SIRT1 and miR-34a as Potential Plasma Biomarkers in the Acute Phase of Ischemic Stroke [0.03%]
缺血性卒中急性期SIRT1和miR-34a的潜在血浆生物标志物价值研究
Mitra Ansari Dezfouli,Moslem Esmati,Seyed Khalil Rashidi et al.
Mitra Ansari Dezfouli et al.
Stroke is the major cause of disability and mortality worldwide. Identification of molecular biomarkers in the early hours after stroke is important in terms of both diagnostic and therapeutic applications. miR-34a, a highly expressed miRNA...
Combined Methylation Analysis of SDC2 and TFPI2 in Plasma: A Noninvasive Liquid Biopsy Approach for Early Detection of Colorectal Polyp [0.03%]
血浆SDC2和TFPI2甲基化联合分析在结直肠息肉早期无创检测中的应用研究
Milad Khabbazpour,Mohammad Heiat,Ashraf Karbasi et al.
Milad Khabbazpour et al.
Early detection is crucial for improving survival rates in colorectal cancer (CRC). This study evaluates the non-invasive diagnosis of polyps by assessing the methylation status of the TFPI2 and SDC2 genes in plasma. This study enrolled 27 ...
TNF-α and E-Selectin as Valuable Biomarkers in Patients with Acute Coronary Artery Syndrome [0.03%]
肿瘤坏死因子-α和E-选择素在急性冠脉综合征患者中的生物标志价值评估研究
Hassan Jabbar Auda,Ali Mohammed Barakat,Hassan Sarhan Sachet et al.
Hassan Jabbar Auda et al.
Coronary artery disease (CAD) remains the leading cause of mortality worldwide, especially in developing countries, with dyslipidemia being a major risk factor. This study aimed to evaluate lipid parameters and inflammatory biomarkers-E-sel...
Dose-Dependent Modulation of NMDA Receptors: Neuroprotective Mechanisms against Oxidative Stress in Hippocampal Neurons [0.03%]
NMDA受体的剂量依赖性调节：抗氧化应激保护海马神经元的作用机制
Marjan Nikbakhtzadeh,Asal Behboudian,Maryam Mohammadnia et al.
Marjan Nikbakhtzadeh et al.
N-Methyl-D-Aspartate (NMDA) receptors are involved in synaptic plasticity and neuronal communication. They have various responses to oxidative stress based on the dosage of agonists or antagonists that may be applied. This study focuses on ...
Candida albicans Impact on the Progression, Morphology, and Cellular Integrity of Biofilm Formation on the Surfaces of Implants; Current Knowledge and Future Perspectives [0.03%]
白色念珠菌对植入物表面生物膜形成进展、形态和细胞完整性的影响；现有知识与未来展望
Seçkin Yalçın,Selin Özel,Dilara Çamyar et al.
Seçkin Yalçın et al.
The capacity of Candida albicans to adhere to diverse oral substrates constitutes a pivotal preliminary phase in the formation of a pathogenic fungal biofilm. Yeast cells demonstrate a considerable ability to bind to host tissues, encompass...
Osteogenic potential of human dental pulp stem cells, and human dermal fibroblasts exposed hydroxyapatite nanoparticles: A comparative in vitro study [0.03%]
羟基磷灰石纳米粒子诱导牙髓干细胞和人皮肤成纤维细胞成骨潜能的比较体外研究
Mohsen Naseri,Sepideh Sarfi,Mohammad Yahya Hanafi-Bojd et al.
Mohsen Naseri et al.
This study aimed to evaluate the osteogenic response of human dermal fibroblasts (hDFs) and human dental pulp stem cells (hDPSCs) when exposed to hydroxyapatite nanoparticles (HA-NPs), which are commonly employed biomaterials in the field o...
Oral squamous cell carcinoma pharmacological treatment; A long non-coding RNAs (long ncRNAs) story [0.03%]
长非编码RNA（lncRNA）在口腔鳞状细胞癌药物治疗中的作用机制研究故事化叙事文献计量学综述与展望
Azita Sadeghzade,Ali Jafarian,Amir Hossein Davodpour et al.
Azita Sadeghzade et al.
Oral squamous cell cancer (OSCC) is a major global health issue, ranking sixth in prevalence, particularly in Asia. The diagnosis often occurs late due to inadequate early screening, resulting in a dismal five-year survival rate of around 5...
Anti-tumor Effects of Curcumin and ABT-737 in Combination Therapy for Glioblastoma in Vivo [0.03%]
姜黄素和ABT-737联合治疗对胶质母细胞瘤的抗肿瘤效应的体内研究
Zahra Sadat Miri,Hossein Bagheri,Alireza Amani et al.
Zahra Sadat Miri et al.
The resistance of tumor cells to ABT-737 can be attributed to alterations in the equilibrium of Bcl-2 family proteins. In this study, the effect of curcumin on the Mcl-1expression and the sensitivity of glioblastoma cells to ABT-737 were ex...
Colorectal Cancer: Risk Factors, Novel Approaches in Molecular Screening and Treatment [0.03%]
结直肠癌：危险因素，分子筛查和治疗的新方法
Khatereh Anbari,Koroush Ghanadi
Khatereh Anbari
By 2040 the burden of colorectal cancer will increase to 3.2 million new cases per year and 1.6 million deaths per year. This highlights the importance of improving preventive measures and treatment strategies. This piece concisely overview...
Down Expression of Zyxin is Associated with Down Expression of p53 in Colorectal Cancer [0.03%]
结肠直肠癌中Zyxin的低表达与p53的低表达有关
Hossein Mohammadi,Ebrahim Shakiba,Rezvan Rostampour et al.
Hossein Mohammadi et al.
Colorectal cancer (CRC), which is among the most prevalent cancers worldwide, is caused by environmental and genetic factors. It has been shown that the p53 gene is associated with CRC pathogenesis; moreover, Zyxin (ZYX) may play a role in ...