Antioxidant, anti-inflammatory and cytoprotective effects of crocin, a bioactive constituent of saffron, in Alzheimer's and Parkinson's diseases with a focus on molecular mechanisms: A systematic review [0.03%]
藏红花生物活性成分藏红素的抗氧化、抗炎和细胞保护作用及其在阿尔茨海默病和帕金森病中的分子机制:系统性综述
Zahra Tayarani-Najaran,Elham Hadipour,Shirin Ramazani et al.
Zahra Tayarani-Najaran et al.
Objective: This study assessed the neuroprotective effects of crocin one of the main bioactive compounds of saffron, in Alzheimer's and Parkinson's diseases, by focusing on its anti-oxidative, anti-inflammatory, and cytop...
Wortmannin exhibits anticancer activity in oral cancer cell line by targeting PI3K, AKT and mTOR pathway [0.03%]
wortmannin通过作用于PI3K,AKT和mTOR途径在口腔癌细胞系中表现出抗癌活性
Gauri Kumbhar,Poonam Suryawanshi,Vaibhav Ladke
Gauri Kumbhar
Objective: Although the molecular mechanism by which wortmannin exerts its anticancer properties in solid tumors is not fully understood, particularly in the context of oral cancer where research is scarce, this study see...
Comparison of Hibiscus sabdariffa L. extract and hydrochlorothiazide as adjuncts to Valsartan in managing hypertension in type 2 diabetic nephropathy: A randomized clinical trial [0.03%]
罗布斯塔红茶提取物与氯噻嗪作为缬沙坦辅剂治疗2型糖尿病肾病高血压的比较:一项随机临床试验
Maryam Kiani,Hassan Mirzaei,Ayesheh Enayati et al.
Maryam Kiani et al.
Objective: The effects of Hibiscus sabdariffa L. extract (HSE) as a supplemental therapy with valsartan for type 2 diabetic patients with nephropathy and its underlying biological functions were investigated in this study...
Possible therapeutic effects of Plantago major in women with high menstrual bleeding: A systematic review of randomized clinical trials [0.03%]
蒲公英治疗月经过多的潜在疗效:随机对照试验的系统综述
Majid Kianmehr,Mohammad Reza Khazdair
Majid Kianmehr
Objective: High menstrual bleeding (HMB) is a common issue affecting women's health, often leading to significant physical and psychological distress. While several medical treatments are available, many women face treatm...
Dexamethasone-induced hepatic biochemical and pathological damages are attenuated by Cynodon dactylon extract containing hexadecanoic acid via reduction of glucose uptake: In vitro and in vivo studies [0.03%]
喜树碱诱导的肝生化和病理损伤通过减少葡萄糖摄入量由地菍提取物中含正己酸缓解:体内与体外研究
Sadaf Mottaghian,Ayshin Khalilarya,Hassan Malekinejad
Sadaf Mottaghian
Objective: The protective effects of ethanolic extract of Cynodon dactylon (CD) on dexamethasone (DEX)-induced hepatic injuries were investigated. Materia...
Nordihydroguaiaretic acid attenuates TNFα-dependent intercellular adhesion molecule-1 expression in cultured human umbilical vein endothelial cells via targeting TNFα-PI3K-NF-κB-ICAM1 pathway [0.03%]
Nordihydroguaiaretic酸通过作用于TNFα-PI3K-NF-κB-ICAM1途径而减弱TNFα依赖的人脐静脉内皮细胞间粘附分子表达
Tapan Kumar Mukherjee,Parth Malik,Raj Singh et al.
Tapan Kumar Mukherjee et al.
Objective: During inflammation and oxidative stress, vascular endothelial cell surfaces express high levels of adhesion molecules such as intercellular adhesion molecule 1 (ICAM1) which bind the circulatory leukocytes (e....
Vitex agnus-castus extract improved the endocrine profile and important gene expression in rat ovaries with polycystic ovary syndrome [0.03%]
Vitex agnus-castus提取物改善了多囊卵巢综合症大鼠卵巢内分泌状况和重要基因表达
Mahtab Abbaszadeh,Gholamali Jelodar,Aazam Salmani et al.
Mahtab Abbaszadeh et al.
Objective: The beneficial effect of Vitex agnus-castus on the female endocrine system has been reported. This study examines the impact of Vitex extract (VE) on the serum anti-Mullerian hormone (AMH), sex hormones, and P4...
Antioxidant efficacy of Cotoneaster nummularius in phenylhydrazine-induced hyperbilirubinemia: A rat model study [0.03%]
伏马茋对苯肼致高胆红素血症大鼠的抗氧化疗效研究
Faezeh Valipour,Akbar Safipour Afshar,Mohammad Azadbakht et al.
Faezeh Valipour et al.
Objective: This study investigated the hepatoprotective effects of Cotoneaster nummularius manna extract (CNE) against phenylhydrazine (PHZ)-induced hyperbilirubinemia and oxidative stress in a neonatal rat model. ...
A systematic review of the biological effects of resveratrol on venous thromboembolism [0.03%]
白藜醇的生物效应的系统性综述在静脉血栓形成中的作用
Hasan Momeni,Fatemeh Shirvani-Farsani,Iraj Baratpour et al.
Hasan Momeni et al.
Objective: Venous thromboembolism (VTE) has high morbidity in major surgery, serious injury, or during periods of inflammation and infection. VTE has serious complications, resulting in death. This review aims to evaluate...
Therapeutic potential of polyphenols in managing thalassemia: A comprehensive review [0.03%]
花青素在治疗地中海贫血中的潜力:全面回顾
Sajjad Jamali,Behzad Jamali,Marjan Golabi et al.
Sajjad Jamali et al.
Objective: This study aims to review the potential effects of polyphenols on iron overload and inflammation in patients with β-thalassemia. Materials and...