The Biological Significance of Long noncoding RNAs Dysregulation and their Mechanism of Regulating Signaling Pathways in Cervical Cancer [0.03%]
长链非编码RNA失调在宫颈癌中的生物学意义及其调控信号通路的机制研究
Maryame Lamsisi,Lahcen Wakrim,Amal Bouziyane et al.
Maryame Lamsisi et al.
Despite the remarkable decrease in cervical cancer incidence due to the availability of the HPV vaccine and implementation of screening programs for early detection in developed countries, this cancer remains a major health problem globally...
Level of miR-101a and miR-107 in Human Adipose Mesenchymal Stem Cells Committed to Insulin-producing Cells [0.03%]
人脂肪间充质干细胞向胰岛素产生细胞分化过程中miR-101a及miR-107的表达水平研究
Hadi Rajabi,Somayeh Aslani,Reza Rahbarghazi
Hadi Rajabi
Mesenchymal stem cells have the fundamental ability to differentiate into multiple cells such as osteoblasts, neural cells, and insulin-producing cells. MicroRNAs (miRNAs) are single-strand and small non-coding RNAs involved in stem cells o...
Maha Mohamed Farid Aql,Seham Abd-El Ghafour Bahget,Naglaa Kholoussi et al.
Maha Mohamed Farid Aql et al.
Telomeres are nucleoprotein complexes present at the ends of chromosome to maintain its integrity. Telomere length is maintained by an enzyme called "telomerase". Thus, telomerase activity and telomere length are crucial for the initiation ...
Knockdown of c-MYC Controls the Proliferation of Oral Squamous Cell Carcinoma Cells in vitro via Dynamic Regulation of Key Apoptotic Marker Genes [0.03%]
c-MYC基因干扰通过动态调节关键凋亡标记基因控制体外口腔鳞状细胞癌增殖
Hussein Sabit,Huseyin Tombuloglu,Emre Cevik et al.
Hussein Sabit et al.
Oral squamous cell carcinoma (OSCC) is the most common malignant epithelial cancer occurring in the oral cavity, where it accounts for nearly 90% of all oral cavity neoplasms. The c-MYC transcription factor plays an important role in the co...
Differential Expression and Prognostic Significance of STARD3 Gene in Breast Carcinoma [0.03%]
乳腺癌中STARD3基因的差异表达及其预后意义
Abdul Fattah Salah Fararjeh,Ali Al Khader,Ezidin Kaddumi et al.
Abdul Fattah Salah Fararjeh et al.
StAR related lipid transfer domain containing 3 (STARD3) gene has been reported to be co-amplified with human epidermal growth factor receptor 2 (HER2) in breast carcinoma. STARD3 is necessary for cholesterol transfer and metabolism in tumo...
DCLK1 Inhibition Sensitizes Colorectal Cancer Cells to Radiation Treatment [0.03%]
抑制DCLK1可增强放射治疗对结直肠癌细胞的敏感性
Chiman Mohammadi,Ali Mahdavinezhad,Massoud Saidijam et al.
Chiman Mohammadi et al.
Colorectal cancer (CRC) is one of the most prevalent diagnosed cancers and a common cause of cancer-related mortality. Despite effective clinical responses, a large proportion of patients undergo resistance to radiation therapy. Therefore, ...
Quercetin Synergistically Enhances the Anticancer Efficacy of Docetaxel through Induction of Apoptosis and Modulation of PI3K/AKT, MAPK/ERK, and JAK/STAT3 Signaling Pathways in MDA-MB-231 Breast Cancer Cell Line [0.03%]
檞皮素通过诱导凋亡和调节PI3K / AKT，MAPK / ERK和JAK / STAT3信号通路增强MDA-MB-231乳腺癌细胞系中多西他赛的抗癌功效
Amir Safi,Esfandiar Heidarian,Reza Ahmadi
Amir Safi
Docetaxel is widely used in the treatment of metastatic breast cancer. However, its effectiveness is limited due to chemoresistance and its undesirable side effects. The combination of chemotherapeutic agents and natural compounds is an eff...
Adult Hippocampal Neurogenesis and Alzheimer's Disease: Novel Application of Mesenchymal Stem Cells and their Role in Hippocampal Neurogenesis [0.03%]
成体海马神经发生与阿尔茨海默病：间充质干细胞的新应用及其在海马区神经发生中的作用
Mahdi Noureddini,Saeid Bagheri-Mohammadi
Mahdi Noureddini
The neurogenesis can occur in two regions of the adult mammalian brain throughout the lifespan: the subgranular zone of the hippocampal dentate gyrus, and the subventricular zone of the lateral ventricle. The proliferation and maturation of...
PD-1, TIM-3, and LAG-3 Expression in T Cells in a Patient with Recurrent Ossifying Fibroma: A Case Report [0.03%]
程序性细胞死亡蛋白1、T细胞免疫球蛋白和黏膜分子3及淋巴激活基因3在成釉细胞纤维瘤复发患者T细胞中的表达：1例报告
Alejandro García-Muñoz,Nayeli Goreti Nieto-Velázquez,Gabriela Damian-Morales et al.
Alejandro García-Muñoz et al.
Central ossifying fibroma is a benign, slow-growing tumor of mesenchymal origin with a predilection for the mandibular premolar and molar areas. The immunophenotype of T cells involved in the antitumor response against this benign tumor is ...
Investigating Genetic Factors Contributing to Variable Expressivity of Class I 17p13.3 Microduplication [0.03%]
研究I型17p13.3微重复变异表达性的遗传因素
Giovanna Cantini Tolezano,Silvia Souza da Costa,Marília de Oliveira Scliar et al.
Giovanna Cantini Tolezano et al.
17p13.3 microduplications are rare copy number variations (CNVs) associated with variable phenotypes, including facial dysmorphism, developmental delay, intellectual disability, and autism. Typically, when a recognized pathogenic CNV is ide...