Kathleen M McTigue,Stephanie D Stepp,Charity G Moore et al.
Kathleen M McTigue et al.
Objective: To understand the incidence and persistence of severe obesity (≥1.2× 95th BMI percentile-for-age) in girls across the transition to adolescence, and map developmental trajectories of adolescent severe obesity...
The Burden of Diagnosed and Undiagnosed Diabetes in Native Hawaiian and Asian American Hospitalized Patients [0.03%]
夏威夷土著人和亚洲美国住院患者中已诊断和未诊断糖尿病的负担
T L Sentell,Y Cheng,E Saito et al.
T L Sentell et al.
Aims: Little is known about diabetes in hospitalized Native Hawaiians and Asian Americans. We determined the burden of diabetes (both diagnosed and undiagnosed) among hospitalized Native Hawaiian, Asian (Filipino, Chinese...
Beneficial paracrine effects of adipocytes from obese rats on cultured endothelial cells [0.03%]
肥胖大鼠脂肪细胞对培养内皮细胞的有益旁分泌效应
Nathan T Jenkins,Jaume Padilla,M Harold Laughlin
Nathan T Jenkins
The purpose was to test the hypothesis that adipocytes from obese rats would exert pro-atherogenic paracrine effects on cultured endothelial cells compared to adipocytes from lean rats, and that the adverse obesity-associated paracrine effe...
Comprehensive assessment of expression of insulin signaling pathway components in subcutaneous adipose tissue of women with and without polycystic ovary syndrome [0.03%]
多囊卵巢综合征患者和非多囊卵巢综合征患者皮下脂肪组织中胰岛素信号通路成分表达的全面评估
Ning Xu,David H Geller,Michelle R Jones et al.
Ning Xu et al.
Objective: Insulin resistance is a common feature of polycystic ovary syndrome (PCOS). The insulin signaling pathway consists of two major pathways, the metabolic and the mitogenic cascades. The many components of these p...
Circulating levels of fibroblast growth factor-21 increase with age independently of body composition indices among healthy individuals [0.03%]
健康人在排除体质指数影响后血清胰岛素生长因子-21的水平随年龄增高而增加
Lynae J Hanks,Orlando M Gutiérrez,Marcas M Bamman et al.
Lynae J Hanks et al.
Background: Circulating FGF21 levels are commonly elevated in disease states. There is limited information regarding concentrations of circulating FGF21 in the absence of disease, as well as age-related differences in bod...
Vitamin D Status, Receptor Gene Polymorphisms, and Supplementation on Tuberculosis: A Systematic Review of Case-Control Studies and Randomized Controlled Trials [0.03%]
维生素D状态、受体基因多态性及补充剂对结核病的影响：病例对照研究和随机双盲试验的系统综述
Nilay Sutaria,Ching-Ti Liu,Tai C Chen
Nilay Sutaria
Objective: To investigate the impacts of vitamin D status, supplementation and vitamin D receptor (VDR) gene polymorphisms on tuberculosis (TB). Methods: ...
Kiran B Hebbar,Michael Wittkamp,Jessica A Alvarez et al.
Kiran B Hebbar et al.
Introduction: The potential role for vitamin D in infection has been well described in adults. The objective of our study was to determine the prevalence of vitamin D insufficiency and to evaluate the relationship between...
Thyrotoxicosis of Pregnancy [0.03%]
妊娠期毒甲状腺症
Artak Labadzhyan,Gregory A Brent,Jerome M Hershman et al.
Artak Labadzhyan et al.
Thyrotoxicosis presenting during pregnancy is a common clinical problem and can be challenging to differentiate between physiologic patterns of thyroid dysfunction during gestation and intrinsic hyperthyroidism. This review provides a summa...
The role of vitamin D in regulating the iron-hepcidin-ferroportin axis in monocytes [0.03%]
维生素D在单核细胞中铁-血色素沉着病素-铁转运蛋白轴调节中的作用
Susu M Zughaier,Jessica A Alvarez,John H Sloan et al.
Susu M Zughaier et al.
Chronic kidney disease affects 40% of adults aged 65 and older. Anemia of CKD is present in 30% of patients with CKD and is associated with increased cardiovascular risk, decreased quality of life, and increased mortality. Hepcidin-25 (hepc...
Metabolomic Analysis Reveals Amino Acid Responses to an Oral Glucose Tolerance Test in Women with Prior History of Gestational Diabetes Mellitus [0.03%]
代谢组学分析揭示了之前患有妊娠期糖尿病妇女口服葡萄糖耐量试验中的氨基酸响应情况
R Bentley-Lewis,G Xiong,H Lee et al.
R Bentley-Lewis et al.
Objective: Although gestational diabetes mellitus (GDM) is associated with an increased risk of type 2 diabetes mellitus (T2DM) compared to normoglycemic pregnancies, the biochemical pathways underlying the progression of...