Establishment of haemoglobin A2 reference intervals in Pretoria, South Africa: A retrospective secondary data analysis [0.03%]
南非比勒陀利亚血红蛋白A2参考区间的建立：一项基于回顾性二次数据分析的研究
Cailin Nieuwenhuizen,Tshiphiri Netshidzivhani,Johan Potgieter
Cailin Nieuwenhuizen
Background: Haemoglobinopathies are one of the most common inherited diseases worldwide. Quantification of haemoglobin A2 is necessary for the diagnosis of the beta thalassaemia trait. In this context, it is important to ...
Effect of sputum quality and role of Xpert® MTB/ RIF assay for detection of smear-negative pulmonary tuberculosis in same-day diagnosis strategy in Addis Ababa, Ethiopia [0.03%]
评价痰液质量及Xpert®MTB/RIF检测在平诊策略中对埃塞俄比亚亚的斯亚贝巴肺涂阴结核患者诊断价值的效果研究
Waganeh Sinshaw,Abebaw Kebede,Adane Bitew et al.
Waganeh Sinshaw et al.
Background: There is limited information on the performance of the Xpert® MTB/RIF test for diagnosis of smear-negative pulmonary tuberculosis (SNPT) and rifampicin resistance (RR) in the same-day diagnosis approach. The ...
Tuberculosis-loop-mediated isothermal amplification implementation in Cameroon: Challenges, lessons learned and recommendations [0.03%]
喀麦隆结核病环介导等温扩增实施中的挑战、经验及建议
Valerie F Donkeng-Donfack,Suzanne M Ongoulal,Yvonne J Djieugoue et al.
Valerie F Donkeng-Donfack et al.
Background: Until 2016, microscopy was the main tool for the early detection of pulmonary tuberculosis in Cameroon, especially in remote settings. Due to the poor sensitivity of microscopy, there was a need to implement a...
Occurrence and antimicrobial susceptibility patterns of Salmonella species from poultry farms in Ibadan, Nigeria [0.03%]
尼日利亚伊巴丹家禽养殖场沙门氏菌的分离和耐药性分析
Terese G Orum,Olayinka O Ishola,Oluwawemimo O Adebowale
Terese G Orum
Background: Salmonella species are among the major foodborne pathogens causing diseases of economic and public health implications in poultry and humans globally. ...
Prevalence of hepatitis B virus core antibodies among blood donors in Nigeria: Implications for blood safety [0.03%]
尼日利亚献血者乙肝病毒核心抗体的流行率：对血液安全性的含义
Foluke A Fasola,Adeola A Fowotade,Adedayo O Faneye et al.
Foluke A Fasola et al.
Background: Anti-hepatitis B core antibody (anti-HBc) testing improves transfusion safety by detecting past and current hepatitis B virus (HBV) infection while detecting hepatitis B surface antigen (HBsAg) in serology-neg...
Implementing an intensified mentorship approach towards accelerated medical laboratory accreditation in 10 counties in Kenya [0.03%]
在肯尼亚10个郡实施强化指导方法以加快医学实验室认证的速度
Susan K Musau,Christina Mwachari,Elvis Kirui et al.
Susan K Musau et al.
Background: Despite Kenya's roll-out of the Strengthening Laboratory Management Towards Accreditation programme in 2010, most laboratories had not made significant or tangible improvements towards accreditation by 2016. I...
Challenges with the pursuit of ISO 15189 accreditation in a public health laboratory in Ghana [0.03%]
加纳公共卫生实验室ISO 15189认证过程中的挑战
Seth Attoh,Francis K M Tetteh,Mary McAddy et al.
Seth Attoh et al.
Background: Accreditation is important for all medical laboratories, particularly public health laboratories in developing countries. Several laboratories in Ghana implemented the requirements of the International Organiz...
COVID-19 mass testing and sequencing: Experiences from a laboratory in Western Kenya [0.03%]
肯尼亚西部实验室的 COVID-19 大规模筛查和基因测序经验
John N Waitumbi,Esther Omuseni,Josphat Nyataya et al.
John N Waitumbi et al.
Background: The Basic Science Laboratory (BSL) of the Kenya Medical Research Institute/Walter Reed Project in Kisumu, Kenya addressed mass testing challenges posed by the emergent coronavirus disease 2019 (COVID-19) in an...
Therapeutic drug monitoring of phenytoin and valproic acid in critically ill patients at Windhoek Central Hospital, Namibia [0.03%]
纳米比亚温得霍克中央医院危重病人的苯妥英和丙戊酸治疗药物监测研究
Bonifasius S Singu,Helen Morrison,Lydia Irengeya et al.
Bonifasius S Singu et al.
Background: Phenytoin and valproic acid, anticonvulsants, have a low therapeutic index and are highly plasma protein bound, mainly to albumin. Hypoalbuminaemia is common in critically ill patients and increases the unboun...
Formulation of phage cocktails and evaluation of their interaction with antibiotics in inhibiting carbapenemase-producing Klebsiella pneumoniae in vitro in Kenya [0.03%]
肯尼亚肺炎克雷伯菌碳青霉烯耐药株噬菌体鸡尾酒的配制及其与抗生素联合应用效果的体外评价
Noutin F Michodigni,Atunga Nyachieo,Juliah K Akhwale et al.
Noutin F Michodigni et al.
Background: The development of alternative control measures, such as phage therapy or adjunctive therapy, is urgently needed to manage the dissemination of carbapenemase-producing Klebsiella pneumoniae. ...