Tryptophan metabolites are altered when Caco-2 cells are exposed to simulated microgravity [0.03%]
色氨酸代谢物在Caco-2细胞模拟微重力条件下发生变化
Giulia Tolle,Amalia Di Petrillo,Massimo Claudio Fantini et al.
Giulia Tolle et al.
Microgravity, as experienced during spaceflights, can disrupt cellular function and metabolism, including critical pathways such as tryptophan metabolism. This study investigates how simulated microgravity influences the tryptophan pathway ...
Sleep deprivation and glymphatic dysfunction: Perspectives on the risk of Spaceflight Associated Neuro-ocular Syndrome (SANS) [0.03%]
睡眠剥夺与glymphatic功能障碍：关于空间飞行相关性神经一眼部综合征(SANS)风险的观点
Peter Wostyn,Maiken Nedergaard
Peter Wostyn
Goldfish regenerated scale culture at low temperatures improves osteoblast and osteoclast survival in scales without loss of the osteoblast and osteoclast response to changes in gravity [0.03%]
低温下金鱼再生鳞片培养改善了骨细胞和破骨细胞的存活并保持其对重力变化反应能力
Nobuo Suzuki,Kouhei Kuroda,Mika Ikegame et al.
Nobuo Suzuki et al.
Biological samples that can be stored for long periods are desirable for experiments in space because of the potential for postponement of space vehicle launches. In this study, we determined whether culturing goldfish scales at lower tempe...
Parabolic flight as a space-flight analogon impacts angiogenesis and lipid metabolism [0.03%]
抛物线飞行作为太空飞行的模拟对血管生成和脂质代谢的影响
Vera Paar,Elke Boxhammer,Fitore Marmullaku et al.
Vera Paar et al.
This study aimed to examine the effects of weightlessness and microgravity, induced by parabolic flight, on specific biomarkers associated with angiogenesis, lipid homeostasis, and cardiovascular diseases, including angiogenin (ANG), angiop...
Regulatory measures for mitigating physical and mental health impacts in aerospace environment: A systematic review [0.03%]
航空航天环境下的生理和心理健康影响的缓解监管措施：系统性综述
Rong Liang,Jing Gao,Xiaohui Liu et al.
Rong Liang et al.
Long-term spaceflight poses significant challenges to astronauts' physical and mental health, resulting in physiological issues such as osteoporosis, muscle atrophy, and cardiovascular dysfunction, as well as psychological problems like dep...
Parabolic flight as a research platform to investigate ophthalmic changes in microgravity [0.03%]
利用抛物线飞行研究微重力环境下的眼病变化机制
Tuan Nguyen,Joshua Ong,Sarah Aman et al.
Tuan Nguyen et al.
Parabolic flight serves as an important terrestrial analog to study acute physiological changes in microgravity without the need for space travel. During a parabolic flight, alternating hypergravity and microgravity phases, lasting up to 40...
Changes of iron dynamics in the duodenum and bone marrow under partial gravity condition in mice [0.03%]
小鼠在部分重力条件下十二指肠和骨髓中铁动力学的变化
Yasumasa Ikeda,Masafumi Funamoto,Mizuho Yamamoto et al.
Yasumasa Ikeda et al.
Background: With the advancement of the space age, research on physiological changes during long-term space missions has become increasingly important. Spaceflight-induced anemia, along with muscle and bone loss, is a sig...
Activation of the visual system by space radiation: A novel study on Ca2+ signalling in ex-vivo rabbit eyes exposed to visible light, X-rays and high-energy protons [0.03%]
宇宙射线激活视觉系统的小动物眼实验研究
I Borromeo,A Mentana,G Baiocco et al.
I Borromeo et al.
Space radiation interactions with the visual system have been the subject of many investigations, starting from astronauts reporting the perception of light flashes (visual illusions in absence of light stimuli). These perceptions have been...
Analysis of suitable site candidates for Mars human habitat and life-support technologies based on in situ water resource utilization [0.03%]
基于就地利用火星水资源的人类栖息地及生命保障技术适用性分析研究
Xi Zeng,Hang Wu,Yinuo Xu et al.
Xi Zeng et al.
Human mission to Mars endowed with multiplex challenges has attracted global attentions in the space field. Life support technology is one of the key technologies for deep space exploration, which distinguishes human missions from unhuman o...
Solid rocket motor insulation adhesives with sporicidal activity promote planetary protection for deep space missions [0.03%]
具有杀菌作用的固体火箭发动机绝缘粘合剂可促进深空任务的行星保护
Natalie R Williams,Morgan R Sisk,Thomas P Lampton et al.
Natalie R Williams et al.
To prevent microbial contamination of extraterrestrial biospheres, NASA has established planetary protection requirements for spacecraft bioburden reduction. For missions to land on the icy moons of the outer planets, solid rocket motors (S...