An Intricate Relationship Between miR-155-5p Expression and Oxidative Stress in Bladder Cancer Patients Treated with Calmette-Guerin Immunotherapy [0.03%]
BCG免疫治疗膀胱癌患者中miR-155-5p表达与氧化应激之间的复杂关系
Mohammad Mehdi Darzi,Nahid Neamati,Farzin Sadeghi et al.
Mohammad Mehdi Darzi et al.
Treatment failure after intravesical instillation of Bacillus Calmette-Guerin immunotherapy (BCG) for non-muscle-invasive bladder cancer (BCa) occurs frequently. The exact effects of BCG on cellular redox status and gene expression remain u...
Evaluation of the Immune Checkpoints, TIM-3 and PD-1, as well as Anti-Inflammatory Cytokines IL-10, and TGF-β along with Diseases Activity in Chronic Spontaneous Urticaria [0.03%]
TIM-3和PD-1免疫检查点及其抗炎细胞因子IL-10和TGF-β在慢性自发性荨麻疹活动度中的作用评估
Hadi Sadeghi,Javad Ghaffari,Javad Rajabi et al.
Hadi Sadeghi et al.
Chronic spontaneous urticaria (CSU) is a skin disease caused by mast cells that produce inflammatory mediators. Immune checkpoint receptors such as program death-1 (PD-1) and T-cell immunoglobulin and mucin domain 3 (TIM-3) are essential fo...
Evaluation of the Cytotoxicity of Secondary Bioactive Compounds Produced by Streptomyces in Soil against a Colon Cancer Cell Line [0.03%]
土壤中链霉菌产生的次级生物活性化合物对结肠癌细胞系 cytotoxicity 的评估
Mehri Hosseini,Abbas Akhavan Sepahi,Kumarss Amini et al.
Mehri Hosseini et al.
Colorectal cancer is one of the most serious malignancies affecting humans. In this study, Streptomyces bioactive chemicals extracted from soil were analyzed for their anti-colorectal-cancer and antibacterial properties. A total of 100 soil...
Cytoprotective Effect of Gallic Acid against Injuries Promoted by Therapeutic Ionizing Radiation in Preosteoblast Cells [0.03%]
没食子酸对预成骨细胞中辅助性电离辐射损伤的细胞保护作用
Renata Sousa Leite,Rogério Gonçalves da Rocha,Angeliny Tamiarana Lima Tabosa et al.
Renata Sousa Leite et al.
Gallic acid (GA) is a powerful antioxidant extracted from plants of the Brazilian Cerrado. Oxidative stress plays an important role in the occurrence of radiation-induced osteonecrosis in patients treated for head and neck cancer. There is ...
Dysregulation of LncRNAs ANRIL, MALAT1, and LINC00305 in Coronary Slow Flow Patients: Implications for Inflammation and Endothelial Dysfunction [0.03%]
冠脉慢血流患者中长链非编码RNAANRIL、MALAT1和LINC00305的失调：对炎症和内皮功能障碍的意义
Mohammad Esmail Gheidari,Asal Geramifard,Mahyar Rafiei
Mohammad Esmail Gheidari
Coronary Slow Flow (CSF) is observed in individuals who experience delayed blood supply in the coronary arteries. Inflammation and endothelial dysfunction may play a role in the etiology and development of CSF. The current investigation aim...
Evaluations of Biomarkers CDX1 and CDX2 in Gastric Cancer Prognosis: A Meta-analysis [0.03%]
胃癌预后标志物CDX1和CDX2的评估:一项荟萃分析
Azadeh Khayyat,Mohammad Ali Esmaeil Pour,Olia Poursina et al.
Azadeh Khayyat et al.
CDX1 and CDX2 are homeobox-type transcription factors that are potential biomarkers and are associated with prognostic significance in intestinal-type gastric cancer early disease before lymph node metastasis is associated with better progn...
In Silico and In vitro Evaluations of the Antibacterial Activities of HIV-1 Nef Peptides against Pseudomonas aeruginosa [0.03%]
HIV-1Nef肽对铜绿假单胞菌抗菌活性的计算及体外评价
Eman Koosehlar,Hassan Mohabatkar,Mandana Behbahani
Eman Koosehlar
One of the burning issues facing healthcare organizations is multidrug-resistant (MDR) bacteria. P. aeruginosa is an MDR opportunistic bacterium responsible for nosocomial and fatal infections in immunosuppressed individuals. According to p...
Predicting Survival in Glioblastoma Using Gene Expression Databases: A Neural Network Analysis [0.03%]
基于基因表达数据库的胶质母细胞瘤患者生存预测：神经网络分析
Parisa Azimi,Taravat Yazdanian,Amirhosein Zohrevand et al.
Parisa Azimi et al.
Glioblastoma (GBM) is the most aggressive and lethal brain tumor. Artificial neural networks (ANNs) have the potential to make accurate predictions and improve decision making. The aim of this study was to create an ANN model to predict 15-...
Gene Expression of Glycolysis Enzymes in MCF-7 Breast Cancer Cells Exposed to Warburg Effect and Hypoxia [0.03%]
沃邦效应和低氧条件下MCF-7乳腺癌细胞糖酵解酶的基因表达
Irem Bayar,Gamze Sevri Ekren Asici,Ayşegül Bildik et al.
Irem Bayar et al.
Hypoxia can cause significant changes in the glucose metabolism of cancer cells that prefer aerobic glycolysis for energy production instead of the conventional oxidative phosphorylation mechanism. In this study, breast cancer cells (MCF-7)...
In Silico Molecular Docking of Phytochemicals for Type 2 Diabetes Mellitus Therapy: A Network Pharmacology Approach [0.03%]
基于网络药理学的植物化学成分治疗2型糖尿病 mellitus 的分子对接研究
Sooriyakala Rani Sri Prakash,Sree Meenakshi Kamalnath,Arul Jayanthi Antonisamy et al.
Sooriyakala Rani Sri Prakash et al.
Identification of potential lead molecules in herbal medicines is crucial not only for validation but also for drug discovery. This study was focused on identifying the therapeutic mechanisms of 10 common herbs used to treat type 2 diabetes...