Improvement of Corneal Nerve Regeneration in Diabetic Rats Using Wharton's Jelly-Derived Mesenchymal Stem Cells and their Conditioned Medium [0.03%]
人脐带基质干细胞及其培养液对糖尿病大鼠角膜神经再生的影响
Pitra Ariesta Shinta Dewi,Ratna Sitompul,Jeanne Adiwinata Pawitan et al.
Pitra Ariesta Shinta Dewi et al.
To investigate the efficacy of Wharton's jelly mesenchymal stem cells (WJSCs) and their conditioned medium (CM) for corneal nerve regeneration in rats with diabetic keratopathy. Streptozotocin (STZ)-induced male diabetic (DM) rats (250-300 ...
Capsaicin Alters the Expression of Genetic and Epigenetic Molecules In Hepatocellular Carcinoma Cell [0.03%]
辣椒素通过遗传和表观遗传机制对肝细胞癌进行治疗及其潜在分子机制的研究
Beren Ates,Çağrı Öner,Zeynep Akbulut et al.
Beren Ates et al.
Capsaicin is a natural product which is extracted from pepper and has the potential to be used in cancer treatment because of its anti- proliferative effects. The aim of the study was to determine the effect of capsaicin on the hepatocellul...
Applying Vasopressin-Pre-Conditioned Human Adipose Mesenchymal Stem Cells Improves Heart Condition after Transplantation into Infarcted Myocardium [0.03%]
血管加压素预处理的人体脂肪间充质干细胞移植入心肌梗死区可改善心脏状况
Shakiba Nasiri Boroujeni,Farzaneh Chehelcheraghi,Mojtaba Khaksarian et al.
Shakiba Nasiri Boroujeni et al.
Transplantation of H-AdMSCs may improve heart function after MI. AVP is a neurohypophyseal hormone that reduces cardiovascular damage. This study investigated the role of AVP preconditioning in the survival of MSCs and their effect on myoca...
Evaluation of the Effect of Radiotherapy on CCL5/miR-214 -3p/MALAT1 Genes Expression in Blood Samples of Breast Cancer Patients [0.03%]
放射治疗对乳腺癌患者血液样本中CCL5/miR-214-3p/MALAT1基因表达影响的评估
Fazlollah Shokri,Hossein Mozdarani,Mir Davood Omrani
Fazlollah Shokri
Current cancer therapies include chemotherapy, radiation therapy, immunotherapy, and surgery. Despite these treatment methods, a major point in cancer treatment is early detection. RNAs (mRNA, miRNAs, and LncRNA) can be used as markers to i...
Current Perspectives and Future Prospects of mRNA Vaccines against Viral Diseases: A Brief Review [0.03%]
针对病毒性疾病的mRNA疫苗的现状和未来展望：综述
Vasavi Koppu,Deepa Poloju,Bhavani Puvvala et al.
Vasavi Koppu et al.
The mRNA vaccines replace our conventional vaccines (live-attenuated and inactivated vaccines) due to their high safety, efficacy, potency and low cost for their manufacturing. Since these many years, the use of these mRNA vaccines has been...
Increased Expression of Tight Junction Proteins and Blood-Brain Barrier Integrity in MCAO Rats Following Injection of miR-149-5p [0.03%]
注射miR-149-5p对MCAO大鼠血脑屏障完整性及紧密连接蛋白表达的影响
Meysam Forouzandeh,Hossein Mostafavi,Elham Ghasemloo et al.
Meysam Forouzandeh et al.
Cerebral ischemia is a common neurodegenerative disease in which damage to the blood-brain barrier (BBB) is the main consequence. In cerebral ischemia, the level of miR-149-5p and tight junction proteins are decreased, while the level of Ca...
Vitexin Induces Apoptosis in MCF-7 Breast Cancer Cells through the Regulation of Specific miRNAs Expression [0.03%]
垂藤黄素通过调节特定microRNA的表达诱导MCF-7乳腺癌细胞凋亡
Reza Najafipour,Abdol Mabood Momeni,Yousef Mirmazloomi et al.
Reza Najafipour et al.
In this research, we investigated microRNAs (miRNAs) expression profile in MCF-7 breast cancer cell line which treated with 150 µM vitexin. Profiling of miRNAs expression was performed using TaqMan MiRNA Array. Apoptosis was analyzed by fl...
hsa-miR-508-5p as a New Potential Player in Intervertebral Disc Degeneration [0.03%]
新型内源性microRNA hsa-miR-508-5p参与椎间盘退变作用机制的研究
Akram Gholipour,Mahshid Malakootian,Maziar Oveisee
Akram Gholipour
Intervertebral disc degeneration (IDD) is widely known as the principal cause of low back pain, diminishing patients' quality of life and imposing a huge economic burden on healthcare systems worldwide. However, the underlying mechanisms of...
Nrf2 rs6721961 and Oxidative Stress in Preeclampsia: Association with the Risk of Preeclampsia and Early-Onset Preeclampsia [0.03%]
NRF2基因rs6721961多态性与子痫前期易感性和早期发病的相关性研究
Fatemeh Khadir,Zohreh Rahimi,Azita Ghanbarpour et al.
Fatemeh Khadir et al.
Preeclampsia as a multifactor hypertensive disorder of pregnancy is associated with enhanced placental oxidative stress. The Keap1-Nrf2 pathway protects cells against oxidative stress. We examined the possible association between the Nrf2 v...
Novel Variant Identified in the Enhancer Region of Host Transcription Factor, BRN3A, is a Significant Risk Factor for HPV-Induced Uterine Cervix Cancer [0.03%]
宿主转录因子BRN3A增强子区的新变异体是HPV诱导的子宫颈癌的风险因素
Anand Prakash,Biswa Pratim Das Purkayastha,Shikha Srivastava et al.
Anand Prakash et al.
Among the HPV-mediated cervical cancers, cellular factor BRN3A has gained considerable attention due to its role in promoting an anti-apoptotic cellular environment and in facilitating epitheliotropic transformations of the host. The majori...