cells Therapy Led to the Improvement of Spatial Memory in Rats with Alzheimer's disease Through Changing the Expression of LncRNA TUSC7/ miR-449a/ PPARγ and CD36 Genes in the Brain Tissue [0.03%]
间充质干细胞治疗通过改变阿尔茨海默病大鼠脑组织中长链非编码RNA TUSC7/miR-449a/PPARγ和CD36基因的表达改善空间记忆
Seyedeh Pardis Pezeshki,Mehrnaz Karimi Darabi,Zahra Nazeri et al.
Seyedeh Pardis Pezeshki et al.
Mesenchymal stem cells (MSCs) have the ability to phagocytize amyloid beta (Aβ) plaques and lower inflammation through the activity of microglia. Peroxisome proliferator-activated receptor gamma (PPARγ) is a protein involved in reducing i...
Stigmasterol- an Acetylcholinesterase Inhibitor from Phormidium retzii with relevance to Alzheimer's disease Therapy [0.03%]
菜油甾醇—来自胶被束丝藻的乙酰胆碱酯酶抑制剂及其对阿尔茨海默病治疗的意义
Rincy Yesudas,Vinoth Kumar Thirumalairaj,Geetharamani Durairaj et al.
Rincy Yesudas et al.
This study observed in vitro screening, purification and identification of cholinesterase inhibitors from the microalgae Phormidium retzii. Mixed microalgal culture was screened from freshwater samples for Phormidium sp. Single colony was p...