The impact of air pollution on kidney function: A two-sample Mendelian randomization study [0.03%]
空气污染对肾功能影响的孟德尔随机化研究
Hao Wu,Zixian Yu,Ziyun Yu et al.
Hao Wu et al.
Background: Chronic kidney disease (CKD) is a growing public health problem, resulting in significant morbidity and mortality. The relationship between air pollution (particulate matter (PM)2.5, PM2.5-10, and PM10, Nitrog...
Effects of N-Acetyl-L-Cysteine on the progression of kidney dysfunction in Acadian variant Fanconi syndrome: a case series [0.03%]
N-乙酰半胱氨酸对Acadian变异型Fanconi综合征患者肾功能进展影响的病例系列研究
Mohammad Al-Qadi,Caroline Jose,Jeffrey Gaudet et al.
Mohammad Al-Qadi et al.
Introduction Acadian variant Fanconi syndrome (AVFS) is an autosomal recessive disease caused by a mutation in the NDUFAF6 gene which results in mitochondrial dysfunction and oxidative damage to the kidneys. It presents as a slowly progress...
Case Reports
Nephron. 2026 Jan 19:1-10. DOI:10.1159/000549747 2026
CYSTIC FIBROSIS BEYOND CHILDHOOD: A CASE REPORT OF RECURRENT HEAT-INDUCED ELECTROLYTE DISTURBANCES UNMASKING A LATE DIAGNOSIS [0.03%]
囊性纤维化不仅仅是儿童病——一例因高温诱发的电解质紊乱导致的迟发诊断病例报告
Deborah Roldán,Mariana León-Póo,Eva López-Melero et al.
Deborah Roldán et al.
Introduction: Cystic fibrosis (CF) is an autosomal recessive genetic disorder caused by pathogenic variants in the CFTR gene, leading to impaired chloride and bicarbonate transport across epithelial tissues. While typical...
Case Reports
Nephron. 2026 Jan 16:1-8. DOI:10.1159/000550562 2026
Metabolic demand, renal mass and GFR changes in men and women: Lessons from living kidney donors and recipients [0.03%]
人体代谢需求、肾重量及肾小球滤过率在男性和女性中的变化：来自活体肾脏捐献者与受捐者的启示
Ana González-Rinnea,Esteban Porrini
Ana González-Rinnea
Background: The determinants of glomerular filtration rate (GFR) and its changes over time are multiple and diverse. Nephron endowment is the starting point for GFR. Low renal endowment due to maternal undernutrition or p...
Review
Nephron. 2026 Jan 13:1-14. DOI:10.1159/000549797 2026
Association between anti-nephrin antibodies and podocytopathies: a systematic review and meta-analysis [0.03%]
抗肾小球内皮细胞抗体与肾小球病关联的系统性回顾和元分析
Ju&#x;an Wang,Jinglei Chen,Zige Chen et al.
Ju&#x;an Wang et al.
Objective: Explore the positive rate of anti-nephrin antibodies in various podocytopathies and their relationship with the clinical characteristics and outcomes of podocytopathies. ...
Integrated sTim-3 and PLA2R-Ab levels improve risk stratification in PLA2R-positive membranous nephropathy [0.03%]
联合检测sTIM-3和PLA2R-Ab水平可改善PLA2R阳性膜性肾病患者的危险分层
Tianyu Zheng,Yuanyuan Du,Xuanli Tang et al.
Tianyu Zheng et al.
Background: The utility of M-type phospholipase A2 receptor antibody (PLA2R-Ab) for risk stratification in membranous nephropathy (MN) remains suboptimal, while soluble T-cell immunoglobulin and mucin-domain containing-3 ...
Mitochondria to the rescue: organelle trafficking in renal health and disease [0.03%]
线粒体救援：肾脏健康和疾病下的器官运输现象
Luca Perico,Giuseppe Remuzzi,Ariela Benigni
Luca Perico
Background: Mitochondria are central regulators of cellular metabolism, redox signaling, and apoptosis. Their dysfunction plays a pivotal role in the pathogenesis of kidney diseases, including acute kidney injury and diab...
Review
Nephron. 2025 Dec 19:1-18. DOI:10.1159/000550092 2025
Successful Living Kidney Donation from Heterozygous Carrier Parents to Siblings with Coenzyme Q8B Nephropathy: Two Case Series [0.03%]
成功地将肾脏从杂合子供者父母捐献给CoQ8B型肾病患者的两个案例系列研究
Keisuke Morita,Risa Nakanishi,Kikuno Ogura et al.
Keisuke Morita et al.
Introduction: Coenzyme Q8B (COQ8B) nephropathy is an autosomal recessive hereditary disorder caused by primary coenzyme Q10 (CoQ10) deficiency. It manifests as a genetic steroid-resistant nephrotic syndrome (SRNS), typica...
Case Reports
Nephron. 2025 Dec 18:1-17. DOI:10.1159/000550059 2025
Bench to Bedside: Translating Discoveries to Clinical Care in Kidney Disease [0.03%]
从实验室到临床：肾脏疾病研究的临床转化
Katharine Epler,Dana Y Fuhrman,Sudarshan Hebbar et al.
Katharine Epler et al.
Acute kidney injury (AKI) pathophysiology and repair are heterogenous processes, and clinical outcomes are difficult to predict. As a result, promising treatments in preclinical models have failed to translate to human subjects, and treatme...
Review
Nephron. 2025 Dec 17:1-13. DOI:10.1159/000550091 2025
Association Between Hemoglobin-to-red Cell Distribution Width Ratio and Left Ventricular Hypertrophy in Non-Dialysis CKD Stage 3-5 Patients: A Cross-Sectional Study [0.03%]
血红蛋白/红细胞分布宽度比值与非透析CKD三期至五期患者左心室肥厚的关系：一项横断面研究
Li Wang,Lin Zhang,Fangfang Xiang et al.
Li Wang et al.
Introduction: Left ventricular hypertrophy (LVH) is a common cardiovascular complication in chronic kidney disease (CKD), driven by anemia and nutritional deficiencies. The hemoglobin-to-red cell distribution width ratio ...