Increased Expression of ITGB 3 in CLL Patient leukemia Cells by Exposure to Cold Physical Plasma and Plasma-treated Medium [0.03%]
冷等离子体和经等离子体处理的培养基对CLL患者白血病细胞ITGB3表达的影响
Monireh Golpour,Farshad Sohbatzadeh,Mina Alimohammadi et al.
Monireh Golpour et al.
Chronic lymphocytic leukemia (CLL) is the most prevalent hematological cancer, with various medical interventions. In the recent decade, cold physical plasma has become an interesting agent for future cancer therapy. The goal of this study ...
Biosynthesis of Copper Oxide-Silver Nanoparticles from Ephedra Intermedia Extract and Study of Anticancer Effects in HepG2 Cell Line: Apoptosis-Related Genes Analysis and Nitric Oxide Level Investigations [0.03%]
Ephedra Intermedia提取物合成铜氧化银纳米粒子及其在HepG2细胞系抗癌效应的研究：与凋亡相关基因分析及一氧化氮水平研究
Nazanin Naderi,Azadeh Mohammadgholi,Nastaran Asghari Moghaddam
Nazanin Naderi
Liver cancer treatment faces significant obstacles such as resistance, recurrence, metastasis, and toxicity to healthy cells. Biometallic nanoparticles (NPs) have emerged as a promising approach to address these challenges. In this study, c...
Extracellular Signal-Regulated Kinase Inhibitor SCH772984 Augments the Anti-Cancer Effects of Gemcitabine in Nanoparticle Form in Pancreatic Cancer Models [0.03%]
一种细胞外信号调节激酶抑制剂SCH772984能够增强纳米颗粒型吉西他滨在胰腺癌模型中的抗癌效果
Gauthami G Nair,Elena D Linster,Priyanka Ray et al.
Gauthami G Nair et al.
Pancreatic ductal adenocarcinoma (PDAC) is a lethal disease with a poor response to the limited treatment options currently available. Hence, there is a need to identify new agents that could enhance the efficacy of existing treatments. Thi...
LINC01366 and LINC01433 in Glioblastoma Multiforme: A Potential Role at the Intersection of Inflammation and Angiogenesis [0.03%]
长链非编码RNA LINC01366和LINC01433在胶质母细胞瘤中的作用：炎症与血管生成交点处的潜在角色分析
Sorush Jafari,Masih Saboori,Sorayya Ghasemi
Sorush Jafari
Glioblastoma multiforme (GBM) is an aggressive cancer with a poor prognosis. Inflammation and angiogenesis are important processes in GBM that are interrelated. In this study, bioinformatic investigations were performed to detect common and...
Plasma TNF-α Elevation in Biologic Naive Rheumatoid Arthritis Patients Belonging to a Population with New Mutations in TLR4 and CYP51A1 genes without Association with Disease-Related Antibodies Levels [0.03%]
TLR4和CYP51A1基因新突变人群中的类风湿关节炎患者血浆TNF-α升高与疾病相关自身抗体水平无关联
Ezatollah Mosavi,Mojgan Bandehpour,Amrollah Mostafazadeh et al.
Ezatollah Mosavi et al.
In a system biology-based study, we previously reported that IL-6 and IL6R -specific m-RNA levels were elevated in leukocytes of patients with Rheumatoid arthritis (RA). Here, the association of toll-like receptor4 (TLR4) rs 141534085 and c...
Suppressive Potential of Rosmarinus officinalis L. Extract against Triple-Negative and Luminal A Breast Cancer [0.03%]
罗勒提取物对三阴性及 luminal A 型乳腺癌的抑制作用
Kamran Eghbalpour,Nahid Eghbalpour,Saideh Khademi et al.
Kamran Eghbalpour et al.
Rosemary is an aromatic plant with ancient and modern applications as a spice and herbal remedy. Due to the strong antioxidant potential of rosemary, the present study investigated the anti-proliferative and pro-apoptotic characteristics of...
Losartan as a Reproposing Therapeutic Agent in Acute Respiratory Distress Syndrome: Modulating Inflammatory Responses and Cytokine Production [0.03%]
洛索洛芬作为急性呼吸窘迫综合征的再提议治疗药物：调节炎症反应和细胞因子生成
Khate Sripratak,Phumin Chamsodsai,Jeeraprapa Siriwaseree et al.
Khate Sripratak et al.
Seeking a new drug has become a significant milestone in drug discovery. However, it might not be immediately used in urgent situations or during a pandemic. Acute Respiratory Distress Syndrome (ARDS) contributes to mild-to-severe symptoms ...
Astaxanthin Co-treatment with Low Dose Methotrexate Increases the Cell Cycle Arrest and Ameliorates the Methotrexate-induced Inflammatory Response in NALM-6 [0.03%]
虾青素联合小剂量甲氨蝶呤通过增加细胞周期停滞和改善甲氨喋呤诱导的炎症反应抑制NALM-6细胞增殖作用研究
Nastaran Moridi,Mahsa Najafzadeh,Mahtab Sayedi et al.
Nastaran Moridi et al.
Methotrexate (MTX), an antimetabolite agent, is widely used for acute lymphoblastic leukemia treatment, despite its association with significant organ dysfunction. Astaxanthin (AST) is a natural carotenoid which has recently been emerged as...
Ehsan Kakavandi,Jila Yavarian,Mahdieh Farzanehpour et al.
Ehsan Kakavandi et al.
Ebola virus (EBOV) is a life-threatening and virulent pathogen that kills approximately 90 percent of infected individuals. Nowadays, microRNAs (miRNAs) have become a promising option for more efficient screening, diagnosis, monitoring, and...
Diversity of Memory CD8+ T Cells in Tumor-Draining Lymph Nodes from Patients with Bladder Cancer [0.03%]
膀胱癌患者肿瘤引流淋巴结中记忆CD8+t细胞的多样性
Ali Ariafar,Zahra Mansourabadi,Shahin Rasekh et al.
Ali Ariafar et al.
The role of memory T cells in orchestrating memory responses to previously known tumor antigens is well documented. The aim of this study was to assess the frequency of different memory T cell subsets in tumor-draining lymph nodes of patien...