Targeting low-risk triple-negative breast cancer: a review on de-escalation strategies for a new era [0.03%]
低风险三阴性乳腺癌的治疗靶向：对新纪元中减毒策略的评论
Filomena Marino Carvalho
Filomena Marino Carvalho
Triple-negative breast cancer (TNBC) is a subtype of breast cancer lacking estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor 2 (HER2) expression. Comprising 15-20% of breast cancers, TNBC is typi...
Advances in antibody-drug conjugates in the treatment of advanced triple-negative breast cancer: a narrative review [0.03%]
抗体药物偶联物在治疗晚期三阴性乳腺癌中的进展：一项叙述性回顾
Kuikui Jiang,Shusen Wang
Kuikui Jiang
Background and objective: Triple-negative breast cancer (TNBC) is more aggressive when compared with other breast cancer subtypes, and advanced TNBC (aTNBC) has always been a challenge for clinical treatment. In recent ye...
Recent advances and updated highlights in breast cancer pathologic diagnosis: a narrative review [0.03%]
乳腺癌病理诊断的近期进展和最新亮点 ： 故事性回顾
Yueping Liu
Yueping Liu
Background and objective: With the rapid development of breast cancer treatment, breast cancer pathologic diagnosis has faced many requirements and challenges. This article reviews and summarizes important results that wi...
Pathological precision diagnosis and recent advances in HER2 low and ultralow in breast cancer: a narrative review [0.03%]
乳腺癌HER2低表达及超低表达的精准诊断和研究进展：综述文章
Jiuyan Shang,Yueping Liu
Jiuyan Shang
Background and objective: The novel antibody-drug conjugate (ADC) analogues are emerging in the field of human epidermal growth factor receptor 2 (HER2) low and ultralow breast cancer, and accurate screening of patients w...
Regulation of PI3K signaling in cancer metabolism and PI3K-targeting therapy [0.03%]
PI3K信号在癌症代谢和PI3K靶向治疗中的调节作用
Beinan Han,Xiaorong Lin,Hai Hu
Beinan Han
The phosphatidylinositol-3-kinase (PI3K) signaling plays a key role in various cellular functions and is frequently activated in cancer, making it an attractive therapeutic target. The PI3K signaling pathway influencing glucose metabolism, ...
Xin-Yi Liu,Tian-Jian Yu,Zhi-Ming Shao
Xin-Yi Liu
Understanding the relationship between breast cancer, immune checkpoint inhibitors, and gut microbiota: a narrative review [0.03%]
乳腺癌、免疫检查点抑制剂和肠道微生物群之间的关系：综述
Gabriella Hrubesz,Jennifer Leigh,Terry L Ng
Gabriella Hrubesz
Background and objective: The composition of gut microbiota plays an important role in predicting and influencing outcomes of cancer treated with immunotherapy. Our objective is to summarize the role of gut microbiota and...
Adjuvant CDK4/6 inhibitors in hormone receptor-positive early breast cancer: one fits all? [0.03%]
激素受体阳性早期乳腺癌辅助治疗的CDK4/6抑制剂：适合所有人吗？
Caterina Gianni,Eleonora Nicolò,Massimo Cristofanilli
Caterina Gianni
Strategies for the treatment of hormone receptor-positive HER2-low breast cancer based on clinical practice: a round table discussion [0.03%]
激素受体阳性低HER2乳腺癌的治疗策略——临床实践圆桌讨论
Xiang Huang,Yijia Hua,Chunxiao Sun et al.
Xiang Huang et al.
Human epidermal growth factor receptor 2 (HER2)-low breast cancer is a newly identified targetable subset of breast tumors, and its clinical characteristics and treatment strategies are controversial. The emergence of novel anti-HER2 antibo...
Breast ultrasound knobology and the knobology of twinkling for marker detection [0.03%]
乳腺超声影像特征及用于检测标记物的闪烁征影像特征
Christine U Lee,Gina K Hesley,Taylor A Pierson et al.
Christine U Lee et al.
Breast ultrasound utilizes various scanning techniques to acquire optimal images for diagnostic evaluation. During interventional procedures, such as ultrasound-guided biopsies or preoperative localizations, knowledgeable and purposeful sca...