Jonas Korlach
Jonas Korlach
Genomic data have become commonplace in most branches of the biological sciences and have fundamentally altered the way research is conducted. However, the predominance of short-read sequence data from second-generation sequencing technolog...
Genome sequencing and annotation of Amycolatopsis azurea DSM 43854(T) [0.03%]
产生石松蓝色素链霉菌DSM 43854(T)的基因组测序与注释
Indu Khatri,Srikrishna Subramanian,Shanmugam Mayilraj
Indu Khatri
We report the 9.2 Mb genome of the azureomycin A and B antibiotic producing strain Amycolatopsis azurea isolated from a Japanese soil sample. The draft genome of strain DSM 43854(T) consists of 9,223,451 bp with a G + C content of 69.0% and...
Genome-wide profiling to analyze the effects of high fat diet induced obesity on renal gene expression in mouse with reduced renal mass [0.03%]
减少肾单位的大鼠肾皮质基因表达的全基因组分析：高脂肪饮食诱导的肥胖的影响
Zhibo Gai
Zhibo Gai
To assess the relationship between a reduced nephron number and a particular susceptibility to obesity-induced renal damage, mice underwent uninephrectomy (UNX) followed by either normal chow or high-fat diet (HFD) and were compared with sh...
Genome sequencing, annotation of Citrobacter freundii strain GTC 09479 [0.03%]
芽单胞菌属弗朗迪克菌基因组测序及注释(GTC 09479株)
Kazuyuki Kimura,Shailesh Kumar,Masahiro Takeo et al.
Kazuyuki Kimura et al.
We report the 4.9-Mb genome sequence of Citrobacter freundii strain GTC 09479, isolated from urine sample collected during the year 1983 at Gifu University Graduate School of Medicine, Japan. This draft genome consist of 4,899,578 bp with 5...
Report from the 2nd Summer School in Computational Biology organized by the Queen's University of Belfast [0.03%]
第二届计算生物学暑期学校报告(贝尔法斯特皇后大学主办)
Frank Emmert-Streib,Shu-Dong Zhang,Peter Hamilton
Frank Emmert-Streib
In this paper, we present a meeting report for the 2nd Summer School in Computational Biology organized by the Queen's University of Belfast. We describe the organization of the summer school, its underlying concept and student feedback we ...
Transcriptome analysis of the mouse E14.5 (TS23) developing humerus and differential expression in muscle-less mutant embryos lacking mechanical stimulation [0.03%]
无机械刺激的小鼠E14.5(23体节)发育肱骨转录组分析及肌肉缺失突变胚胎的差异表达
Rebecca A Rolfe,Elaine M Kenny,Paul Cormican et al.
Rebecca A Rolfe et al.
Mechanical stimulation is important for the correct formation of the skeleton. Splotch-delayed mutant embryos (Pax3 (Spd/Spd) ) that develop with no limb muscle and therefore no limb movement experience an altered mechanical environment res...
Colorectal cancer driver genes identified by patient specific comparison of cytogenetic microarray [0.03%]
基于患者特异性染色体微阵列对比鉴定结直肠癌驱动基因
Mohammad Azhar Aziz,Sathish Periyasamy,Zeyad Yousef et al.
Mohammad Azhar Aziz et al.
Colorectal cancer (CRC), which has high prevalence in Saudi Arabia and worldwide, needs better understanding by exploiting the latest available cytogenetic microarrays. We used biopsy tissue from consenting colorectal cancer patients to ext...
Mandy Jayne Peffers,Xuan Liu,Peter David Clegg
Mandy Jayne Peffers
The musculoskeletal system is severely affected by the ageing process, with many tissues undergoing changes that lead to loss of function and frailty. Articular cartilage is susceptible to age related diseases, such as osteoarthritis. Apply...
Dataset of microarray analysis to identify endoglin-dependent bone morphogenetic protein-2-responsive genes in the murine periodontal ligament cell line PDL-L2 [0.03%]
用于识别小鼠牙周韧带细胞系PDL-L2中内源性依赖的骨形态发生蛋白-2应答基因的芯片数据集
Osamu Ishibashi,Takashi Inui
Osamu Ishibashi
The periodontal ligament (PDL), connective tissue located between the cementum of teeth and alveolar bone of the mandibula, plays a crucial role in the maintenance and regeneration of periodontal tissues. We previously reported that endogli...
Genome-wide analysis of SRSF10-regulated alternative splicing by deep sequencing of chicken transcriptome [0.03%]
鸡转录组的深度测序分析SRSF10调控的可变剪接
Xuexia Zhou,Wenwu Wu,Ning Wei et al.
Xuexia Zhou et al.
Splicing factor SRSF10 is known to function as a sequence-specific splicing activator that is capable of regulating alternative splicing both in vitro and in vivo. We recently used an RNA-seq approach coupled with bioinformatics analysis to...