E-Health & Innovation to Overcome Barriers in Neuromuscular Diseases. Report from the 1st eNMD Congress: Nice, France, March 22-23, 2019 [0.03%]
用于克服神经肌肉疾病障碍的电子医疗和创新．来自2019年3月22日至23日在法国尼斯举行的首届eNMD大会报告
Jonathan Pini,Gabriele Siciliano,Pauline Lahaut et al.
Jonathan Pini et al.
By definition, neuromuscular diseases are rare and fluctuating in terms of symptoms; patients are often lately diagnosed, do not have enough information to understand their condition and be proactive in their management. Usually, insufficie...
Free-Living Physical Activity and Sedentary Behaviour in Autoimmune Myasthenia Gravis: A Cross-Sectional Study [0.03%]
自身免疫性重症肌无力中的无约束体力活动和久坐行为：一项横断面研究
Simone Birnbaum,Damien Bachasson,Tarek Sharshar et al.
Simone Birnbaum et al.
Background: Muscle weakness and fatigability, the prominent symptoms of autoimmune myasthenia gravis (MG), negatively impact daily function and quality of life (QoL). It is currently unclear as to what extent symptoms lim...
Characterization of Adult Patients With SMA Treated in US Hospital Settings: A Natural History Study in the Premier Healthcare Database [0.03%]
美国医院环境中接受治疗的成人SMA患者特征：来至Premier卫生保健数据库的自然史研究
Nicole B Johnson,Crystal Proud,Christina L Wassel et al.
Nicole B Johnson et al.
Background: Spinal muscular atrophy (SMA) is a rare genetic disease characterized by progressive muscular weakness and atrophy resulting from motor neuron degeneration. Limited information is available on disease progress...
Observational Study
Journal of neuromuscular diseases. 2021;8(4):569-578. DOI:10.3233/JND-200624 2021
Histological Analysis of Tibialis Anterior Muscle of DMDmdx4Cv Mice from 1 to 24 Months [0.03%]
DMDmdx4Cv小鼠1至24月龄胫前肌的组织学分析
Sabrina Ben Larbi,Marielle Saclier,Aurélie Fessard et al.
Sabrina Ben Larbi et al.
Background: The mdx-C57/B6 mouse model does not show the clinical signs of Duchenne muscular dystrophy (DMD), although muscles exhibit hallmarks of permanent regeneration and alterations in muscle function. The DMDmdx4Cv ...
Quantitative Muscle-MRI Correlates with Histopathology in Skeletal Muscle Biopsies [0.03%]
定量肌肉MRI与骨骼肌活检的病理组织学相关性研究
Anne-Katrin Güttsches,Robert Rehmann,Anja Schreiner et al.
Anne-Katrin Güttsches et al.
Background: Skeletal muscle biopsy is one of the gold standards in the diagnostic workup of muscle disorders. By histopathologic analysis, characteristic features like inflammatory cellular infiltrations, fat and collagen...
Oxaliplatin Neuropathy: Predictive Values of Skin Biopsy, QST and Nerve Conduction [0.03%]
奥沙利铂神经病变：皮肤活检、QST和神经传导预测价值
Thomas Krøigård,Toke K Svendsen,Martin Wirenfeldt et al.
Thomas Krøigård et al.
Background: Oxaliplatin-induced peripheral neuropathy negatively affects the quality of life for patients with gastrointestinal cancers and may cause neuropathic pain. Measures of peripheral nerve structure or function, s...
Vitamin D Level Stability in Dystrophinopathy Patients on Vitamin D Supplementation [0.03%]
维生素D补充对 Duchenne 肌营养不良患者维生素D水平稳定性的影响
Naomi Vather-Wu,Matthew D Krasowski,Katherine D Mathews et al.
Naomi Vather-Wu et al.
Background: Expert guidelines recommend annual monitoring of 25-hydroxyvitamin D (25-OHD) and maintaining 25-OHD ≥30 ng/ml in patients with dystrophinopathies. ...
Improved Cardiac Outcomes by Early Treatment with Angiotensin-Converting Enzyme Inhibitors in Becker Muscular Dystrophy [0.03%]
贝克尔型肌营养不良症早期使用血管紧张素转换酶抑制剂改善心脏预后
Caroline Stalens,Leslie Motté,Anthony Béhin et al.
Caroline Stalens et al.
Background: The latest practice guidelines from the American College of Cardiology/American Heart Association recommend the prescription of an ACE-i for patients presenting with non-ischemic cardiomyopathy when left ventr...
Multicenter Study
Journal of neuromuscular diseases. 2021;8(4):495-502. DOI:10.3233/JND-200620 2021
Clinical Management of Duchenne Muscular Dystrophy in the Netherlands: Barriers to and Proposals for the Implementation of the International Clinical Practice Guidelines [0.03%]
荷兰杜氏肌营养不良临床管理国际实践指南的实施困境及对策
Lotte Heutinck,Maaike van Gameren,Jan J G M Verschuuren et al.
Lotte Heutinck et al.
Background: In order to successfully implement the international clinical care guidelines for Duchenne muscular dystrophy (DMD) in the Netherlands, it is essential to know what barriers are experienced by healthcare pract...
Evaluation of the Lipid-binding Properties of Recombinant Dystrophin Spectrin-like Repeat Domains R1-3 [0.03%]
重组 dystrophin 补体样重复结构域 R1-3 结合脂质特性的评估研究
Grace Cooper-Olson,Louise R Rodino-Klapac,Rachael A Potter
Grace Cooper-Olson
Recombinant micro-dystrophin genes are designed to treat Duchenne muscular dystrophy (DMD) by retaining dystrophin domains believed to play key functional roles while fitting the packaging capacity of adeno-associated virus vectors. Domains...