Neoadjuvant immunotherapy in resectable hepatocellular carcinoma: A meta-analysis of the current evidence [0.03%]
可切除肝细胞癌新辅助免疫治疗的meta分析：现有证据的综述
Ottavia Cicerone,Barbara Oliviero,Stefania Mantovani et al.
Ottavia Cicerone et al.
Background: Hepatocellular carcinoma (HCC) remains a leading cause of cancer-related mortality worldwide. Despite improvements in surgical techniques and systemic therapies, long-term outcomes after liver resection are li...
Catalase: The golden key to regulate oxidative stress in breast cancer [0.03%]
过氧化氢酶：调节乳腺癌氧化应激的“金钥匙”
Jia-Wei Liu,Wen-Jia Chen,Yang-Zheng Lan et al.
Jia-Wei Liu et al.
Catalase (CAT) is a kind of tetrameric protein in the human body, play as a key regulator for controlling oxidative stress. The main function of CAT is to regulate the concentration of hydrogen peroxide (H2O2) by catalyzing the decompositio...
Abnormal expression and potential clinical value of oncogenic Krüppel-like factor-5 in lung squamous cell carcinoma [0.03%]
肿瘤基因Kruppel样因子5在肺鳞癌异常表达及潜在临床意义
Yang Shi,Wen-Li Sai,Jin-Liang Chen et al.
Yang Shi et al.
Background: Krüppel-like factor-5 (KLF5) is a zinc-finger transcription factor related to tumor progression. However, the relationship between KLF5 and lung cancer remains to be identified. ...
Circulating tumor DNA in biliary tract cancers: A review of current applications [0.03%]
循环肿瘤DNA在胆道癌中的应用现状及展望：综述
Maria Fernanda Teixeira,Mitesh Borad,Pedro Luiz Serrano Uson Junior
Maria Fernanda Teixeira
Molecular profiling of biliary tract cancers (BTCs) has paved the way for a broader range of therapeutic options, leading to improved survival outcomes. Given the challenges of tissue evaluation in BTCs, circulating tumor DNA (ctDNA) has em...
Zhuo-Yu Li,Yuan Yang,Rui Wang et al.
Zhuo-Yu Li et al.
Significant progress has been made in cancer control in China over the past decades, but one of the crucial issues remains the low proportions of early-stage diseases among the leading cancers. Subnational cancer control in China has divers...
Neuro-tumor interactions: Multi-dimensional mechanisms of neurotransmitter regulation in tumor immune evasion and metabolic reprogramming [0.03%]
神经肿瘤相互作用：多维度神经递质调控机制在肿瘤免疫逃逸和代谢重编程中的作用
Ze-Kai Li,Jia-Lin Liao,Min-Rui Luo et al.
Ze-Kai Li et al.
Neurotransmitter-mediated regulation plays a multi-dimensional role in the tumor microenvironment, profoundly influencing key processes such as tumor immune evasion, metabolic reprogramming, and metastasis. However, the upstream regulatory ...
From infection to invasion: The role of deleted in malignant brain tumors 1 in Helicobacter pylori-driven gastric cancer [0.03%]
从感染到入侵：Deleted in Malignant Brain Tumors 1在Helicobacter pylori驱动的胃癌中的作用
Ionut Negoi
Ionut Negoi
Gastric cancer (GC) remains a major health challenge worldwide, with Helicobacter pylori (H. pylori) infection playing a key role in its development. H. pylori creates a mutagenic environment in the stomach by causing chronic inflammation, ...
Gut microbiome and nutritional strategies in gastrointestinal cancers: Clinical implications and therapeutic perspectives [0.03%]
肠道微生物组和营养策略在消化系统癌症中的临床意义和治疗前景
Vilma Pacheco-Barcia,Axel Mariño-Mendez,Enrique Hernandez-Jimenez et al.
Vilma Pacheco-Barcia et al.
Gastrointestinal malignancies, particularly pancreatobiliary and gastroesophageal cancers, are associated with poor prognosis due to their frequent late-stage diagnosis. Many of these tumors contribute to anorexia-cachexia syndrome and maln...
Overcoming chemoresistance in non-small cell lung cancer: Insights into the influence of inflammatory factors on treatment response [0.03%]
克服非小细胞肺癌化疗耐药性：炎症因子对治疗反应影响的见解
Yue Dai,Ya-Yun Liu,Nian Cao et al.
Yue Dai et al.
Background: Non-small cell lung cancer (NSCLC) is frequently characterized by poor response to cisplatin (DDP)-based chemotherapy, with increasing evidence suggesting that inflammatory cytokines in the tumor microenvironm...
Sidedness matters: Colon cancer outcomes in low-resource settings [0.03%]
以部位分型对结肠癌患者进行分类可改善医疗资源有限情况下的治疗效果
Jaime González-Montero,Guillermo Valenzuela,Carlos I Rojas et al.
Jaime González-Montero et al.
Colon cancer (CC) laterality (right vs left) is recognized as a key determinant of clinical outcomes and treatment decisions in metastatic CC. Right-sided CC (RCC) often presents in older individuals and is associated with higher rates of K...