Ibrahim O Sawaied,Abraham O Samson,Efrat Golan
Ibrahim O Sawaied
Background: Long-term proton pump inhibitor (PPI) therapy is widely prescribed for acid-related disorders. Emerging evidence associates prolonged use with potential adverse outcomes, including gastric cancer. Despite incr...
Ferritin as a novel predictive index for nasopharyngeal carcinoma survival and therapeutic efficacy of different chemotherapy regimens [0.03%]
铁蛋白可作为鼻咽癌生存预测及不同化疗方案疗效评估的新指标
Qi Tang,Yao Wu,Lin Chen et al.
Qi Tang et al.
Background: In the treatment of nasopharyngeal carcinoma (NPC), there is a lack of effective assessment of the long-term effects on patients. Searching for an effective evaluation scheme and screening a reliable index for...
Beyond sensitivity and specificity: Redefining the era connotation of "low-risk" in pancreatic cancer screening [0.03%]
超越灵敏度和特异度：重新定义胰腺癌筛查中“低风险”的时代内涵
Rui-Gang Wang
Rui-Gang Wang
Pancreatic cancer remains a highly lethal malignancy, primarily due to late-stage diagnosis. Current screening paradigms, which focus exclusively on high-risk individuals, leave the vast "low-risk" population unscreened. This conventional b...
Kita-Kyushu lung cancer antigen-1 expression in initial gastric tumors predicts multiple cancer development: A pilot study [0.03%]
基塔九州肺癌抗原1在初始胃肿瘤中的表达预测多发癌的发生：一项初步研究
Nobue Futawatari,Takashi Fukuyama,Yusuke Akimoto et al.
Nobue Futawatari et al.
Background: We have previously reported that the cancer/testis antigen Kita-Kyushu lung cancer antigen-1 (KK-LC-1) is frequently expressed in gastric cancer (GC), with a particularly high positivity rate observed in patie...
Single-cell differential abundance detection: A new angle on dissecting tumor heterogeneity [0.03%]
单细胞差异丰度检测：解析肿瘤异质性的新视角
Ying-Xue Xiao,Jing Sun,Ling-Ling Xie et al.
Ying-Xue Xiao et al.
Tumor heterogeneity is one of the central challenges in oncology, contributing to treatment resistance and disease recurrence. Bulk RNA sequencing has advanced understanding of tumor biology, yet its averaging effect conceals cell type-spec...
Pleiotropic regulation of mitochondrial translational factors in governing proliferation, apoptosis and metastasis during cancer progression [0.03%]
癌细胞增殖、凋亡和转移过程中线粒体蛋白合成调控因素的多效性作用机制研究
Nikita Agarwal,Uttam Sharma,Akshi Shree et al.
Nikita Agarwal et al.
Mitochondrial translation relies on the coordinated activity of mitoribosomes, mitochondrial ribosome proteins, mitochondria-specific transfer RNAs, and dedicated translation factors, including mitochondrial initiation factor 2/3, mitochond...
Post-treatment triglyceride-glucose index as survival protective factors in patients with esophageal squamous cell carcinoma [0.03%]
术后甘油三酯-葡萄糖指数作为食管鳞癌患者的生存保护因素
Ling Xiao,Yu-Di Liu,Xue Zhang et al.
Ling Xiao et al.
Background: Patients with esophageal cancer exhibit marked variability in prognosis, highlighting the need for metabolism-related biomarkers. Although metabolic reprogramming is considered to be correlated with the progno...
Yu Wang,Zhe Wang,Yue-Cui Tang et al.
Yu Wang et al.
Background: Adult sacrococcygeal teratoma (SCT) is extremely rare in clinical practice, with most cases manifesting as mature cystic types. Given the scarcity of clinical studies and literature on this topic, standardized...
Prognostic significance of PD-L1/PD-1 co-expression and CXCR3-driven inflammatory signatures in Egyptian patients with lymphoproliferative neoplasms [0.03%]
PD-L1/PD-1共表达和CXCR3驱动的炎性特征在埃及淋巴增生性疾病患者中的预后意义
Dalia E Sherief,Nahla Nosair,Aya Mohammed Abdelhameed et al.
Dalia E Sherief et al.
Background: Lymphoproliferative neoplasms (LPNs) such as chronic lymphocytic leukemia and non-Hodgkin lymphomas are clinically heterogeneous and frequently associated with recurrence and poor outcomes. Immune checkpoint m...
Myeloid sarcoma transformed from myeloproliferative neoplasm: A case report and review of literature [0.03%]
由骨髓增殖性肿瘤转化而来的粒细胞肉瘤一例报道及文献复习
Shu-Han Zhong,Jie Lou,Ai-Qi Zhao et al.
Shu-Han Zhong et al.
Background: Myeloid sarcoma (MS) is a rare hematological malignancy that may be associated with myelodysplastic or myeloproliferative neoplasms. Herein, we report a case of transformation from myelofibrosis to MS. ...