Possible Trace of HTLV-1 Virus in Modulation of Cbl-b, ITCH, and PP2A Suppressor Genes [0.03%]
HTLV-1病毒可能通过调节Cbl-b、ITCH和PP2A抑制基因产生影响
Atefeh Bahavar,Abdolvahab Moradi,Hamed Mohammadi et al.
Atefeh Bahavar et al.
For almost 40 years, human T-lymphotropic virus type 1 (HTLV-1) has posed a persistent challenge in managing the major diseases associated with HTLV-1. Intracellular inhibitors are critical regulators of T cell activation, and their functio...
Improvement of the Antimicrobial and Antibiofilm Activity of AH Plus Sealer with Chitosan Nanoparticles and Arginine against Enterococcus faecalis and Candida albicans [0.03%]
纳米甲壳素和精氨酸增强AH plus封闭剂对粪肠球菌和白色念珠菌的抗菌和抗生物膜活性的改善
Elham Khoshbin,Hamed Karkehabadi,Mohammad Yousef Alikhani et al.
Elham Khoshbin et al.
The success of endodontic treatments can be significantly impaired by persistent microbial pathogens, especially Enterococcus faecalis (E. faecalis) and Candida albicans (C. albicans). The aim of this study was to investigate how the incorp...
Effects of Curcumin on Biofilm Production and Associated Gene in Multidrug-Resistant Acinetobacter baumannii Isolated from Hospitalized Patients [0.03%]
姜黄素对医院感染患者多重耐药鲍曼不动杆细菌生物膜及其相关基因的影响
Kasra Javadi,Mohammad Hossein Ahmadi,Mehdi Rajabnia et al.
Kasra Javadi et al.
Multi-drug-resistant (MDR) Acinetobacter baumannii has become a major global healthcare concern due to its opportunistic infections and high antibiotic resistance. This investigation is intended to investigate curcumin's potential anti-bact...
Innovative Approaches for Molecular Targeted Therapy of Breast Cancer: Interfering with Various Pathway Signaling [0.03%]
乳腺癌分子靶向治疗的新方法：干扰各种途径的信号传输
Mahyar Haki,Reihaneh Bayat
Mahyar Haki
Breast cancer encompasses a diverse array of conditions classified as hormone receptor-positive, human epidermal growth factor receptor 2-positive, and triple-negative breast cancer subtypes, dictating treatment approaches. The therapeutic ...
SLC7A11 Inhibitors Represent a Promising Therapeutic Target by Facilitating the Induction of Ferroptosis in Breast Cancer [0.03%]
通过促进乳腺癌中铁死亡的诱导，SLC7A11抑制剂成为一种有前景的治疗靶点
Rojin Azizi,Hanan Hassan Ahmed,Radhwan Abdul Kareem et al.
Rojin Azizi et al.
It is predicted with near certainty that an estimated 310,720 women will be diagnosed with invasive breast carcinoma in 2024, while the number of men will be significantly lower at around 2,800, highlighting the alarming prevalence of this ...
Gambogic Acid Mitigates Nephropathy by Inhibiting Oxidative Stress and Inflammation in Diabetic Rats [0.03%]
黄酸通过抑制氧化应激和炎症减轻糖尿病大鼠的肾病
Ruttiya Thongrung,Sarawut Lapmanee,Penjai Thongnuanjan Bray et al.
Ruttiya Thongrung et al.
Diabetic nephropathy is a leading cause of end-stage renal disease globally, with limited treatment options to prevent its progression. Gambogic acid (GA), a xanthone isolated from Garcinia hanburyi, has shown notable anti-oxidative, anti-i...
Elucidating the Role of LINC01980 in Laryngeal Cancer: From Expression Profiling to Regulatory Network Prediction [0.03%]
阐明LINC01980在喉癌中的作用：从表达谱分析到调控网络预测
Masoumeh Razipour,Zeinab Jamali,Elham Ghadami et al.
Masoumeh Razipour et al.
Laryngeal squamous cell carcinoma (LSCC) remains a significant global health challenge despite advances in treatment. This study investigated the involvement of LINC01980, a long non-coding RNA, in LSCC pathogenesis. We conducted an integra...
Non-coding RNA in the Regulation of Gastric Cancer Tumorigenesis: Focus on microRNAs and Exosomal microRNAs [0.03%]
非编码RNA在胃癌发生发展中的作用研究微小RNA和外泌体微小RNA的研究重点
Niyousha Vakilzadehian,Yasamin Moradi,Omer Qutaiba B Allela et al.
Niyousha Vakilzadehian et al.
Gastric cancer has become the leading type of cancer on an international scale, with metastatic cancer being the leading cause of mortality associated with this illness. Consequently, methods for early detection have been established, mainl...
Anti-tumor Effects of Recombinant Clostridium α-Toxin on Breast Cancer: An In Vitro and In Vivo Study [0.03%]
重组芽胞杆菌α毒素抗肿瘤作用的体内外研究
Nahid Rezaei Khozani,Mohammad Shayesteh Pour,Mina Yekani et al.
Nahid Rezaei Khozani et al.
Cancer is the second leading cause of death worldwide, surpassed only by cardiovascular diseases. This study investigated the anticancer effects of recombinant Clostridium α-toxin on breast cancer, both in vitro and in vivo. The entire cod...
Potential Otubain1 Inhibitor, an Approach for a Treatment against Breast Cancer [0.03%]
潜在的Otubain1抑制剂，一种治疗乳腺癌的新方法
Andrea Muñoz-Ayala,Victor G García-González,Angel Pulido-Capiz et al.
Andrea Muñoz-Ayala et al.
The develop of new anticancer drug continues worldwide and one of the new therapeutic targets to reach it is Otubain 1 (OTUB1), since OTUB1 has functions related to prognosis in a variety of tumors and is strongly related to tumor prolifera...