Antiviral and cytotoxic effects of a traditional drug KanthaRasaVillai with a cocktail of metallic nanoparticles [0.03%]
传统药物KanthaRasaVillai及金属纳米颗粒鸡尾酒的抗病毒和细胞毒性作用
Amirtham J A Ranjitsingh,Sandhanasamy Devanesan,Mohamad S AlSalhi et al.
Amirtham J A Ranjitsingh et al.
Objective: Alternative medicine plays an important role today in searching for therapeutics for cancer and viral infection. So, a scientific validation to characterize constituents in the alternative medicines and therape...
Effect of environmental pollutants PM2.5, CO, O3 and NO2, on the incidence and mortality of SARS-COV-2 in largest metropolitan cities, Delhi, Mumbai and Kolkata, India [0.03%]
环境污染物PM2.5、CO、O3和NO2对印度三大都市区德里、孟买和加尔各答的SARS-COV-2发病率和死亡率的影响
Sultan Ayoub Meo,Sara Ahmed Alqahtani,Fatimah Saad Binmeather et al.
Sultan Ayoub Meo et al.
Objectives: The Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has developed a challenging situation worldwide. In India, the SARS-CoV-2 cases and deaths have markedly increased. This study aims to evaluate ...
SARS-CoV-2 spike protein: Site-specific breakpoints for the development of COVID-19 vaccines [0.03%]
SARS-CoV-2刺突蛋白:用于研发COVID-19疫苗的特异性断裂点
Palaniyandi Velusamy,Kannan Kiruba,Chia-Hung Su et al.
Palaniyandi Velusamy et al.
SARS-CoV2 is a member of human coronaviruses and is the causative agent of the present pandemic COVID-19 virus. In order to control COVID-19, studies on viral structure and mechanism of infectivity and pathogenicity are sorely needed. The s...
Use of non-homogeneous Poisson process for the analysis of new cases, deaths, and recoveries of COVID-19 patients: A case study of Kuwait [0.03%]
非齐次泊松过程在COVID-19新增病例、死亡和康复分析中的应用:以科威特为例
Ahmad Al-Dousari,Asad Ellahi,Ijaz Hussain
Ahmad Al-Dousari
The coronavirus disease spread out rapidly in China and then in the whole world. Kuwait is one of those countries which are positively affected by this pandemic. Objective : The current study aims to provide an appropriate and novel framewo...
Repurposing benzimidazole and benzothiazole derivatives as potential inhibitors of SARS-CoV-2: DFT, QSAR, molecular docking, molecular dynamics simulation, and in-silico pharmacokinetic and toxicity studies [0.03%]
苯并咪唑和苯并噻唑衍生物作为SARS-CoV-2潜在抑制剂的再利用:DFT、QSAR、分子对接、分子动力学模拟以及基于计算机的药代动力学和毒性研究
Ranjan K Mohapatra,Kuldeep Dhama,Amr Ahmed El-Arabey et al.
Ranjan K Mohapatra et al.
Density Functional Theory (DFT) and Quantitative Structure-Activity Relationship (QSAR) studies were performed on four benzimidazoles (compounds 1-4) and two benzothiazoles (compounds 5 and 6), previously synthesized by our group. The compo...
A review on Saudi Arabian wastewater treatment facilities and available disinfection methods: Implications to SARS-CoV-2 control [0.03%]
沙特阿拉伯污水处理设施及可用消毒方法的评述:对SARS-CoV-2控制的影响
Hadil M Alahdal,Sami AlYahya,Fuad Ameen et al.
Hadil M Alahdal et al.
COVID-19 pandemic has severe impacts on human health and economy worldwide. Aerosols and droplets are the major routes of transmission of SARS-CoV-2 coronavirus causing COVID-19 disease. However, wastewater is a possible transmission pathwa...
Development of in-house ELISAs for the detection of anti-SARS‑CoV‑2 RBD and N IgG and IgM antibodies in biological samples [0.03%]
开发针对生物样本中的SARS-CoV-2 RBD和N IgG及IgM抗体的内部ELISA检测方法
Essam H Ibrahim,Hamed A Ghramh,Mona Kilany
Essam H Ibrahim
By the end of year 2019, the new virus SARS-CoV-2 appeared, causing the Coronavirus Disease 2019 (COVID-19), and spread very fast globally. A continuing need for diagnostic tools is a must to contain its spread. Till now, the gold standard ...
Effect of environmental pollution PM2.5, carbon monoxide, and ozone on the incidence and mortality due to SARS-CoV-2 infection in London, United Kingdom [0.03%]
环境污染物PM2.5、一氧化碳和臭氧对英国伦敦新冠肺炎发病及死亡的影响研究
Sultan Ayoub Meo,Abdulelah Adnan Abukhalaf,Waqas Sami et al.
Sultan Ayoub Meo et al.
Objectives: COVID-19 pandemic raised several queries on the relationship between the environment pollution and occurrence of new cases and deaths. This study aims to explore the effect of environmental pollution, particul...
Seroprevalence of neutralizing antibodies to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) among healthcare workers in Makkah, Saudi Arabia [0.03%]
沙特麦加地区医护人员严重急性呼吸系统综合征冠状病毒2(Il6NCoV-2)中和抗体血清流行病学调查结果
Waleed A Ahmed,Ashraf Dada,Abeer N Alshukairi et al.
Waleed A Ahmed et al.
Objective: The new coronavirus disease 2019 (COVID-19) is a major health problem worldwide. The surveillance of seropositive individuals serves as an indicator to the extent of infection spread and provides an estimation ...
Combined docking methods and molecular dynamics to identify effective antiviral 2, 5-diaminobenzophenonederivatives against SARS-CoV-2 [0.03%]
结合对接方法和分子动力学识别针对SARS-CoV-2的有效抗病毒2,5-二氨基苯并茋衍生物
Mebarka Ouassaf,Salah Belaidi,Muneerah Mogren Al Mogren et al.
Mebarka Ouassaf et al.
The aim of this work is to contribute to the research in finding lead compounds for clinical use, to identify new drugs that target the SARS-CoV-2 virus main protease (Mpro). In this study, we used molecular docking strategies to analyze 2....