Metformin is a Novel Suppressor for Vimentin in Human Gastric Cancer Cell Line [0.03%]
二甲双胍通过抑制波形蛋白诱导人胃癌细胞衰老
Shiva Valaee,Mehdi Shamsara,Mohammad Mehdi Yaghoobi
Shiva Valaee
Vimentin, an intermediate filament of mesenchymal cells, is upregulated in epithelial-mesenchymal transition (EMT) and has a main role in cancer metastasis. As a new strategy to control metastatic outgrowth, EMT markers are generally inhibi...
Evaluation of FOXCUT, CCAT2, and HULC LncRNA Expression Levels and Apoptosis Induction by Sodium Butyrate in PC-3 and LNCAP Prostate Cancer Cell Lines [0.03%]
评估FOXCUT、CCAT2和HULC长链非编码RNA表达水平及NaB在PC-3和LNCaP前列腺癌细胞系中的促凋亡作用
Sanaz Kavousi,Seyed Ataollah Sadat Shandiz,Nastaran Asghari Moghaddam
Sanaz Kavousi
Sodium butyrate (NaBu) is a short-chain fatty acid acting as a histone deacetylase inhibitor, and has been shown to be a potential regulator of cancer cell death. This study aimed to evaluate the effect of NaBu on cell cycle control, apopto...
Role of mTOR Complex 1 Signaling Pathway in the Pathogenesis of Diabetes Complications; A Mini Review [0.03%]
mTOR复合体1信号通路在糖尿病并发症发病机制中的作用；迷你综述
Amir Yarahmadi,Negar Azarpira,Zohreh Mostafavi-Pour
Amir Yarahmadi
The mammalian target of rapamycin (mTOR) is an evolutionarily conserved serine/threonine-protein kinase that senses and combines various environmental signals to regulate the growth and homeostasis of human cells. This signaling pathway syn...
Curcumin in Combination with Other Adjunct Therapies for Brain Tumor Treatment: Existing Knowledge and Blueprint for Future Research [0.03%]
姜黄素联合其他辅助疗法治疗脑肿瘤：现有知识与未来研究蓝图
Kavita Peter,Santosh Kumar Kar,Ragini Gothalwal et al.
Kavita Peter et al.
Malignant brain tumors proliferate aggressively and have a debilitating outcome. Surgery followed by chemo-radiotherapy has been the standard procedure of care since 2005 but issues of therapeutic toxicity and relapse still remain unaddress...
The Relationship between rs534654 Polymorphism in TMEM165 Gene and Increased Risk of Bipolar Disorder Type 1 [0.03%]
TMEM165基因rs534654多态性与I型双相情感障碍发病风险增加的关系研究
Asmaolhosna Amini,Sara Sadat Aghabozorg Afjeh,Behzad Boshehri et al.
Asmaolhosna Amini et al.
Bipolar disorder (BD) is a major health care concern worldwide. There are some reports showing an association between genes and their variants involved in circadian rhythm; clock and clock related genes function and development of BD in pat...
Modulation of mRNA Expression of Monoacylglycerol Lipase, Diacylglycerol Lipase and Cannabinoid Receptor-1 in Mice Experimentally Infected with T. gondii [0.03%]
弓形虫实验感染小鼠单酰甘油脂肪酶、二酰甘油脂肪酶和 cannabinoid 体 1 mRNA 表达的调节作用研究
Sahar Rostami-Mansoor,Narges Kalantari,Tahmineh Gorgani-Firouzjaee et al.
Sahar Rostami-Mansoor et al.
Toxoplasma gondii, an obligate intracellular parasite, infects more than 30% of world's population. This parasite is considered to be neurotropic, and has high tropism for the central nervous system, and potentially induces cryptogenic epil...
The Role of Bone Marrow-Derived Mesenchymal Stromal Cells and Hesperidin in Ameliorating Nephrotoxicity Induced by Cisplatin in Male Wistar Rats [0.03%]
骨髓间充质基质细胞和辛弗林在减轻雄性Wistar大鼠顺铂诱导的肾毒性的中的作用研究
Khalid Mohamed Mazher,Osama Mohamed Ahmed,Hadeer Abdallah Sayed et al.
Khalid Mohamed Mazher et al.
Bone marrow-derived mesenchymal stromal cells (BM-MSCs) and antioxidants opened the way for many effective therapeutic experiments against damaged organs like kidneys. Nephrotoxicity is the main complication of chemotherapeutic drugs. There...
Altered mRNA Expression of Fucosyltransferases and Fucosidase Predicts Prognosis in Human Oral Carcinoma [0.03%]
岩藻糖转移酶和岩藻糖苷酶的mRNA表达变化预测人口腔鳞癌预后
Kruti Mehta,Kinjal Patel,Shashank Pandya et al.
Kruti Mehta et al.
Aberrant protein glycosylation is known to be associated with the development of various cancers. Although fucosylation is essential for normal biological functions, alterations in fucosylation are strongly implicated in cancer and increasi...
Mesenchymal Stem Cells cause Telomere Length Reduction of Molt-4 Cells via Caspase-3, BAD and P53 Apoptotic Pathway [0.03%]
间充质干细胞通过Caspase-3,BAD和P53凋亡通路导致Molt-4细胞端粒长度缩短
Hamid Reza Heidari,Ezzatollah Fathi,Soheila Montazersaheb et al.
Hamid Reza Heidari et al.
Mesenchymal stem cells (MSCs) as undifferentiated cells are specially considered in cell-based cancer therapy due to unique features such as multi-potency, pluripotency, and self-renewal. A multitude of cytokines secreted from MSCs are know...
Update on Safety and Efficacy of HPV Vaccines: Focus on Gardasil [0.03%]
HPV疫苗的安全性和有效性更新：重点关注Gardasil
Monica Soliman,Ololade Oredein,Crispin R Dass
Monica Soliman
The human papillomavirus (HPV) is a highly contagious and prevalent virus that is primarily sexually transmitted. The Gardasil® quadrivalent vaccine, the Cevarix® bivalent vaccine and the Gardasil® 9 nonavalent vaccine were developed to ...