Contiguous Gene Deletion Involving COL4A1 and COL4A2 in a Patient with Thin Basement Membrane Nephropathy: A Case Report [0.03%]
COL4A1和COL4A2基因串联缺失与薄基底膜肾病的关系：病例报告
Marc Henein,Felicia Russo,Chantal Bernard et al.
Marc Henein et al.
Introduction: Type IV collagen trimers are major structural components of the kidney glomerulus and tubules. Several loss-of-function COL4A1 and COL4A2 variants have been reported to cause cerebral small vessel disease. H...
Case Reports
Nephron. 2025 Nov 21:1-15. DOI:10.1159/000549595 2025
Vetle Saastad,Ludvig Balteskard Rinde,Inger Therese Enoksen et al.
Vetle Saastad et al.
Background There are considerable sex and gender differences in the epidemiology of chronic kidney disease (CKD), with CKD stage 3, defined as a glomerular filtration rate (GFR) below 60, being more prevalent in women. This raises questions...
Review
Nephron. 2025 Nov 18:1-8. DOI:10.1159/000549078 2025
Navigating disparities and overcoming barriers to access Diabetic Kidney Disease therapies: A proposed multifactorial approach [0.03%]
应对糖尿病肾病治疗障碍的多因素方法克服获取疗法的障碍
Romela Petrosyan,A Enrique Caballero,Tracey L Henry et al.
Romela Petrosyan et al.
Background: Diabetic Kidney Disease (DKD) is a serious complication arising from long-term diabetes, disproportionately affecting historically marginalized populations, such as racial and ethnic minority groups, populatio...
Review
Nephron. 2025 Nov 13:1-18. DOI:10.1159/000548904 2025
Lactitol-Induced Acute Kidney Injury with Oxalate Nephropathy: A Case Report [0.03%]
乳itol致急性肾损伤合并草酸 nephropathy 1 例报告
Mijie Guan,Haofei Hu,Haiying Song et al.
Mijie Guan et al.
Introduction: Oxalate nephropathy, characterized by calcium oxalate crystal deposition in renal tissue, represents an underrecognized etiology of acute and chronic kidney injury. Secondary hyperoxaluria can emerge from di...
Case Reports
Nephron. 2025 Nov 13:1-13. DOI:10.1159/000548254 2025
Abnormal Right Ventricular to Pulmonary Artery Coupling in Patients with End-Stage Kidney Disease and Normalization After Renal Transplantation: An Observational Study [0.03%]
终末期肾病患者右心室与肺动脉耦联异常及肾移植后的正常化：一项观察性研究
Rengin Çetin Güvenç,Tolga Sinan Güvenç,Ezgi Sude Karakaya et al.
Rengin Çetin Güvenç et al.
Background: Pulmonary hypertension and right ventricular (RV) dysfunction are associated with an increase in mortality and worse prognosis in patients with end-stage kidney disease (ESKD), but pathophysiologic mechanisms ...
Role of mitophagy in ischemia-reperfusion renal injury: new insights from bioinformatics analysis [0.03%]
生物信息学分析揭示线粒体自噬在线 ischemia-reperfusion 肾损伤中的作用：新见解
Huanjie Zhou,Qionghui Huang,Aoran Huang et al.
Huanjie Zhou et al.
Introduction: Mitophagy is central to acute kidney injury (AKI) pathogenesis. Elucidating its molecular interplay with AKI is crucial for novel therapeutics. ...
Transcriptomic Insights into Polyomavirus Nephropathy in Kidney Transplants: Evaluating the Utility of the B-HOT Panel [0.03%]
移植肾多瘤病毒感染的转录组学见解：评估B-HOT检测 panel 的实用性
Kohta Hatanaka,Sari Iwasaki,Shugo Tanaka et al.
Kohta Hatanaka et al.
Background: Polyomavirus nephropathy (PyVN) is a significant complication following kidney transplantation, characterized by tubulointerstitial inflammation that mimics T cell-mediated rejection (TCMR). The Banff Human Or...
Marta Raposo
Marta Raposo
Published Erratum
Nephron. 2025 Oct 20:1. DOI:10.1159/000548396 2025
Prospects for Artificial Intelligence-based Pathological Diagnosis of Renal Transplant Biopsy [0.03%]
基于人工智能的肾移植活检病理诊断展望
Kazuhiro Iwadoh,Makoto Tonsho
Kazuhiro Iwadoh
Background: Artificial intelligence, initiated in the 1950s, has matured after two setbacks into Deep Neural Networks (DNNs) and Large Language Models (LLMs). Key drivers of success were the adoption of nonlinear models a...
Review
Nephron. 2025 Oct 18:1-11. DOI:10.1159/000549067 2025
Association of Monocyte-Lymphocyte Ratio with Cardiovascular Events and All-Cause Mortality in Patients Undergoing Hemodialysis: A Prospective Cohort Study [0.03%]
单核细胞-淋巴细胞比率与血液透析患者心血管事件和全因死亡率的相关性：一项前瞻性队列研究
Yamini Mallisetty,Ahmed Kabeil,Cameron Jackson Bergeron et al.
Yamini Mallisetty et al.
Introduction Elevated monocyte to lymphocyte ratio (MLR) represents a pro-inflammatory immune microenvironment and has been associated with poor clinical outcomes such as cardiovascular disease. However, little is known about its associatio...