Apolipoprotein M delays the development of atherosclerosis by regulating autophagy and mitochondrial function [0.03%]
载脂蛋白M通过调节自噬和线粒体功能延缓动脉粥样硬化的发展
Yuanping Shi,Shuang Yao,Binhua Jiang et al.
Yuanping Shi et al.
Background: Apolipoprotein M (ApoM), a protein component of lipoproteins, is closely related to the development of atherosclerosis, but the specific mechanism remains elusive. Mitochondrial DNA damage can contribute to at...
Assessment of left ventricular systolic function using pressure-strain loops in offspring of women with gestational diabetes mellitus: a prospective cohort study [0.03%]
妊娠糖尿病女性后代左心室收缩功能压力-应变环分析:前瞻性队列研究
Xu-Feng Cao,Li-Li Su,Ying-Chao Fan et al.
Xu-Feng Cao et al.
Background: Gestational diabetes mellitus (GDM) increases the risk of cardiovascular abnormalities in offspring. The objective of this study is to assess changes in left ventricular myocardial work using the left ventricu...
"Real world" medical care of patients with Fabry disease by primary care physicians, internists or general practitioners [0.03%]
初级保健医师、内科或全科医师对法布雷病患者的“现实世界”医疗护理
Oliver Mayer,Harald Kaemmerer,Peter Ewert et al.
Oliver Mayer et al.
Background: Fabry disease (FD) is a rare hereditary X-linked disorder of glycosphingolipid metabolism caused by a deficiency of α-galactosidase A leading to the accumulation of glycosphingolipids in lysosomes. Clinical m...
Xinyue Zhang,Yuanyuan Du,Jiaonan Xu et al.
Xinyue Zhang et al.
Background: Recent studies have proved that long non-coding RNAs (lncRNAs) are closely related to the pathogenesis of cardiovascular diseases (CVDs), but their exact regulatory mechanism including non-coding as well as co...
Diagnosis, management, and outcome of heart failure in congenitally corrected transposition of the great arteries (ccTGA)-a narrative review [0.03%]
大动脉调转术(ccTGA)心力衰竭的诊断、管理和预后——叙述性综述
Motoki Komori,Maria Luisa Benesch Vidal,Kenta Imai et al.
Motoki Komori et al.
Background and objective: Congenitally corrected transposition of the great arteries (ccTGA) remains a rare congenital disorder with a wide range of manifestations. The management of heart failure (HF) of the systemic rig...
Beta-blockers in post-myocardial infarction with preserved ejection fraction: systematic review and meta-analysis [0.03%]
射血分数保留的心肌梗死后β受体阻滞剂治疗的系统评价和meta分析
Rafael Alessandro Ferreira Gomes,Ludmila Cristina Camilo Furtado,Marcela Vasconcelos Montenegro et al.
Rafael Alessandro Ferreira Gomes et al.
Background: Myocardial infarction (MI) remains one of the main causes of mortality worldwide. Beta-blockers (BBs) are an essential component in the pharmacological treatment for MI. The long-term role of BB in patients wi...
Effectiveness of intravenous administration of a combination of sufentanil and esketamine on post-cardiac surgery pain management and depression: a randomized controlled trial [0.03%]
硫酸舒芬太尼与艾司氯胺酮静脉联合用药对心脏手术后镇痛及抑郁的疗效研究:随机对照试验
Sen Xu,Tianyu Liang,Weicai Xu
Sen Xu
Background: Cardiac surgery often results in significant postoperative pain, which can lead to complications and prolonged recovery. Pain and depression are closely linked, with effective pain management potentially reduc...
Development of peripheral biomarker-based prognostic nomograms for short-term and long-term survival in immune checkpoint inhibitor-associated myocarditis [0.03%]
基于外周生物标志物的预后预测模型在免疫检查点抑制剂相关心肌炎短期和长期生存期中的应用发展
Zhengkun Guan,Tiezhu Yao,Guang Liu et al.
Zhengkun Guan et al.
Background: Immune checkpoint inhibitor-associated myocarditis (ICI myocarditis) is a rare but highly fatal immune-related adverse reaction. This study aimed to develop nomogram prognostic models for both short-term and l...
Aneurysm of the fetal right ventricular free wall progressing to hypoplastic right heart syndrome: prenatal diagnosis, maternal digoxin therapy, and successful surgical intervention-a case report [0.03%]
胎儿右心室游离壁动脉瘤发展成右心发育不全综合征:产前诊断、母体地高辛治疗及成功手术干预的病例报告
Krzysztof Serafin,Agnieszka A Nocun,Jacek Kolcz et al.
Krzysztof Serafin et al.
Background: Congenital right ventricular aneurysm (CVA) and diverticulum (CVD) are rare heart diseases that can be diagnosed prenatally. Data on the natural progression of ventricular aneurysms or diverticula identified d...
Investigating the causal relationship between genetically determined metabolites and ischemic stroke functional outcomes: a Mendelian randomization study [0.03%]
遗传性代谢产物与缺血性卒中预后的因果关系调查:孟德尔随机化研究
Xiaobei Zhang,Gehong Liang,Ying Zheng et al.
Xiaobei Zhang et al.
Background: Ischemic stroke functional outcomes are critical determinants of recovery quality; however, our understanding of the underlying metabolic influences remains incomplete. Mendelian randomization (MR) is ideal fo...