Neuroprotective and neuromodulatory role of agmatine in mitigating simulated microgravity-induced cognitive and behavioral deficits in rats [0.03%]
aggarin在缓解模拟微重力引起的大鼠认知和行为缺陷中的神经保护作用和神经调节作用
Pankaj Neje,Sayli Kulkarni,Shalakha Dabhekar et al.
Pankaj Neje et al.
Extended periods of microgravity during orbital flights can impair astronauts' cognitive abilities, including learning and memory, posing a persistent health concern in the field of aerospace medicine. The study examined the pharmacological...
Exposing Drosophila to wheat-derived microbes enhances its immunity and survival under simulated microgravity [0.03%]
暴露于小麦来源微生物可增强果蝇模拟微重力环境下的免疫力和存活率
Letian Chen,Shijing Wang,Chuanmeng Cai et al.
Letian Chen et al.
During prolonged space habitation, microgravity compromises astronaut immunity, increasing the risk of infectious diseases. Plant-derived microbes offer a promising strategy for enhancing immunity, yet their feasibility and mechanisms remai...
Effects of the space environment and re-adaptation to Earth's gravity on astronauts' plasma proteome [0.03%]
空间环境及重新适应地球重力对航天员血浆蛋白质组成的影响
Kanokporn Rithidech,Rodrigo Mohallem,Uma K Aryal et al.
Kanokporn Rithidech et al.
We performed a label-free quantitative plasma proteomic analysis on samples from eight astronauts who completed a 6-month mission aboard the International Space Station, using an Orbitrap Fusion Lumos mass spectrometer (MS). Blood samples w...
Pinoresinol diglucoside alleviates hindlimb unloading-induced bone loss in mice [0.03%]
松蒿内酯葡萄糖苷缓解小鼠失重诱导的骨丢失作用研究
Ying-Ying Xuan,Liang Li,Yi Wu et al.
Ying-Ying Xuan et al.
Microgravity-induced bone loss has long been a critical issue in space exploration. While countermeasures have been suggested, none have achieved the desired effects. Pinoresinol diglucoside (PDG), an effective constituent of the medicinal ...
Protective effects of compound Gastrodia elata formula on the cognitive impairment induced by simulated weightlessness in mice [0.03%]
天麻复方对模拟失重诱发小鼠认知障碍的保护作用
Fang Chen,Ning Jiang,Muhammad Noman Khan et al.
Fang Chen et al.
Growing evidence highlights that long-term orbital flight may lead to structural changes in brains and cognitive impairments in astronauts. However, effective strategies to counteract these effects remain limited. Compound Gastrodia elata F...
3D culture and cryopreservation/thawing strategy of human induced pluripotent stem cells for spaceflight experiments [0.03%]
人诱导多能干细胞的三维培养和太空飞行实验解冻保存策略研究
Jingtong Xie,Chiyuan Ma,Yanbang Wei et al.
Jingtong Xie et al.
Background: Although current space-based cell biology experiments predominantly rely on two-dimensional (2D) culture systems combined with in-orbit chemical fixation protocols, the development of a stem cell three-dimensi...
Digital twin modelling in microgravity: A framework for predictive and personalised space medicine [0.03%]
微重力下的数字孪生建模：预测性和个性化的空间医学框架
Ruqaiyyah Siddiqui,Rizwan Qaisar,Adel Elmoselhi et al.
Ruqaiyyah Siddiqui et al.
Human spaceflight exposes the body to a complex array of physiological stressors that collectively alter cardiovascular, musculoskeletal, immune, and nervous systems. Continuous biomedical monitoring produces vast, but fragmented datasets i...
Yodying Yingchutrakul,Tatpong Tulyananda,Sucheewin Krobthong
Yodying Yingchutrakul
Space agriculture is pivotal for sustaining long-duration space missions by providing fresh food, oxygen, and waste recycling capabilities. This review evaluates advanced omics strategies that elucidate how plants adapt to the extreme condi...
Enhanced accuracy in radiation dose estimation for astronauts using mesh-type reference computational phantoms [0.03%]
基于网格的人体模体的辐射剂量计算及其精度改善研究
Vivek Kaushik,Sabyasachi Paul,Sunder Sahayanathan et al.
Vivek Kaushik et al.
With the increasing ambition of deep space missions, the accurate estimation of radiation doses to astronauts has become a critical concern. Traditional radiation dose estimation methods may often overestimate the biological impact due to t...
International space station external radiation field as measured by Liulin-SET spectrometer of ARMAS flight module 9 in September - October 2022 [0.03%]
2022年9月至10月国际空间站外部辐射场的Liulin-SET光谱仪测量结果（ARMAS飞行舱段9号）
Tsvetan Dachev,W Kent Tobiska,Borislav Tomov et al.
Tsvetan Dachev et al.
The Liulin-SET spectrometer, developed at the Space Research and Technology Institute of the Bulgarian Academy of Sciences, was integrated with the Automated Radiation Measurements for Aerospace Safety (ARMAS) Flight Module Number 9 (FM9). ...