Lipid-based nanoparticles: advancing therapeutic strategies for vitiligo management [0.03%]
脂质基纳米颗粒：用于治疗白癜风的新策略
Mahdi Darvishi,Amir Mohammad Chekeni,Mohammad Fazelhosseini et al.
Mahdi Darvishi et al.
Vitiligo, a chronic autoimmune disorder characterized by the presence of depigmented skin patches, remains a therapeutic challenge due to its multifactorial pathogenesis and the absence of highly effective treatment options. Although the ex...
mtDNA copy number/ miR663/AATF axis in invasive ductal carcinoma of the breast [0.03%]
乳腺浸润性导管癌中线粒体DNA拷贝数/miR663/AATF轴
Farzaneh Dahi,Shirin Shahbazi,Loabat Geranpayeh
Farzaneh Dahi
Introduction: Mitochondrial DNA (mtDNA) copy number variations have been reported in multiple human cancers. Previous studies indicate that mitochondrial retrograde signaling regulates miR663, which plays a key role in tu...
Allogeneic Treg-derived artificial vesicles: A promising therapeutic modality for multiple sclerosis [0.03%]
同种异体Treg衍生的人工囊泡：治疗多发性硬化的潜在疗法
Irina Alekseevna Ganeeva,Elvina Maratovna Gilyazova,Arthur Ajdarovich Khannanov et al.
Irina Alekseevna Ganeeva et al.
Introduction: Multiple sclerosis (MS) is a chronic autoimmune disease of the central nervous system (CNS). CD4+ CD25+hi Tregs, which normally suppress immune responses, exhibit impaired function in MS. Treg-derived extrac...
Kimia Esmaeilzadeh,Sina Farzi Molan,Farshid Sefat et al.
Kimia Esmaeilzadeh et al.
Optimal skin healing is a sophisticated, coordinated process involving cellular and molecular interactions. Disruptions in this process can result in chronic wounds, necessitating medical intervention, particularly when the damage surpasses...
Photoplethysmography based non-invasive blood glucose estimation using systolic-diastolic framing MFCC features and machine learning regression [0.03%]
基于收缩-舒张MFCC特征和机器学习回归的PPG无创血糖估计方法研究
Ali Kermani,Hossein Esmaeili
Ali Kermani
Introduction: Accurate and non-invasive blood glucose estimation is essential for effective health monitoring. Traditional methods are invasive and inconvenient, often leading to poor patient compliance. This study introd...
Biomarkers for colorectal cancer detection: An insight into colorectal cancer and FDA-approved biomarkers [0.03%]
结直肠癌检测的生物标志物：结直肠癌及其FDA批准的生物标志物综述
Mohammad Yasin Zamanian,Darmadi Darmadi,Razieh Darabi et al.
Mohammad Yasin Zamanian et al.
Colorectal cancer (CRC) constitutes a significant global health challenge, accounting for a considerable proportion of cancer cases and associated mortality. Projections indicate a potential increase in new cases by 2040, attributed to demo...
MicroRNA-372-3p impairs fatty acid metabolism in hepatocellular carcinoma cells by targeting CPT1A and ACSL4 [0.03%]
microRNA-372-3p通过靶向CPT1A和ACSL4损害肝癌细胞的脂肪酸代谢
Chinnatam Phetkong,Thammachanok Boonto,Pannathon Thamjamrassri et al.
Chinnatam Phetkong et al.
Introduction: Hepatocellular carcinoma (HCC) remains a major cause of cancer mortality, and effective therapeutic options are limited. MicroRNA‑372‑3p (miR‑372‑3p) has been implicated in HCC, yet its exact role is unc...
Apoptotic and anti-metastatic effect of chrysin on CD44+ cancer stem cells from SW480 colorectal cancer cell line [0.03%]
染料木黄酮通过作用于SW480结肠癌细胞系的CD44+癌干细胞而产生的凋亡和抗转移效果
Yongyong Chen,Jing Zhao,Shaohua Wang et al.
Yongyong Chen et al.
Introduction: Cancer stem cells (CSCs) are very important for colorectal cancer (CRC) because they help the cancer start, spread, and metastasise. This makes them a key target for making better cancer treatments. This stu...
Hybrid deep learning models for text-based identification of gene-disease associations [0.03%]
基于文本的基因疾病关联识别的混合深度学习模型
Noor Fadhil Jumaa,Jafar Razmara,Sepideh Parvizpour et al.
Noor Fadhil Jumaa et al.
Introduction: Identifying gene-disease associations is crucial for advancing medical research and improving clinical outcomes. Nevertheless, the rapid expansion of biomedical literature poses significant obstacles to extr...
Enhanced efficacy of breast cancer treatment with etoposide-graphene oxide nanogels: A novel nanomedicine approach [0.03%]
依托泊苷-氧化石墨烯纳米凝胶增强乳腺癌治疗效果：一种新型纳米药物策略
Abbas Asoudeh-Fard,Milad Mohkam,Asghar Parsaei et al.
Abbas Asoudeh-Fard et al.
Introduction: Breast cancer represents a significant global health challenge, underscoring the need for innovative therapeutic strategies. This study explores the therapeutic potential of etoposide (ETO)-loaded graphene o...