Comparison of a Suggested Model of Fibrosis in Human Dermal Fibroblasts by Serum from Systemic Sclerosis Patients with Transforming Growth Factor β Induced in vitro Model [0.03%]
系统性硬皮病患者血清提出的纤维化模型与转化生长因子β诱导的体外模型在人真皮成纤维细胞中的比较研究
Elnaz Dadashzadeh,Marie Saghaeian Jazi,Nafiseh Abdolahi et al.
Elnaz Dadashzadeh et al.
Systemic sclerosis (SSc) is a chronic autoimmune disease, featuring fibrosis in multiple organs. The serum from SSc patients contain inflammatory mediators, contributing to SSc pathogenesis and could be used to develop cell culture models. ...
Knockdown of SOX12 Expression Induced Apoptotic Factors is Associated with TWIST1 and CTNNB1 Expression in Human Acute Myeloid Leukemia Cells [0.03%]
SOX12基因沉默通过与人类急性髓系白血病细胞中TWIST1和CTNNB1表达相互作用诱导凋亡相关因素的表达
Arezou Dabiri,Mohammadreza Sharifi,Akram Sarmadi
Arezou Dabiri
Recent improvements in molecular treatment and gene therapy led to discovering novel cancer remedies. Antisense LNA GapmeRs is a state-of-the-art molecular research field for diagnosing and treating various cancer types. Acute myeloid leuke...
Narendra Ichiputra Hariyanto,Edward Christopher Yo,Septelia Inawati Wanandi
Narendra Ichiputra Hariyanto
Cell signaling is a vital part of biological life. It helps coordinating various cellular processes including cell survival, cell growth, cell death, and cell interaction with the microenvironment and other cells. In general, cell signaling...
MicroRNA-145, Wnt3a, and Dab2 Genes Expression Changes of the Cardiomyocytes in Hypercholesterolemic Rats Exposed to the Aerobic Training [0.03%]
有氧运动对高胆固醇大鼠心肌细胞中MicroRNA-145、Wnt3a及Dab2基因表达的影响研究
Soran Heidari,Kamal Azizbeigi,Kaveh Bahmanpour
Soran Heidari
The current study aimed to investigate the effect of a 12-week endurance training (ET) on microRNA-145 (miR-145) changes and Wnt3a and Dab2 cardiomyocytes genes expression of hypercholesterolemic Wistar male rats. Thirty-two male Wistar rat...
Induction of Apoptosis in the U937 Cell Line Co-cultured with Adipose-derived Stem Cells Secreting Bone Morphogenetic Protein-4 [0.03%]
分泌骨形态发生蛋白-4的脂肪来源干细胞诱导U937细胞凋亡
Mostafa Ghorban Khan Tafreshi,Zohreh Mazaheri,Mansour Heidari et al.
Mostafa Ghorban Khan Tafreshi et al.
Transforming growth factor-beta (TGF-β) plays a significant role in tumorigenesis. MiR-181b is a multifunctional miRNA involved in numerous cellular processes, such as cell fate and cell invasion. This study aimed to examine whether the co...
The Role of PaFicT in Pseudomonas aeruginosa Persister Cell Formation [0.03%]
PaFicT在铜绿假单胞菌休眠细胞形成中的作用研究
Dawson Fogen
Dawson Fogen
The opportunistic pathogen Pseudomonas aeruginosa (Pa) is a major concern for immunocompromised and cystic fibrosis patients. Chronic lung infections caused by Pa are generally considered incurable, in part, due to the bacteria's ability to...
Long Non-coding RNA snaR Promotes Proliferation in EGFR Wild Type Non-Small Cell Lung Cancer Cells [0.03%]
长链非编码RNA snaR通过促进EGFR野生型肺腺癌细胞增殖促进肿瘤进展
Melika Ameli Mojarad,Mandana Ameli Mojarad,Alireza Pourmahdian
Melika Ameli Mojarad
Lung cancer is the second most common cancer and has high morbidity and mortality worldwide with non-small cell lung cancer (NSCLC) accounting for 85% of the cases. Over-expression of epidermal growth factor receptor (EGFR) has been clarifi...
Identification of Novel Insertions and Deletions in Haematopoietic Stem/Progenitor Cells in de novo Myelodysplastic Syndromes [0.03%]
新发骨髓增生异常综合征中造血干细胞/祖细胞中新插入和缺失的鉴定
Manoj Bandara,Hemali Goonasekera,Vajira Dissanayake
Manoj Bandara
Myelodysplastic Syndromes (MDS) are clonal haematological stem cell disorders. The molecular basis of MDS is heterogeneous and the molecular mechanisms underlying biology of this complex disorder are not fully understood. Genetic variations...
Oral Contraceptive Steroids Promote Papillary Thyroid Cancer Metastasis by Targeting Angiogenesis and Epithelial-Mesenchymal Transition [0.03%]
口服避孕药类固醇通过靶向血管生成和上皮间质转化促进乳头状甲状腺癌转移
Mohammad Hossein Dehghan,Mohammad Reza Ashrafi,Mehdi Hedayati et al.
Mohammad Hossein Dehghan et al.
Thyroid cancer is the most prevalent type of endocrine malignancy with the highest incidence rate among women under 45 years old. Ethinylestradiol (EE) and levonorgestrel (LNG) are two steroid components of low-dose oral contraceptives used...
Quercetin Arrests in G2 phase, Upregulates INXS LncRNA and Downregulates UCA1 LncRNA in MCF-7 Cells [0.03%]
槲皮素使MCF-7细胞G2期停滞、上调INXS lncRNA及下调UCA1 lncRNA
Fatemeh Rezaie,Mohammad Javad Mokhtari,Mehdi Kalani
Fatemeh Rezaie
One of the most prevalent malignancies, which have severe effects on women's health, is breast cancer. Quercetin, a flavonoid found in vegetables, tea, and fruits, is known to have bioactive properties, such as anti-inflammatory, anti-oxida...