The Mechanism of the NLRP3 Inflammasome Activation and Pathogenic Implication in the Pathogenesis of Gout [0.03%]
NLRP3炎症小体活化的机制及其在痛风发病中的病理意义
Seong-Kyu Kim
Seong-Kyu Kim
The NACHT, LRR, and PYD-domains-containing protein 3 (NLRP3) inflammasome is an intracellular multi-protein signaling platform that is activated by cytosolic pattern-recognition receptors such as NLRs against endogenous and exogenous pathog...
Hyun Ah Kim
Hyun Ah Kim
Osteoarthritis (OA) is the most common form of arthritis and is a growing public health concern in the aging society. In rapidly aging societies such as in Korea, the increasing prevalence of OA may present serious new health issues. There ...
Pediatric Sarcoidosis Misdiagnosed as Hepatosplenic Abscesses: A Case Report and Review [0.03%]
误诊为肝脾脓肿的儿童肉芽肿性肺病一例报告及文献复习
Su Min Lee,Hyungwook Choi,Sungmin Lim et al.
Su Min Lee et al.
Sarcoidosis is a systemic granulomatous disorder of unknown etiology characterized by granuloma formation. Due to the limited incidence of sarcoidosis in pediatric patients, little is known about the clinical course of this disease. A combi...
Jisoo Lee,Yoon-Kyoung Sung,Myeung-Su Lee et al.
Jisoo Lee et al.
Time-integrated Cumulative Parameters Predictive of Radiographic Progression of Rheumatoid Arthritis: Real-world Data From a Prospective Single-center Cohort [0.03%]
预测放射学进展的累积时间综合参数：前瞻性单中心队列的真实世界数据
Youngjae Park,Mei-Ling Li,Ji-Won Kim et al.
Youngjae Park et al.
Objective: With many chronic inflammatory diseases, outcomes are determined by assessing both disease activity at presentation and cumulative activity over time. Here, we investigated whether cumulative activity better re...
A Case of Macrophage Activation Syndrome During the Treatment of Adult-onset Still's Disease With Tocilizumab [0.03%]
托珠雅治疗成人Still病并发巨噬细胞活化综合征1例
Ju Ho Lee,You-Jung Ha,Eun Ha Kang et al.
Ju Ho Lee et al.
Macrophage activation syndrome (MAS) is a fatal complication of adult-onset Still's disease (AOSD). Although anti-cytokine agents have been recommended for refractory AOSD or complicated with MAS, MAS cases have been rarely reported during ...
Evaluation of Serum Matrix Metalloproteinase-3 as an Objective Indicator for the Disease Activity in Rheumatoid Arthritis Patients Treated With Methotrexate Versus Tocilizumab: 24-week Results From a Prospective Randomized Controlled Study [0.03%]
评估类风湿关节炎患者使用甲氨蝶呤与托珠单抗治疗的疾病活动性的客观指标血清基质金属蛋白酶-3：一项前瞻性随机对照研究的24周结果
Jina Yeo,Han Joo Baek,Yeong Wook Song et al.
Jina Yeo et al.
Objective: This study aims to evaluate the change in serum metalloproteinase-3 (MMP-3) following the management of active rheumatoid arthritis (RA) and define the relationships between MMP-3 and disease activity indices. ...
Recent Advances in Basic and Clinical Aspects of Rheumatoid Arthritis-associated Interstitial Lung Diseases [0.03%]
类风湿关节炎相关间质性肺疾病的临床和基础研究新进展
Hanna Lee,Sang-Il Lee,Hyun-Ok Kim
Hanna Lee
Rheumatoid arthritis (RA) is a common autoimmune disease that mainly affects the joints and systemic organs, such as the skin, eyes, heart, gastrointestinal tract, and lungs. In particular, among various pulmonary involvements, interstitial...
Idiopathic Inflammatory Arthritis in the Auditory Canal in a Patient With Hearing Impairment: A Case Report and Literature Review [0.03%]
听障患者耳道特发性炎性关节病1例报告及文献复习
So Hye Nam,Gi Hwan Kim,Hong Ju Park et al.
So Hye Nam et al.
Inflammatory arthritis can affect the auditory system during the disease course. Although most cases show asymptomatic hearing impairment, it can result in hearing loss. Here we describe the case of a 70-year-old female with hearing impairm...
Assessment on Treatments With Conventional Synthetic Disease-modifying Drugs Before Initiating Biologics in Patients With Rheumatoid Arthritis in Korea: A Population-based Study [0.03%]
韩国类风湿关节炎患者使用生物制剂治疗前采用常规合成疾病改善药物的评估：基于人口的队列研究
Min Jung Kim,Eun Hye Park,Anna Shin et al.
Min Jung Kim et al.
Objective: To assess pre-biologic treatments with conventional synthetic disease-modifying drugs (csDMARDs) prior to biologics initiation among patients with rheumatoid arthritis (RA). ...