Establishment and preliminary validation of a noninvasive diagnostic model for food allergy in infants [0.03%]
婴儿食物过敏非侵入性诊断模型的构建和初步验证
Yajuan Gao,Hua Zhang,Nini Dai et al.
Yajuan Gao et al.
Background: Infants are at a high risk of food allergy (FA); however, owing to the lack of commonly recognized simple and noninvasive diagnostic tools, definitive diagnosis of infantile FA is challenging. In this study, w...
Development and evaluation of a predictive model for central precocious puberty in girls [0.03%]
儿童中枢性早熟的预测模型构建及验证研究
Yufan Wu,Chaoliang Xu,Jingdi Li et al.
Yufan Wu et al.
Background: Early puberty, particularly central precocious puberty (CPP), is an increasingly common pediatric endocrine disorder affecting young girls. Existing CPP predictive models either rely on post-gonadotropin-relea...
Xiaolei Zeng,Liyuan Hu
Xiaolei Zeng
Background and objective: Infantile hypophosphatemia (defined as a serum phosphate level below 1.6 millimoles per liter before 6 months of age and below 1.48 millimoles per liter between 6 months and 1 year of age) is one...
Ahmad Anouti,Amal Aqul,Johanna Ascher Bartlett et al.
Ahmad Anouti et al.
Fontan-associated liver disease (FALD) is a universal consequence of the Fontan circulation and a growing cause of morbidity. Clinical outcome stratification is difficult because conventional tests lack sensitivity. In this review, we aim t...
Diagnostic yield of exome and genome sequencing for critically ill pediatric cardiac patients [0.03%]
外显子组和基因组测序在重症先天性心脏病患儿中的诊断价值评估
Angela C Onorato,Rachel Gosselin,Bimal P Chaudhari et al.
Angela C Onorato et al.
Background: Genetic testing guidelines for children in cardiac intensive care units (CICUs) remain limited despite a high prevalence of genetic diseases among this population. Advances in next-generation sequencing techno...
Blood-based inflammatory parameters and machine learning models for mortality prediction in critically ill pediatric pneumonia: a retrospective cohort study [0.03%]
基于血液的炎症参数和机器学习模型在危重儿童肺炎患者死亡率预测中的应用：回顾性队列研究
Shuai Hu,Wanmin Xia,Pei Tao et al.
Shuai Hu et al.
Background: Pneumonia remains a leading cause of morbidity and mortality in critically ill children, yet comprehensive prognostic biomarkers specifically validated in pediatric intensive care settings remain limited. Iden...
Combined itraconazole and terbinafine therapy for pediatric kerion: a report of two cases [0.03%]
两例儿童kerion的联合伊曲康唑和特比萘芬治疗报告
Di Ma,Yuanyuan Lu,Feng Fang et al.
Di Ma et al.
Background: With improvements in socioeconomic conditions and public health, kerion-type tinea capitis has become much less common in China. As a result, many pediatricians have limited exposure to this condition, leading...
TFAP2D drives neuroblastoma progression: a disulfidptosis-fatty acid metabolism-based molecular subtyping and prognostic model [0.03%]
TFAP2D驱动神经母细胞瘤进展：基于二硫键凋亡-脂肪酸代谢的分子分型和预后模型
Xiaoying Li,Baocheng Gong,Tongyuan Qu et al.
Xiaoying Li et al.
Background: Neuroblastoma (NB) is recognized as the predominant extracranial malignant solid tumor in children and adolescent; the prognosis for high-risk patients remains poor. This limitation stems from its low mutation...
Jian Li,Mengwen Yan,Tianjiao Hu et al.
Jian Li et al.
Background: Congenital mesoblastic nephroma (CMN) is a rare renal tumor predominantly occurring in neonates and young infants, and standardized treatment guidelines remain lacking. This study aimed to summarize the clinic...
Prevalence and molecular characteristics of respiratory syncytial virus in hospitalized children in Shenzhen during the COVID-19 pandemic: a retrospective study [0.03%]
新冠肺炎疫情期间深圳市住院患儿呼吸道合胞病毒流行及分子特征的回顾性研究
Cuiling Lu,Jieming Yu,Chunyuan Wu et al.
Cuiling Lu et al.
Background: The prevalence of respiratory syncytial virus (RSV) caused acute lower respiratory tract infections (ALRTI) among children, which have made children susceptible to severe infection. This study aims to determin...