Protective effect of menthol against diethylnitrosamine-induced hepatocellular carcinoma in mice by downregulating CTNNB1 and HIF-1α [0.03%]
薄荷素通过下调CTNNB1和HIF-1α对N-亚硝基二乙胺所致小鼠肝细胞癌的保护作用
Zahra Mollaei,Masoumeh Asle-Rousta,Golnaz Asaadi Tehrani
Zahra Mollaei
Objective: This study examined the impact of menthol, a natural monoterpene, on diethylnitrosamine (DEN)-induced molecular and histopathological changes in the livers of male mice. ...
The hydroalcoholic extract of Nasturtium officinale protectively inhibits apoptotic and inflammatory pathways in hepato- and nephrotoxicity: An in vivo study [0.03%]
蔊达菜水醇提物对肝肾毒性损伤的保护作用：体内实验研究
Sevil Soudkhah,Sahar Keyghobadi,Amir Shadboorestan et al.
Sevil Soudkhah et al.
Objective: Nasturtium officinale (N. officinale (NO)) has been widely used in traditional medicine. This study investigates the protective effects of NO against hepatic and renal damage induced by CCl4 and gentamicin, res...
The effects of an Aloe-based polyherbal formulation on fertility parameters in male rats [0.03%]
基于芦荟的多药配方对雄性大鼠生育参数的影响
Fahimeh Safaeinejad,Mojgan Tansaz,Farkhonde Sarhaddi et al.
Fahimeh Safaeinejad et al.
Objective: Aloe dry juice as a purgative agent is widely used in phytotherapy. In Iranian traditional medicine to decrease Aloe side effects, some plants are added, and this polyherbal formulation is named "Ayarij-e-Faiqr...
Effects of sumac aqueous extract along with eating and drinking modification on functional dyspepsia symptoms in comparison with omeprazole: An open-label, randomized, controlled clinical trial [0.03%]
与奥美拉唑相比，食用漆树属植物水提取物结合饮食饮水方式改善对功能性消化不良症状的影响：一项开放标签、随机对照临床试验
Mahdi Saravani,Zahra Memariani,Nasser Behnampour et al.
Mahdi Saravani et al.
Objective: Functional dyspepsia (FD), a common gastrointestinal problem. The aim of the study was to evaluate the influence of Rhus coriaria L. (sumac) on FD. ...
Investigating the potential effects of olive leaves and ginger rhizome extracts on kidney and liver functions in alloxan-induced diabetic rats [0.03%]
研究橄榄叶和生姜提取物对链佐星诱导的糖尿病大鼠肾脏和肝脏功能潜在影响的研究
Shatha Alshaer,Mohammad A A Al-Najjar,Feras Darwish El-Hajji et al.
Shatha Alshaer et al.
Objective: Although there are many drugs on the shelves of pharmacies to manage diabetes mellitus (DM), many people around the world still use herbal preparations to treat it. This study investigated the effect of an aque...
The effects of saffron supplementation on inflammatory factors and clinical outcomes in sepsis patients admitted to the intensive care unit (ICU): Study protocol for a double-blind randomized controlled clinical trial [0.03%]
藏红花补充剂对重症监护病房收治的脓毒症患者炎症因子和临床结果影响的双盲随机对照试验研究方案
Shirin Hassanizadeh,Babak Alikiaii,Mohammad Hossein Rouhani et al.
Shirin Hassanizadeh et al.
Objective: Research studies have examined saffron's effects on inflammation, infection, and oxidative stress. Nevertheless, the effects of saffron on sepsis patients in the intensive care units (ICUs) have not yet been st...
Neuroprotective effects of hesperidin and auraptene on 6-hydroxydopamine-induced neurodegeneration in SH-SY5Y cells [0.03%]
芸香素和长叶澳洲芹素通过自噬对6-羟基多巴胺诱导的神经毒性损伤发挥保护作用
Malihe Mehrparvar Tajoddini,Elaheh Gheybi,Mehdi Rostami et al.
Malihe Mehrparvar Tajoddini et al.
Objective: Destruction of dopaminergic neurons causes diseases. Various compounds with neuroprotective and antioxidant properties have been identified, including Hesperidin (HES) and Auraptene (AUR). We aimed in this stud...
RAS/RAF/MEK/MAPK signaling pathway as a therapeutic target in breast cancer: Emphasis on a novel carrier for tamoxifen and digestion behaviors [0.03%]
乳腺癌治疗中的RAS/RAF/MEK/MAPK信号通路：托瑞米芬的新载体及消化行为值得关注
Niloofar Mansouri,Melika Daneshgar,Farzaneh Khojasteh et al.
Niloofar Mansouri et al.
Objective: This research attempted to increase the bioactivity and solubility and reduce the side effects of Tamoxifen (TMX) by using the cellulose nanocrystals (CNCs) extracted from walnut shells as a carrier and studied...
Antidiabetic effects of Peganum harmala seed extract on streptozotocin-induced diabetes in rats [0.03%]
胡蔓藤籽提取物对链脲佐菌素致糖尿病大鼠的降糖作用
Mozafar Khazaei,Mohammadali Meskaraf-Asadabadi,Elham Ghanbari et al.
Mozafar Khazaei et al.
Objective: Diabetes, a chronic metabolic disease, has many complex complications and an increasing prevalence in various societies. Despite conventional drug treatments and limited surgical and tissue transplant methods, ...
Preventive and therapeutic effects of Nasturtium officinale hydroalcoholic extract on cyclophosphamide-induced testicular toxicity in rats [0.03%]
蔊菜醇提物对环磷酰胺致大鼠睾丸毒性的预防和治疗作用研究
Hamideh Aboutalebi,Fatemeh Alipour,Alireza Ebrahimzadeh-Bideskan
Hamideh Aboutalebi
Objective: Cyclophosphamide (Cy) as an alkylating chemotherapeutic agent with broad-spectrum efficacy in cancer treatment. Despite its wide spectrum of clinical usage, off-target multiple organ toxicity such as sperm and ...