Genome-wide profiling of YY1 binding sites during skeletal myogenesis [0.03%]
在骨骼肌发生过程中进行YY1结合位点的基因组范围谱分析
Kun Sun,Leina Lu,Huating Wang et al.
Kun Sun et al.
Skeletal muscle differentiation is regulated by a network of transcription factors, epigenetic regulators and noncoding RNAs. We have recently performed ChIP-seq experiments to explore the genome-wide binding of transcription factor YY1 in ...
Identification of TEL-AML1 (ETV6-RUNX1) associated DNA and its impact on mRNA and protein output using ChIP, mRNA expression arrays and SILAC [0.03%]
TEL-AML1（ETV6-RUNX1）相关DNA的鉴定及其对mRNA和蛋白质产生的影响：运用ChIP、mRNA表达阵列及SILAC技术研究
Yvonne Linka,Sebastian Ginzel,Arndt Borkhardt et al.
Yvonne Linka et al.
The contribution of the most common reciprocal translocation in childhood B-cell precursor leukemia t(12;21)(p13;q22) to leukemia development is still under debate. Direct as well as secondary indirect effects of the TEL-AML1 fusion protein...
CTCF regulates positioning of the human cystic fibrosis gene in association with a histone deacetylase [0.03%]
染色质重塑因子CTCF调节与组蛋白脱乙酰酶相关的人囊性纤维化基因的定位
Joscha Muck
Joscha Muck
The nuclear positioning of mammalian genes often correlates with their functional state. For instance, the human cystic fibrosis transmembrane conductance regulator (CFTR) gene associates with the nuclear periphery in its inactive state, bu...
A ChIP-on-chip tiling array approach detects functional histone-free regions associated with boundaries at vertebrate HOX genes [0.03%]
一种针对HOX基因染色体免疫共沉淀芯片阵列的方法可检测出与边界相关的有功能的组蛋白缺失区域
Surabhi Srivastava,Divya Tej Sowpati,Hita Sony Garapati et al.
Surabhi Srivastava et al.
Hox genes impart segment identity to body structures along the anterior-posterior axis and are crucial for proper development. A unique feature of the Hox loci is the collinearity between the gene position within the cluster and its spatial...
Identification of the new gene Zrsr1 to associate with the pluripotency state in induced pluripotent stem cells (iPSCs) using high throughput sequencing technology [0.03%]
利用高通量测序技术鉴定与诱导多能干细胞(iPSCs)的多能性状态相关的新的基因Zrsr1
Shuai Gao,Gang Chang,Jianhui Tian et al.
Shuai Gao et al.
Finding the markers to predict the quality of induced pluripotent stem cells (iPSCs) will accelerate its practical application. The fully pluripotent iPSCs has been determined as viable all-iPSC mice can be generated through tetraploid (4N)...
Identification of deleterious nsSNPs in α, μ, π and θ class of GST family and their influence on protein structure [0.03%]
GST家族α、μ、π和θ类有害nsSNPs的鉴定及其对蛋白质结构的影响
P Yadav,A Chatterjee,A Bhattacharjee
P Yadav
GST family genes have a critical role in xenobiotic metabolism and drug resistance. Among the GST family the GST-μ, GST-π, GST-α and GST-θ are the most abundant classes and have a major role in the carcinogen detoxification process. Nev...
Genome-wide mapping of Painting of fourth on Drosophila melanogaster salivary gland polytene chromosomes [0.03%]
果蝇(Drosophila melanogaster)唾液腺多线染色体Painting of fourth的全基因组绘制
Anna-Mia Johansson,Jan Larsson
Anna-Mia Johansson
The protein Painting of fourth (POF) in Drosophila melanogaster specifically targets and stimulates expression output from the heterochromatic 4th chromosome, thereby representing an autosome specific protein [1,2]. Despite the high specifi...
Genome-wide copy number analysis of cerebrospinal fluid tumor cells and their corresponding archival primary tumors [0.03%]
脑脊液肿瘤细胞及其对应存档原发肿瘤的全基因组拷贝数分析
Mark Jesus M Magbanua,Ritu Roy,Eduardo V Sosa et al.
Mark Jesus M Magbanua et al.
A debilitating complication of breast cancer is the metastatic spread of tumor cells to the leptomeninges or cerebrospinal fluid (CSF). Patients diagnosed with this aggressive clinical syndrome, known as leptomeningeal carcinomatosis, have ...
A definitive haplotype map of structural variations determined by microarray analysis of duplicated haploid genomes [0.03%]
利用芯片分析重复单倍体基因组确定结构变异的精确图谱
Tomoko Tahira,Koji Yahara,Yoji Kukita et al.
Tomoko Tahira et al.
Complete hydatidiform moles (CHMs) are tissues carrying duplicated haploid genomes derived from single sperms, and detecting copy number variations (CNVs) in CHMs is assumed to be sensitive and straightforward methods. We genotyped 108 CHM ...
Jason Blue-Smith
Jason Blue-Smith