Monophosphoryl Lipid A and Retinoic Acid Combinations Increased Germ Cell Differentiation Markers Expression in Human Umbilical Cord-derived Mesenchymal Stromal Cells in an In vitro Ovine Acellular Testis Scaffold [0.03%]
单磷酸脂A和视黄酸联合促进人脐带间充质干细胞在绵羊去细胞睾丸支架中的生殖细胞分化标记物表达
Ali Shojaeian,Ameneh Mehri-Ghahfarrokhi,Mehdi Banitalebi-Dehkordi
Ali Shojaeian
Infertility is known as one of the most common problems among couples. In this regard, generation of male germ cells from adult stem ones are among the current promising priorities of researchers. Mesenchymal stromal cells (MSCs) were previ...
Downregulated Expression of WWOX in Cervical Carcinoma: A Case-Control Study [0.03%]
宫颈癌中WWOX表达下调：一项病例对照研究
Shikha Srivastava,Uday Pratap Shahi,Arti Divya et al.
Shikha Srivastava et al.
Integration of human papilloma virus (HPV) in human genome is a random event, and fragile sites are one of the most susceptible sites for viral integrations. WWOX (WW-domain containing oxidoreductase) gene harbours the second most common fr...
The Expression Pattern and Clinicopathological Importance of Hsa_circ_000425 in Colorectal Cancer [0.03%]
Hsa_circ_000425在结直肠癌中的表达及临床病理意义
Davood Mohammadi,Ali Bastani,Yazdan Zafari et al.
Davood Mohammadi et al.
Although colorectal cancer (CRC) is one of the most common cancers, the exact molecular mechanism of this cancer is not yet known. Circular RNAs (circRNAs), a class of non-coding RNAs, are newly identified and their role in the pathogenesis...
Association of Pathogenic Missense and Nonsense Mutations in Mitochondrial COII Gene with Familial Adenomatous Polyposis (FAP) [0.03%]
线粒体COII基因致病错义和无义突变与家族性腺瘤性息肉病(FAP)的关联性分析
Zahra Shaker Ardakani,Mohammad Mehdi Heidari,Mehri Khatami et al.
Zahra Shaker Ardakani et al.
Nuclear genetic mutations have been extensively investigated in solid tumors. However, the role of the mitochondrial genome remains uncertain. Since the metabolism of solid tumors is associated with aerobic glycolysis and high lactate produ...
Aberrant Expression of Immune-related MicroRNAs in Pediatric Patients with Asthma [0.03%]
儿童哮喘患者免疫相关microRNA的异常表达
Hala Gouda Elnady,Lobna Sayed Sherif,Naglaa Mohamed Kholoussi et al.
Hala Gouda Elnady et al.
MicroRNAs (miRNAs) have been implicated as regulatory molecules that could play a considerable role in the pathogenesis of different diseases including asthma. This work aims at exploring the role of miR-146a and miR- 106b in the pathogenes...
Differential Biological Behavior of Fibroblasts and Endothelial Cells under Aloe vera Gel Culturing [0.03%]
Aloesin缓释制剂的体外和体内研究
Saba Shafaie,Sina Andalib,Hajar Shafaei et al.
Saba Shafaie et al.
Aloe vera is used for its large variety of biological activities such as wound healing, anti-fungal, anti-inflammatory, hypoglycemic, immunomodulatory, gastroprotective, and anti-cancer. Although the beneficial effects of Aloe vera on wound...
Evaluation of Anti-inflammatory and Antioxidant Profile of Oleuropein in Experimentally Induced Ulcerative Colitis [0.03%]
橄榄苦素的抗炎和抗氧化作用评估：一种实验性溃疡性结肠炎模型研究
Muhammed Hassan Motawea,Hussein Ali Abd Elmaksoud,Mohamed Gamal Elharrif et al.
Muhammed Hassan Motawea et al.
Oleuropein is one of the main phenolic secoiridoid of the olive leaf extract, which is known for its antioxidant and anti-inflammatory effects. The main objective of the present study was to investigate the effectiveness of oleuropein in the ...
Folate System Gene Variant rs1801394 66A>G may have a Causal Role in Down Syndrome in the Eastern Indian Population [0.03%]
下甲基mal通路基因多态性rs1801394 66A> G可能在东部印度人唐氏综合症发生中起因果作用
Mahasweta Chatterjee,Tanusree Saha,Subhamita Maitra et al.
Mahasweta Chatterjee et al.
Down syndrome (DS) is associated with trisomy of the 21st chromosome in more than 95% cases. The extra chromosome mostly derives due to abnormal chromosomal segregation, i.e. non-disjunction, during meiosis. Earlier reports showed that abno...
EL4-derived Exosomes Carry Functional TNF-related Apoptosis-inducing Ligand that are Able to Induce Apoptosis and Necrosis in the Target Cells [0.03%]
EL4源外泌体携带的肿瘤坏死因子相关凋亡诱导配体具有在靶细胞中诱发凋亡和坏死的功能
Sajjad Tavakkoli,Fattah Sotoodehnejadnematalahi,Anwar Fathollahi et al.
Sajjad Tavakkoli et al.
Exosomes released by tumor cells play critical roles in tumor progression, immune cell suppression, and cancer metastasis. The aim of the present study was to investigate whether the exosomes released by EL4 cells carry a functional TNF-rel...
Plasma Levels of miR-27a, miR-130b, and miR-301a in Polycystic Ovary Syndrome [0.03%]
多囊卵巢综合征患者的血浆miR-27a、miR-130b和miR-301a水平检测
Zahra Pourteymour Fard Tabrizi,Sepideh Miraj,Shahram Tahmasebian et al.
Zahra Pourteymour Fard Tabrizi et al.
Polycystic ovary syndrome (PCOS) is a gynecological endocrine disorder in women of reproductive age. There is adequate evidence that suggests several microRNAs (miRNAs) are of great importance for PCOS. It seems that dysregulated expression...