Lactoferrin and Activated Protein C: Potential Role in Prevention of Cancer Progression and Recurrence [0.03%]
乳铁蛋白和活化蛋白C在预防癌症进展和复发中的潜在作用
Nahid Akhtar,Atif Khurshid Wani,Musamey Jan et al.
Nahid Akhtar et al.
Existing therapeutic interventions for controlling cancer are limited and associated with side effects. Furthermore, the recurrence of cancer poses a significant challenge to the cure of cancer. Therefore, avenues are wanted to find novel t...
Isolation, Identification and Screening of Saharan Actinomycete Strain Streptomyces fimbriatus AC31 Endowed with Antimicrobial Activity [0.03%]
分离鉴定并筛选具有抗菌活性的撒哈拉链霉菌(SSF)菌株AC31
Omar Khirennas,Slimane Mokrani,Belkacem Behira et al.
Omar Khirennas et al.
The increasing global public health concern of antimicrobial resistance (AMR) necessitates exploration of natural antimicrobial agents as potential alternatives. This study aimed to investigate antimicrobial activities of Saharan actinomyce...
Prenatal Diagnosis of Triploidy in Fetus with Unexpected Chromosomal Translocation of Maternal Origin [0.03%]
母源染色体意外易位胎儿的三倍体产前诊断
Ajinkya Jadhav,Yamini Jadhav,Vidya Bhairi et al.
Ajinkya Jadhav et al.
Triploidy is a lethal chromosomal abnormality. Fetuses with triploid condition have a tendency to die in early conception and very few survive to term. In this study, we report the prenatal diagnosis of fetal triploidy with unexpected chrom...
Evaluating the Differential Expression of miR-146a, miR-222, and miR-9 in Matched Serum and Follicular Fluid of Polycystic Ovary Syndrome Patients: Profiling and Predictive Value [0.03%]
多囊卵巢综合征患者匹配血清和卵泡液中miR-146a、miR-222和miR-9的差异表达:谱型分析及预测价值
Zhale Ashrafnezhad,Mohammad Naji,Ashraf Aleyasin et al.
Zhale Ashrafnezhad et al.
Polycystic ovary syndrome (PCOS) is the most prevalent endocrine disorder of women in reproductive age with significant effects on reproductive and metabolic functions. Many molecular players may be involved in PCOS pathology; however, miRN...
Evaluation of miR-330-3p and BMI1 Expression in Colorectal Cancer Patients, Healthy Adjacent Tissues, and Polypoid Adenomatous Lesions [0.03%]
评估结直肠癌患者、健康邻近组织和腺瘤样病变中miR-330-3p和BMI1的表达
Parviz Basiri,Saeid Afshar,Razieh Amini et al.
Parviz Basiri et al.
MicroRNAs (miRNAs) have emerged as essential gene expression regulators associated with human diseases such as colorectal cancer (CRC). The purpose of this study was to evaluate the expression of miR-330-3p and its target gene BMI1 in tissu...
Exploring VEGF-Linked Pathways: Investigating Multiple miRNAs for Their Therapeutic Potential in Angiogenesis Targets and as Biomarkers in Recurrent Glioblastoma Multiforme [0.03%]
探索VEGF相关通路:研究多个miRNA作为复发性多形性胶质母细胞瘤血管生成靶点的治疗潜力及其生物标志物的作用
Morteza Hadizadeh,Ramin Soltani,Taimour Langaee et al.
Morteza Hadizadeh et al.
Alternative pathways frequently operate as the origins of resistance to drugs that block the vascular endothelial growth factor (VEGF) pathway. To find possible therapeutic targets and indicators, this study explored the VEGF pathway and ho...
Endothelin-1 Induced Phosphorylation of Caveolin-1 and Smad2C in Human Vascular Smooth Muscle Cells: Role of NADPH Oxidases, c-Abl, and Caveolae Integrity in TGF-β Receptor Transactivation [0.03%]
内皮素-1诱导的人血管平滑肌细胞上皮蛋白-1和Smad2/3磷酸化:NADPH氧化酶、c-Abl及微坑完整性在TGF-β受体转激活中的作用
Mahsa Hosseinipour,Mojtaba Rashidi,Faezeh Seif et al.
Mahsa Hosseinipour et al.
Caveolin-1(Cav-1) is one of the most important components of caveolae in the cell membrane, which plays an important role in cell signaling transduction, such as EGFR and TGF-β receptor transactivation. The purpose of this study was to eva...
Epstein-Barr Virus Nuclear Antigen 1 Increases the Expression of Viral Oncogenes and Cellular Genes in the HeLa Cell Line [0.03%]
EB病毒核抗原1在HeLa细胞系中增加病毒癌基因和细胞基因的表达
Amir Hossein Alipour,Seyed Mohammad Ali Hashemi,Afagh Moattari et al.
Amir Hossein Alipour et al.
Epstein-Barr virus (EBV) represents one of the most important viral carcinogens. EBV nuclear antigen-1 (EBNA1) can induce the expression of different cellular and viral genes. In this study, we evaluated the EBNA1 effects on the expression ...
Preparation and Characterization of Novel Schiff Base Derived From 4-Nitro Benzaldehyde and Its Cytotoxic Activities [0.03%]
由对硝基苯甲醛衍生新型希夫碱的制备及其抗细胞毒性研究
Rana Hassan Abdul Majeed,Hanaa Ali Hussein,Mohd Azmuddin Abdullah
Rana Hassan Abdul Majeed
Normal drugs exhibit activities against both normal and cancer cells. Furthermore, cancer cells may develop resistance to these drugs that alternative treatment must be explored. The main objective of this study was to examine the anticance...
FN14 mRNA Expression Correlates with an Increased Number of Veins during Angiogenesis in the Process of Liver Fibrosis [0.03%]
FN14 mRNA表达与肝纤维化过程血管生成中静脉数量增加相关性研究
Elena I Lebedeva,Andrei S Babenka,Pelin Hastemir et al.
Elena I Lebedeva et al.
In this study, we hypothesize that angiogenesis of special hepatic vessels such as sinusoid capillaries or veins is closely associated with increasing production of connective tissue in fibrogenesis. Thirty-six male Wistar rats were induced...