Andrea Lania,Giovanna Mantovani,Anna Spada
Andrea Lania
The pituitary is the target of different neurohormones that have a crucial role in the control of cell differentiation, cell proliferation and hormone secretion by recognizing specific receptors belonging to the G Protein-Coupled Receptor s...
Philippe Chanson,Peter Kamenický
Philippe Chanson
The ten previous years in terms of acromegaly treatment were essentially characterized by the experience accumulated with new formulations of somatostatin analogues or new drugs such GH-receptor antagonists recently available. Surgery remai...
Frédéric Castinetti,Rachel Reynaud,Alexandru Saveanu et al.
Frédéric Castinetti et al.
Congenital hypopituitarism is a rare disease, usually induced by mutations of genes coding for transcription factors involved in pituitary development. PROP1 mutations represent the first cause of identified congenital hypopituitarism. Curr...
Daniel G Bichet
Daniel G Bichet
Most of the central diabetes insipidus cases seen in general practice are acquired but the rare cases of hereditary autosomal dominant or recessive neurohypophyseal diabetes insipidus have provided further cellular understanding of the mech...
Niki Karavitaki
Niki Karavitaki
Reliable epidemiological data on pituitary adenomas (PAs) are of major importance for estimating the burden on the Health Care System and for designing optimal resource distribution for clinical care and for research activities. Cross-secti...
Long-term control of a MEN1 prolactin secreting pituitary carcinoma after temozolomide treatment [0.03%]
替莫唑胺治疗后长期控制MEN1垂体泌乳素分泌癌的效果
Melanie Philippon,Isabelle Morange,Marilyne Barrie et al.
Melanie Philippon et al.
We report here a rare case of a young male patient presenting with a Multiple Endocrine Neoplasia Type 1 - prolactin-secreting pituitary carcinoma, controlled long-term after temozolomide withdrawal. Initial presentation was pituitary apopl...
[MRI of hypophysitis] [0.03%]
磁共振成像在垂体炎中的应用
Jean-François Bonneville
Jean-François Bonneville
The pattern of adenohypophysitis is that of an enlarged pituitary gland in a normal sized sellar turcica with intense enhancement after gadolinium injection. The pattern of infundibulo-neurohypophysitis is that of a diabetes insipidus, i.e....
Hervé Lefebvre
Hervé Lefebvre
Corticotroph deficiency usually results from exogenous glucocorticoid therapy or, more rarely, from hypothalamopituitary damages. Its diagnostic may be difficult, especially when the deficit in ACTH secretion is partial. Stimulation tests a...
Dominique Maiter,Vanessa Primeau
Dominique Maiter
New information has been provided over the last years regarding treatment of prolactinomas and will be reviewed in this update. Medical treatment with a dopamine agonist (DA) remains the cornerstone of therapy and cabergoline is the first c...
Albert Beckers,Liliya Rostomyan,Adrian F Daly
Albert Beckers
Clinically-relevant pituitary adenomas occur with a prevalence of one case per 1000-1300 of the general population. Although most are sporadic, there are several inherited conditions that incur an increased risk of developing a pituitary ad...