Establishing a sustainable quality management system in a public clinical laboratory: The case of Mbagathi Hospital Laboratory in Kenya [0.03%]
建立可持续的质量管理体系：以肯尼亚M包加蒂医院实验室为例
Jully A Okonji,Martin K Maitima,Peter K Kariuki et al.
Jully A Okonji et al.
Background: Between 2021 and 2023, the Association of Public Health Laboratories, in collaboration with the US Centers for Disease Control and Prevention in Kenya, initiated a laboratory improvement programme at the Mbaga...
Burden of rare genetic variants in genes associated with cancer among Malawian cervical cancer patients [0.03%]
马拉维宫颈癌患者中与癌症相关的基因罕见遗传变异的负担
Samuel D Gwayi,Tamiwe Tomoka,Emile R Chimusa et al.
Samuel D Gwayi et al.
Background: Cervical cancer (CC) is one of the most common cancer types affecting women globally. Cervical cancer is largely associated with human papillomavirus infections; however, approximately 5% to 11% of CC cases ar...
The road map for ISO 15189-laboratory accreditation: The Experience of Manhiça Health Research Centre (CISM) laboratory, in southern Mozambique [0.03%]
ISO 15189医学实验室认证路线图：莫桑比克曼希卡健康研究中心(CISM)的实践体会
Delfino C Vubil,Anelsio Cossa,Ergel Salvador et al.
Delfino C Vubil et al.
Background: Accreditation is an effective way to recognise the quality and competence of a clinical laboratory. Here we describe the steps towards ISO 15189:2012 accreditation of the Manhiça Health Research Centre labora...
Friedewald and Martin-Hopkins formulae for estimating low-density lipoprotein cholesterol in a Malagasy population [0.03%]
马达加斯加人群胆固醇估计公式的一项研究
Faralahy H Rakotonjafiniarivo,Tokinomenjanahary Antsonantenaina,Mahefa S Rakotomalala et al.
Faralahy H Rakotonjafiniarivo et al.
Background: Low-density lipoprotein cholesterol (LDL-C) estimation is commonly used in Madagascar due to cost-effectiveness. However, genetic variability and formula limitations may affect accuracy. ...
Whole-genome sequencing for surveillance of Salmonella at a public health institution in South Africa [0.03%]
南非公共卫生机构的沙门氏菌全基因组测序监测研究
Anthony M Smith,Phuti Sekwadi,Hlengiwe M Ngomane et al.
Anthony M Smith et al.
Background: Whole-genome sequencing (WGS) is transforming communicable disease surveillance globally. The National Institute for Communicable Diseases, South Africa, participates in national laboratory-based surveillance ...
Age- and gender-based frequency and association of common myeloproliferative mutations in a South African cohort [0.03%]
基于年龄和性别的人群常见髓系增生性突变的频率及关联性研究
Bathabile Mbele,Kapila Bhowan,Brendon Roets
Bathabile Mbele
Background: Age, gender, and mutation type are key risk factors for myeloproliferative neoplasms (MPNs). Africa remains under-represented in global cancer statistics due to limited population-based genomic data. ...
The β-goblin gene architecture in individuals with and without sickle cell disease in Nigeria: Implications for β-thalassaemia trait diagnosis [0.03%]
尼日利亚镰状细胞病患者和非患者的β-球蛋白基因簇结构及对轻型地中海贫血诊断的启示
Oluwatoyin A Babalola,Biobele J Brown,Foluke Fasola et al.
Oluwatoyin A Babalola et al.
Background: β-thalassaemia is considered rare in Africa; however, recent screening-based studies suggest a β-thalassaemia trait prevalence of 6% - 10% among individuals with sickle cell disease (SCD) and up to 25% in th...
Effects of disease-modifying drugs on serum neurofilament light chain, chitinase-3-like-1 protein levels, and selected plasmacytoid dendritic cell biomarkers in relapsing-remitting multiple sclerosis [0.03%]
用于治疗复发缓解型多发性硬化的疾病修正药物对血清神经丝轻链、几丁质酶3样蛋白1水平及选定的浆细胞样树突状细胞生物标志物的影响
Dalia T Kamal,Sohair K Sayed,Tarek A Rageh et al.
Dalia T Kamal et al.
Background: Multiple sclerosis (MS) is a neurodegenerative central nervous system disorder causing axonal damage and disability. Relapses develop over hours or days and then subside over weeks. Disease-modifying drugs (DM...
Audit of pre-transfusion testing practices in hospital blood banks across Tanzania: A national survey [0.03%]
坦桑尼亚医院输血前检验实践的审计调查——一项全国性调查研究
Oscar F Mwashiuya,Magdalena A Lyimo,Deus J Mogela et al.
Oscar F Mwashiuya et al.
Background: Blood transfusion is a lifesaving procedure performed across all healthcare levels in Tanzania. Despite significant investment in blood collection and screening, hospital transfusion practices have received le...
In vitro antibacterial activity of tigecycline against multidrug-resistant bacteria isolated at the Sourô Sanou University teaching hospital in Bobo-Dioulasso, Burkina Faso [0.03%]
体外替加环素对 Burkina Faso 博博迪乌拉苏大学教学医院分离的多药耐药菌的抗菌活性研究
Odilon D Kaboré,Mélissa J Gonfouli,Merci Muhigwa et al.
Odilon D Kaboré et al.
Background: Tigecycline, an antibiotic effective against multidrug-resistant bacteria (MDRB), remains inaccessible in Burkina Faso's hospitals for urgent care. Given the resulting therapeutic challenges and mortality in e...