Michaela B Smith,Joshua Chou,Dikaia Xenaki et al.
Michaela B Smith et al.
Humans are returning to the moon and understanding the toxicity of lunar dust is crucial for successful missions. Apollo mission reports suggest that lunar dust poses significant inhalation risks. Previous studies on lunar dust simulants ha...
Comparative Study
Life sciences in space research. 2025 May:45:72-80. DOI:10.1016/j.lssr.2025.02.005 2025
Mouse hindlimb unloading, as a model of simulated microgravity, leads to dysregulated iron homeostasis in liver and skeletal muscle cells [0.03%]
模拟微重力导致拟南芥铁稳态紊乱
Bilal Rah,Jasmin Shafarin,Rizwan Qaisar et al.
Bilal Rah et al.
Microgravity exposure can impact various physiological systems, yet its specific effects on liver cells remain inadequately studied. To address this gap, we used a hindlimb unloading (HU) mouse model to simulate microgravity conditions and ...
Effects of X-ray irradiation and housing conditions on mitochondria in Peromyscus maniculatus [0.03%]
射线照射和饲养条件对曼氏鼠（草原鹿鼠）线粒体的影响
Agata M Rudolf,Emma M Rhodes,KayLene Yh Yamada et al.
Agata M Rudolf et al.
Challenging environmental conditions, such as exposure to ionizing radiation, can induce oxidative stress within mitochondria. However, organisms show variation in their capacity to cope with cellular stress. This study aimed to identify ho...
Non-DNA radiosensitive targets that initiate persistent behavioral deficits in rats exposed to space radiation [0.03%]
辐射暴露下非DNA放射敏感靶点引发大鼠持续性行为障碍的机制研究
Tore Straume,Ana M Mora,James B Brown et al.
Tore Straume et al.
Predicting future CNS risks for astronauts during deep-space missions will rely substantially on ground-based rodent data with space-relevant ions and behaviors. For rats, the accumulated evidence indicates that less densely ionizing radiat...
Research on the effects of 15-day of head-down tilt bed rest on arterial hemodynamics and blood supply using Doppler ultrasound technology [0.03%]
头斜下卧位床休息导致动脉血流动力学及血液重新分布的研究
Chao Sun,Li Ding,Qing Zhang et al.
Chao Sun et al.
Prolonged exposure to microgravity would cause cardiovascular deconditioning in astronauts, leading to physiological discomfort, decreased cognitive function, and reduced work efficiency. This study aims to explore the hemodynamic effects o...
Status update of NASAs assessment of the biological contamination threat of crewed mars surface missions [0.03%]
NASA载人火星任务生物污染风险评估报告更新
Bette Siegel,J Andy Spry,Elaine Seasly et al.
Bette Siegel et al.
As we prepare for a future first mission to Mars with a human crew, the United States, under the Outer Space Treaty of 1967, has an obligation to protect against harmful contamination of the red planet and to protect the Earth from the pote...
Involvement of KATANIN1, a microtubule-severing enzyme, in hypergravity-induced modification of growth anisotropy in Arabidopsis hypocotyls [0.03%]
参与调控拟南芥下胚轴高重力诱导生长各向异性的微管切割酶KATANIN1的功能分析
Takayuki Hattori,Sayoko Hishii-Higuchi,Hiroko Inoue et al.
Takayuki Hattori et al.
The mechanism by which gravity affects the growth anisotropy of plant organs is an important issue for the cultivation of plants under microgravity conditions in space. This study aimed to examine the roles of KATANIN1 (KTN1), a microtubule...
Characterization of virulence-related phenotypes of Candida parapsilosis and Rhodotorula mucilaginosa isolated from the International Space Station (ISS) [0.03%]
从国际空间站(ISS)分离的Candida parapsilosis和Rhodotorula mucilaginosa的毒力相关表型特征分析
Lauren Wilson,Kaitlyn Nielsen,Stefani Caspasso-Villanueva et al.
Lauren Wilson et al.
There is increased interest in characterizing and describing the effects of space stressors on human microflora. This study describes virulence-related phenotypes of two human yeast commensals, Rhodotorula mucilaginosa and Candida parapsilo...
The effect of Hydrogen-rich water on retinal degeneration in the outer nuclear layer of simulated weightlessness rats [0.03%]
富氢水对模拟失重状态下的外核层视网膜退行性变的影响研究
Yuxue Mu,Weihang Li,Dongyu Wei et al.
Yuxue Mu et al.
Long-term spaceflight can lead to changes in eye structure and decreased visual function. At present, there are almost no effective methods to prevent and treat eye damage caused by microgravity environments. Oxidative stress has been ident...
Molecular and biomechanical changes of the cornea and lens in spaceflight [0.03%]
载人航天中的角膜和晶状体的分子及生物力学变化
Nicholas Panzo,Hamza Memon,Joshua Ong et al.
Nicholas Panzo et al.