CAR-T cell therapy as an approach for pediatric hematological malignancies in regenerative therapy: Current status and clinical outcomes [0.03%]
有关再生医学中儿童血液系统恶性肿瘤CAR-T细胞疗法的现状和临床结果的研究
Xiaoman Guo,Xueyin Jiang,Juan Zhang
Xiaoman Guo
Radiation therapy, chemotherapy, and surgery have been the standard cancer treatment approaches for many years. Even with these treatments, the majority of tumors still have a dismal prognosis. With complete remission rates ranging from 65%...
Role of non-coding RNA through nanomedicine: the novel therapeutic and diagnostic approaches [0.03%]
纳米药物介导的非编码RNA的作用：新颖的治疗和诊断方法
Kamyar Khoshnevisan,Mohammad J Eslamizade,Forough Shams
Kamyar Khoshnevisan
In today's rapidly advancing field of medical research, non-coding RNA (ncRNA) and nanomedicine have emerged as promising areas of study for therapeutic and diagnostic approaches. ncRNAs, previously considered "junk DNA" and hence insignifi...
Designing of multi-epitope vaccine against Varicella zoster virus (VZV) using immunoinformatics and structural analysis: In silico study [0.03%]
基于免疫信息学和结构分析的Varicella Zoster病毒多表位疫苗设计：一种离体研究方法
Mohamed J Saadh,Mareb Hamed Ahmed,Rafid Jihad Albadr et al.
Mohamed J Saadh et al.
Introduction: The Varicella-zoster virus (VZV) causes varicella (chickenpox) and herpes zoster (shingles), posing significant global health challenges. Despite existing vaccines, gaps in coverage and efficacy persist, nec...
Marine fungal metabolites as antiviral agents: Computer-aided drug screening for selective inhibition of African swine fever virus dUTPase [0.03%]
海洋真菌代谢产物作为抗病毒剂的作用：计算机辅助药物筛选非洲猪瘟病毒dUTP酶特异性抑制剂
Mark Andrian B Macalalad,Fredmoore L Orosco
Mark Andrian B Macalalad
Introduction: African swine fever (ASF) continues to be a significant threat to the global livestock industry due to its severe impact on pig populations. Currently, there are no approved therapeutic agents for the virus,...
Recent advancement in polymeric nanoparticles for oral chemotherapy: Transforming cancer treatment [0.03%]
口服化疗用聚meric纳米粒子的最新进展：变革癌症治疗
Karthik Mangu,Ruhan Gudeli,Md Rizwanullah
Karthik Mangu
Oral chemotherapy offers an attractive alternative to conventional intravenous administration by providing high patient compliance and improved treatment adherence. However, several challenges, like poor drug solubility, enzymatic degradati...
Recent innovations in nanomedicine and nano-based techniques for the treatment of breast cancer [0.03%]
乳腺癌治疗的纳米医学及纳米技术近期创新成果
Meena Bhandari,Seema Raj,Md Sabir Alam
Meena Bhandari
Breast cancer (BC) is a persistent global health challenge, necessitating innovative therapeutic strategies. Recently, nanotechnology has appeared as a transformative methodology to treat BC, suggesting precise targeting, controlled drug de...
Revolutionizing cancer therapy: Monoclonal antibodies in radiosensitization [0.03%]
革命性癌症疗法：单克隆抗体在放射增敏中的应用
Abolfazl Bemidinezhad,Yasaman Abolhassani,Mojgan Noroozi-Karimabad et al.
Abolfazl Bemidinezhad et al.
Cancer treatment has advanced significantly, yet traditional modalities such as radiotherapy still encounter challenges, including damage to healthy tissues and limited tumor specificity. Monoclonal antibodies (mAbs) have emerged as powerfu...
Investigate the co-culture effects of BM-mesenchymal stem cells on the promotion of apoptotic pathways of CD34+leukemic stem cells [0.03%]
骨髓间充质干细胞共培养对CD34⁺白血病干细胞促凋亡效应的研究
Mei Ding,Chuanhua Jia
Mei Ding
Introduction: The potential clinical application of mesenchymal stem cells (MSCs) in cell-based treatment makes them particularly interesting. The use of MSC-engaged therapies in cancer treatment is becoming more and more...
Development, in vitro, and in vivo assessments of PCL-gelatin-βTCP fibrous scaffolds for cardiac regeneration [0.03%]
用于心脏再生的PCL-明胶-βTCP纤维支架的开发及体外和体内评价
Mahnaz Fathi,Nafiseh Baheiraei,Nahid Moradi et al.
Mahnaz Fathi et al.
Introduction: Cardiovascular disease is a leading cause of death worldwide. Tissue engineering offers a promising solution for promoting tissue regeneration at the infarcted site. In this study, beta-tricalcium phosphate ...
microRNAs shuttled by mesenchymal stromal cell-derived exosomes in coronary artery disease: A systematic review of preclinical studies [0.03%]
冠心病中间质基质细胞衍生的外泌体传递的微小RNA：系统性回顾预临床研究
Soroush Mostafavi,Amin Arasteh,Seyedeh Mina Mostafavi Montazeri et al.
Soroush Mostafavi et al.
Introduction: Coronary artery disease (CAD) is a life-threatening cardiac condition with high morbidity and mortality worldwide. This systematic review article highlighted the therapeutic roles of mesenchymal stromal cell...