Evaluation of Lactobacillus delbrueckii Supernatant Effects on Cell Cycle Regulation, Apoptosis Induction, and Gene Expression in HT-29 Colorectal Cancer Cells [0.03%]
乳酸菌上清液对HT-29结肠癌细胞周期调控、促凋亡及基因表达的影响评价
Mohammad Reza Majid Khoshkholgh Pahlaviani,Amir Emami,Seyed Mohammad Mehdi Mahmoodi et al.
Mohammad Reza Majid Khoshkholgh Pahlaviani et al.
This study investigated the anti-tumor properties of Lactobacillus delbrueckii, a probiotic bacterium, against HT-29 human colorectal cancer cells. The primary objective was to evaluate the effects of Lactobacillus delbrueckii supernatant o...
Counting Copies, Making Medicines: A Roadmap for the MSC-EV-microRNAome [0.03%]
计数、造药：MSC-EV-微小RNA图谱路线指导手册
Farshid Yeganeh,Hadi Parsian
Farshid Yeganeh
Enhancing Osteogenesis in Dental Implants: ZNF710-AS1 and miR-146a-5p in Smad Signaling Pathway Activation [0.03%]
牙种植体成骨分化的促进：Smad信号通路激活中的ZNF710-AS1和miR-146a-5p的作用
Reza Mahmoudi Anzabi,Naghmeh Shenasa,Ali Jafarian et al.
Reza Mahmoudi Anzabi et al.
Investigations have shown that understanding the regulatory mechanisms of the osteogenic differentiation of periodontal ligament stem cells (PDLSCs) can significantly enhance the regenerative capacity of periodontal tissues and mitigate per...
Innovative Aptamer-HRP Conjugation for Cardiac Troponin I Detection: A Novel ELASA Approach for AMI Diagnostics [0.03%]
心脏肌钙蛋白I检测的创新性适配子-HRP偶联物法：AMI诊断的新ELISA方法研究
Mahshid Bahari,Farshid Yeganeh,Ali Kargar
Mahshid Bahari
Acute myocardial infarction (AMI), a major global cause of mortality, is diagnosed using cardiac troponin I (cTnI). Antibody-based assays face challenges, prompting the exploration of aptamers. This study develops an aptamer-HRP probe and E...
Caffeine Modulates Cell Death and Telomerase Activity in Triple-negative Breast Cancer Cells [0.03%]
咖啡因调节三阴性乳腺癌细胞的细胞凋亡和端粒酶活性
Qanita Hana Amira,Shadira Anindieta Irdianto,Fadilah Fadilah et al.
Qanita Hana Amira et al.
Triple-negative breast cancer (TNBC) is an aggressive subtype defined by the lack of estrogen receptors (ER), progesterone receptors (PR), and HER2 expression, resulting in limited therapeutic options. Given this challenge, this study explo...
Navigating the Molecular Signaling: Deciphering Cancer Stem Cell Self-Renewal Pathways [0.03%]
破解癌症干细胞自我更新通路——揭秘分子信号传导
Seyed Nasser Hoseinian,Mohammad Saeedi,Mohammad Erfan Saravani et al.
Seyed Nasser Hoseinian et al.
Cancer stem cells (CSCs) are a subset of cells within tumors that exhibit stem cell-like characteristics, including the ability to self-renew and differentiate. CSCs are the cause of carcinogenesis and tumorigenesis. The expression of cell ...
Evaluation of the Antibacterial and Anti-Biofilm Activity of Chitosan-Arginine Nanoparticles and Sodium Fluoride against Streptococcus mutans [0.03%]
壳聚糖-精氨酸纳米颗粒和氟化钠对变异链球菌的抗菌及抑菌活性评估
Fahimeh Daneshyar,Mohammad Yousef Alikhani,Soudeh Tayebi et al.
Fahimeh Daneshyar et al.
Dental caries is among the most prevalent chronic diseases. It arises from bacterial biofilm formation on tooth surfaces due to metabolic activity. Streptococcus mutans (S. mutans) is a key pathogen implicated in the development of dental c...
Optimizing Production Conditions of a Caspian Sea Actinomycete Exhibiting Promising Antibacterial Activity Against Clinically-important Pathogens Using the Two-Factor Interaction/ Minimum Run Resolution IV Method [0.03%]
应用二因子交互作用/最小游程分辨率IV法优化里海链霉菌的生产条件以获得对临床重要病原菌具有抗菌活性的产物
Zeinab Jan,Hamed Norouzi Taheri,Abolghasem Danesh
Zeinab Jan
Natural products recovered from marine sediment have the potential for the treatment of various diseases. Streptomyces sp., strain MN38 which was previously isolated from the Caspian Sea of Iran was at first characterized based on its 16srR...
SARS-CoV-2 ORF7 subgenomic RNA and Host IFN-β Expression in COVID-19 Hospitalized Patients with Different Prognosis [0.03%]
不同预后的新型冠状肺炎住院患者SARS-CoV-2 ORF7亚基因组RNA和宿主IFN-β表达水平研究
Akbar Zirakjou,Farzin Sadeghi,Arefeh Ebrahimian Shiadeh et al.
Akbar Zirakjou et al.
The worldwide spread of COVID-19, triggered by SARS-CoV-2, has highlighted how viral accessory proteins contribute significantly to bypassing host immune defenses and increasing illness severity. This study investigates the relationship bet...
Colorectal Cancer; Novel Approaches in Chimeric Antigen Receptors (CAR) -T cell [0.03%]
结直肠癌;嵌合抗原受体(CAR)-T细胞新方法
Mahyar Haki,Mohammad Darvishi
Mahyar Haki
Colorectal cancer (CRC) is a popular type of cancer, characterized by high mortality and a notable impression on the well-being of individuals. The success of adoptive chimeric antigen receptor T (CAR-T) cell therapy in treating hematologic...