Transcriptomic Profiling of Primary Alveolar Epithelial Cell Differentiation in Human and Rat [0.03%]
人和大鼠原代肺泡上皮细胞分化转录组分析
Crystal N Marconett,Beiyun Zhou,Kimberly D Siegmund et al.
Crystal N Marconett et al.
Cell-type specific gene regulation is key to gaining a full understanding of how the distinct phenotypes of differentiated cells are achieved and maintained. Here we examined how changes in transcriptional activation during alveolar epithel...
Genome Wide Mapping of Foxo1 Binding-sites in Murine T Lymphocytes [0.03%]
Foxo1结合位点在小鼠T淋巴细胞中的全基因组定位映射
Will Liao,Weiming Ouyang,Michael Q Zhang et al.
Will Liao et al.
The Forkhead box O (Foxo) family of transcription factors has a critical role in controlling the development, differentiation, and function of T cells. However, the direct target genes of Foxo transcription factors in T cells have not been ...
Gene Expression Profiling of Valvular Interstitial Cells in Rapacz Familial Hypercholesterolemic Swine [0.03%]
拉帕奇家族性高胆固醇猪瓣膜间质细胞基因表达谱分析
Ana M Porras,Dhanansayan Shanmuganayagam,Jennifer J Meudt et al.
Ana M Porras et al.
Rapacz familial hypercholesterolemic (RFH) swine are a well-established model of human FH, a highly prevalent hereditary disease associated with increased risk of coronary artery disease and calcific aortic valve disease (CAVD). However, wh...
Transcriptome profiling of Set5 and Set1 methyltransferases: Tools for visualization of gene expression [0.03%]
Set5和Set1甲基转移酶的转录组特征分析：可视化基因表达的方法
Glòria Mas Martín,Devin A King,Pablo E Garcia-Nieto et al.
Glòria Mas Martín et al.
Cells regulate transcription by coordinating the activities of multiple histone modifying complexes. We recently identified the yeast histone H4 methyltransferase Set5 and discovered functional overlap with the histone H3 methyltransferase ...
Brittany S Sexton,Brooke R Druliner,Denis Avey et al.
Brittany S Sexton et al.
In the eukaryotic nucleus, DNA is packaged into chromatin. The fundamental subunit of chromatin is the nucleosome, DNA is wrapped 1.6 times around a histone octamer core. Nuclear processes in eukaryotes are impacted by whether regulatory DN...
Gene expression signatures affected by ethanol and/or nicotine in normal human normal oral keratinocytes (NHOKs) [0.03%]
乙醇和/或尼古丁对正常人口腔角质形成细胞基因表达特征的影响
Jeffrey J Kim,Omar Khalid,Lewei Duan et al.
Jeffrey J Kim et al.
It has been reported that nicotine/alcohol alter epigenetic control and lead to abrogated DNA methylation and histone modifications, which could subsequently perturb transcriptional regulation critically important in cellular transformation...
Genome-wide DNA binding pattern of the homeodomain transcription factor Sine oculis (So) in the developing eye of Drosophila melanogaster [0.03%]
模式节肢动物黑腹果蝇发育中眼基因组结合模式及其同源转录因子Sine oculis( So)的全基因组dna结合模式
Barbara Jusiak,Feng Wang,Umesh C Karandikar et al.
Barbara Jusiak et al.
The eye of the fruit fly Drosophila melanogaster provides a highly tractable genetic model system for the study of animal development, and many genes that regulate Drosophila eye formation have homologs implicated in human development and d...
Molecular effect of ethanol during neural differentiation of human embryonic stem cells in vitro [0.03%]
乙醇对体外分化的人胚胎干细胞的分子影响
Jeffrey J Kim,Lewei Duan,Thanh G Tu et al.
Jeffrey J Kim et al.
Potential teratogenic effects of alcohol on fetal development have been documented. Especially studies have demonstrated deleterious effect of ethanol exposure on neuronal development in animal models and on the maintenance and differentiat...
Genome-Wide Mapping of the Distribution of CarD, RNAP σA, and RNAP β on the Mycobacterium smegmatis Chromosome using Chromatin Immunoprecipitation Sequencing [0.03%]
采用染色质免疫沉淀测序法绘制卡达菌素、RNAP σA 和 RNAP β 在鼠伤寒沙门氏菌基因组中的分布图
Robert Landick,Azra Krek,Michael S Glickman et al.
Robert Landick et al.
CarD is an essential mycobacterial protein that binds the RNA polymerase (RNAP) and affects the transcriptional profile of Mycobacterium smegmatis and Mycobacterium tuberculosis (6). We predicted that CarD was directly regulating RNAP funct...
Genome-wide transcriptomic alterations induced by ethanol treatment in human dental pulp stem cells (DPSCs) [0.03%]
乙醇处理人牙髓干细胞(DPSCs)的转录组变化分析
Omar Khalid,Jeffrey J Kim,Lewei Duan et al.
Omar Khalid et al.
Human dental pulp stem cells (DPSCs) isolated from adult dental pulp are multipotent mesenchymal stem cells that can be directed to differentiate into osteogenic/odontogenic cells and also trans-differentiate into neuronal cells. The utilit...