Recovery of Hippocampal-Dependent Learning Despite Blunting Reactive Adult Neurogenesis After Alcohol Dependence [0.03%]
酒精依赖后尽管抑制了反应性成人神经发生但仍能恢复海马依赖型学习能力
Chelsea G Nickell,K Ryan Thompson,James R Pauly et al.
Chelsea G Nickell et al.
Background: The excessive alcohol drinking that occurs in alcohol use disorder (AUD) causes neurodegeneration in regions such as the hippocampus, though recovery may occur after a period of abstinence. Mechanisms of recov...
Functional and Structural Correlates of Impaired Enrichment-Mediated Adult Hippocampal Neurogenesis in a Mouse Model of Prenatal Alcohol Exposure [0.03%]
孕期酒精暴露小鼠模型中受损的丰富刺激介导的成年海马神经发生的功能和结构相关因素
Kymberly Gustus,Lu Li,Jessie Newville et al.
Kymberly Gustus et al.
Background: Fetal alcohol spectrum disorders (FASDs) are associated with a wide range of cognitive deficiencies. Objective: We previous...
Tumour Necrosis Factor in Neuroplasticity, Neurogenesis and Alcohol Use Disorder [0.03%]
肿瘤坏死因子与神经可塑性、神经发生及酒精使用障碍的关系
Ignatius Alvarez Cooper,Kate Beecher,Fatemeh Chehrehasa et al.
Ignatius Alvarez Cooper et al.
Alcohol use disorder is a pervasive and detrimental condition that involves changes in neuroplasticity and neurogenesis. Alcohol activates the neuroimmune system and alters the inflammatory status of the brain. Tumour necrosis factor (TNF) ...
Alcohol and Cocaine Combined Substance Use on Adult Hypothalamic Neural Stem Cells and Neurogenesis [0.03%]
酒精和可卡因联合使用对成人下丘脑神经干细胞和神经发生的影响
Caitlin R Schlagal,Ping Wu
Caitlin R Schlagal
Many advancements have been made over the years looking at the individual and combined effects of drugs of abuse on the brain, with one key area of research focusing on the effects on neurogenesis. An integral part of fetal brain developmen...
Sreetama Basu,Hoonkyo Suh
Sreetama Basu
Chronic alcohol consumption results in alcohol use disorder (AUD). Interestingly, however, sudden alcohol withdrawal (AW) after chronic alcohol exposure also leads to a devastating series of symptoms, referred to as alcohol withdrawal syndr...
Sex and Age Effects on Neurobehavioral Toxicity Induced by Binge Alcohol [0.03%]
酒精诱发的神经行为毒性的性别和年龄效应分析
Ibdanelo Cortez,Shaefali P Rodgers,Therese A Kosten et al.
Ibdanelo Cortez et al.
Historically, most alcohol neurotoxicity studies were conducted in young adult males and focused on chronic intake. There has been a shift towards studying the effects of alcohol on the adolescent brain, due to alcohol consumption during th...
Cardiorespiratory Fitness Associates with Cerebral Vessel Pulsatility in a Cohort Enriched with Risk for Alzheimer's Disease [0.03%]
cardiorespiratory fitness与阿尔茨海默病风险关系的一项队列研究中的脑血管搏动性相关性
Kaitlin M Maxa,Carson Hoffman,Leonardo A Rivera-Rivera et al.
Kaitlin M Maxa et al.
Background: There is increasing evidence that vascular disease risk factors contribute to evolution of the dementia syndrome of Alzheimer's disease (AD). One important measure of cerebrovascular health is pulsatility inde...
The Effect of Aerobic Exercise on Physical and Cognitive Outcomes in a Small Cohort of Outpatients with Schizophrenia [0.03%]
有氧运动对一组精神分裂症门诊患者身体和认知结果的影响
Nicholas Massa,Alaaeddin Alrohaibani,Kevin Mammino et al.
Nicholas Massa et al.
Background: Schizophrenia (SCZ) is a severe, chronic illness characterized by psychotic symptoms and impairments in many cognitive domains. Dysregulation of brain derived neurotrophic factor (BDNF) is associated with the ...
Diffusion tensor-MRI detects exercise-induced neuroplasticity in the hippocampal microstructure in mice [0.03%]
扩散张量MRI检测到小鼠海马微结构中运动诱导的神经可塑性
Mohammad R Islam,Renhao Luo,Sophia Valaris et al.
Mohammad R Islam et al.
Background: Despite considerable research on exercise-induced neuroplasticity in the brain, a major ongoing challenge in translating findings from animal studies to humans is that clinical and preclinical settings employ ...
Changes in Hippocampal Androgen Receptor Density and Behavior in Sprague-Dawley Male Rats Exposed to a Low-Pressure Blast Wave [0.03%]
Sprague-Dawley雄性大鼠暴露于低压冲击波后海马Androgen受体密度和行为的变化
Jay R Hoffman,Amitai Zuckerman,Omri Ram et al.
Jay R Hoffman et al.
Objective: The purpose of this study was to examine the effect of exposure of a low-intensity blast wave on androgen receptor (AR) density in the hippocampus and the potential influence on behavioral and cognitive respons...