Effect of insilico predicted and designed potential siRNAs on inhibition of SARS-CoV-2 in HEK-293 cells [0.03%]
体外预测和设计的潜在siRNA抑制SARS-CoV-2感染HEK-293细胞的效果研究
Sayed Sartaj Sohrab,Sherif Aly El-Kafrawy,Esam Ibraheem Azhar
Sayed Sartaj Sohrab
Objectives: The COVID-19 was identified for the first time from the sea food market, Wuhan city, China in 2019 and the pathogenic organism was identified as SARS-CoV-2. Currently, this virus has spread to 223 countries an...
Evaluating the structural and immune mechanism of Interleukin-6 for the investigation of goat milk peptides as potential treatments for COVID-19 [0.03%]
评估白细胞介素-6的结构和免疫机制以调查山羊奶肽作为COVID-19潜在治疗方法的研究
Sundaresan Bhavaniramya,Ashokkumar Sibiya,Abdulaziz S Alothaim et al.
Sundaresan Bhavaniramya et al.
The function of Immune control, haematopoiesis, and inflammation all depend on the cytokine Interleukin 6 (IL-6), and higher expression of IL-6 is seen in COVID-19 and other diseases. The immune protein IL-6 activation is dependent on bindi...
Neurological complications of COVID-19 in children and the associated immunological responses [0.03%]
儿童新冠患者的神经系统并发症及其相关免疫反应
Rabeea Siddique,Suliman Khan,Shabana et al.
Rabeea Siddique et al.
The high spread rate, severe symptoms, psychological and neurological problems, and unavailability of effective medicines are the major factors making Coronavirus disease 2019 (COVID-19) a massive threat to the world. It is thought that COV...
A new study on two different vaccinated fractional-order COVID-19 models via numerical algorithms [0.03%]
基于数值算法的两种不同疫苗接种分数阶COVID-19模型的新研究
Anwar Zeb,Pushpendra Kumar,Vedat Suat Erturk et al.
Anwar Zeb et al.
The main purpose of this paper is to provide new vaccinated models of COVID-19 in the sense of Caputo-Fabrizio and new generalized Caputo-type fractional derivatives. The formulation of the given models is presented including an exhaustive ...
Efficient multimodal deep-learning-based COVID-19 diagnostic system for noisy and corrupted images [0.03%]
一种针对噪声和损坏图像的高效多模态深度学习COVID-19诊断系统
Mohamed Hammad,Lo&#x;ai Tawalbeh,Abdullah M Iliyasu et al.
Mohamed Hammad et al.
Introduction: In humanity's ongoing fight against its common enemy of COVID-19, researchers have been relentless in finding efficient technologies to support mitigation, diagnosis, management, contact tracing, and ultimat...
Design & discovery of small molecule COVID-19 inhibitor via dual approach based virtual screening and molecular simulation studies [0.03%]
基于虚拟筛选和分子模拟研究的COVID-19小分子抑制剂的设计与发现
Nada H Aljarba,Md Saquib Hasnain,Mashael Mohammed Bin-Meferij et al.
Nada H Aljarba et al.
The emerged COVID-19 (SARS corona virus) pandemic leads to severe or fatal respiratory tract infections affecting millions of people worldwide since its outbreak. The situation needs the newer molecule to control the infections as the pande...
Identification of bioactive molecules from Triphala (Ayurvedic herbal formulation) as potential inhibitors of SARS-CoV-2 main protease (Mpro) through computational investigations [0.03%]
通过计算研究识别三仙果（印度阿育吠陀草药配方）中_bioactive_分子作为SARS-CoV-2主要蛋白酶（Mpro）的潜在抑制剂
Mithun Rudrapal,Ismail Celik,Johra Khan et al.
Mithun Rudrapal et al.
Severe acute respiratory syndrome coronavirus disease (SARS-CoV-2) induced coronavirus disease 2019 (COVID-19) pandemic is the present worldwide health emergency. The global scientific community faces a significant challenge in developing t...
Artesunate induces substantial topological alterations in the SARS-CoV-2 Nsp1 protein structure [0.03%]
艺术甜素通过显着的拓扑变化改变SARS-CoV-2 Nsp1蛋白结构
Arun Bahadur Gurung,Mohammad Ajmal Ali,Joongku Lee et al.
Arun Bahadur Gurung et al.
The need for novel antiviral treatments for coronavirus disease 2019 (COVID-19) continues with the widespread infections and fatalities throughout the world. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent ...
Structural and functional insights into the major mutations of SARS-CoV-2 Spike RBD and its interaction with human ACE2 receptor [0.03%]
关于SARS-CoV-2刺突RBD主要突变的结构与功能见解及其与人类ACE2受体的作用模式探究
Arun Bahadur Gurung,Mohammad Ajmal Ali,Joongku Lee et al.
Arun Bahadur Gurung et al.
Coronavirus Disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has rapidly spread around the world jeopardizing the global economy and health. The rapid proliferation and infectivity of the virus ...
Molecular docking and dynamics studies on propolis sulabiroin-A as a potential inhibitor of SARS-CoV-2 [0.03%]
蜂胶素A作为SARS-CoV-2潜在抑制剂的分子对接和动力学研究
Jaka Fajar Fatriansyah,Raihan Kenji Rizqillah,Muhamad Yusup Yandi et al.
Jaka Fajar Fatriansyah et al.
Molecular docking and dynamics simulations were conducted to investigate the antiviral activity of Propolis Sulabiroin-A to inhibit the SARS-CoV-2 virus with quercetin, hesperidin, and remdesivir as control ligands. The parameters calculate...