From nodule to differentiated thyroid carcinoma: contributions of molecular analysis in 2012 [0.03%]
从结节到分化型甲状腺癌：分子分析在2012年的贡献
Frédérique Albarel,Bernard Conte-Devolx,Charles Oliver
Frédérique Albarel
Today there is a better understanding of the events involved in the initiation and progression of thyroid cancer. It is indeed now known that BRAF and RAS mutations and RET/PTC and PAX8/PPARγ rearrangements account for the majority of mole...
Olivier Devuyst
Olivier Devuyst
Nephrogenic diabetes insipidus (NDI) is caused by an improper response of the kidney to the antidiuretic hormone arginine vasopressin (AVP), leading to a decreased ability to concentrate urine which results in polyuria and polydipsia. The c...
Mini-invasive videoassisted thyroid lobectomy for neonatal hyperfunctioning adenoma related to a somatic TSHr gene mutation [0.03%]
新生儿TSHR基因突变致毒性甲状腺腺瘤的微创视频辅助叶切除术
Erica Stocco,Maria Rosa Pelizzo,Gaia Grassetto et al.
Erica Stocco et al.
We report here a case of a paediatric hyperthyroidism due to a micro-macro-follicular thyroid adenoma in the presence of heterozygous point mutation of TSH receptor (TSHr). We describe the case from the initial diagnosis, through laboratori...
Paul M Stewart,Mark Sherlock
Paul M Stewart
Outcome data from large series confirm increased mortality of patients with pituitary tumours, predominantly due to vascular disease. Control of cortisol secretion and growth hormone (GH) hypersecretion (together with cardiovascular risk fa...
David J Hodson,Patrice Mollard
David J Hodson
The secretion of peptide hormone by the pituitary gland is obligatory for controlling a wide-range of downstream physiological processes. To achieve this, endocrine cells must respond co-ordinately to hypothalamic input to release defined p...
Martin Dupuy,Fabrice Bonneville,Solange Grunenwald et al.
Martin Dupuy et al.
The primary intracranial development of olfactory neuroblastomas, outside olfactory epithelium, is rare. We report a case of primary sellar neuroblastoma without any aggressive histopathological features, managed solely surgically without a...
Intraocular and orbital metastasis as a rare form of clinical presentation of insular thyroid cancer [0.03%]
甲状腺绝缘癌罕见的临床表现——眼内及眶部转移病灶
Tevfik Ozpacaci,Mehmet Mulazimoglu,Muge Oner Tamam et al.
Tevfik Ozpacaci et al.
Insular carcinoma of thyroid is a rare tumor, which accounts for 4 to 6% of thyroid malignancies. Clinically and morphologically it is considered to be in an intermediate position between well-differentiated carcinoma of the thyroid (papill...
Cribriform-morular variant of papillary thyroid carcinoma: characteristic histologic feature of adenomatous polyposis. A case report [0.03%]
滤泡性结肠息肉病的乳头状甲状腺癌筛孔-肌样变型的特征性组织病理学表现及一例报告
Caroline Gronnier,Gianluca Donatini,Emmanuelle Leteurtre et al.
Caroline Gronnier et al.
We report the case of a 24-year-old woman with familial adenomatous polyposis and diagnosed with cribriform-morular variant of papillary thyroid carcinoma. Neck ultrasound and computed tomography identified multiple nodules in the thyroid g...
Hassan Ouleghzal,Caroline Rosales,Marie-Laure Raffin-Sanson
Hassan Ouleghzal
Corticotroph deficiency is a crucial element of anterior pituitary failure requiring careful management. Clinicians should always look for corticotroph deficiency in patients with pituitary disease and also consider the diagnosis in patient...
Dehydroepiandrosterone (DHEA) improves pulmonary hypertension in chronic obstructive pulmonary disease (COPD): a pilot study [0.03%]
脱氢表雄酮(DHEA)可改善慢性阻塞性肺疾病(COPD)相关肺动脉高压：一项初步研究
Eric Dumas de La Roque,Jean-Pierre Savineau,Anne-Cécile Metivier et al.
Eric Dumas de La Roque et al.
Objectives: It was previously shown that dehydroepiandrosterone (DHEA) reverses chronic hypoxia-induced pulmonary hypertension (PH) in rats, but whether DHEA can improve the clinical and hemodynamic status of patients wit...
Clinical Trial
Annales d'endocrinologie. 2012 Feb;73(1):20-5. DOI:10.1016/j.ando.2011.12.005 2012