Y chromosome microdeletions and alterations of spermatogenesis, patient approach and genetic counseling [0.03%]
染色体微缺失和精子发生异常的患者处理和遗传咨询
Nathalie Rives
Nathalie Rives
Infertility affects 15% of couples at reproductive age and human male infertility appears frequently idiopathic. The main genetic causes of spermatogenesis defect responsible for non-obstructive azoospermia and severe oligozoospermia are co...
Katrien Stouffs,Sara Seneca,Willy Lissens
Katrien Stouffs
Male infertility, affecting around half of the couples with a problem to get pregnant, is a very heterogeneous condition. Part of patients are having a defect in spermatogenesis of which the underlying causes (including genetic ones) remain...
Célia Ravel,Capucine Hyon,Jean-Pierre Siffroi et al.
Célia Ravel et al.
DAX-1 stands for Dosage sensitive sex-reversal, Adrenal hypoplasia congenital (AHC), on the X chromosome. DAX-1 mutations usually cause primary adrenal insufficiency or congenital adrenal hypoplasia in early childhood and hypogonadotropic h...
Olaf Hiort
Olaf Hiort
Differences or disorders of sex development (DSD) describe a biological discrepancy between chromosomal, gonadal, and phenotypical sex, often affecting the morphology of the genito-reproductive organs. DSD is most often due to genetic abnor...
Peter J O&#x;Shaughnessy,Paul A Fowler
Peter J O&#x;Shaughnessy
Masculinisation and adult fertility in the male are dependent on appropriate fetal endocrine programming. There is also now increasing evidence to indicate that the same mechanisms which regulate masculinisation also affect the general well...
Equol producers can have low leptin levels among prediabetic and diabetic females [0.03%]
雌.equol生产者在前驱糖尿病和糖尿病女性中血清瘦素水平较低
Naoki Sakane,Kazuhiko Kotani,Kokoro Tsuzaki et al.
Naoki Sakane et al.
Objectives: Soy isoflavones have received great attention for their beneficial effects on health and disease, i.e., in patients with diabetes. Equol is a biologically active isoflavone-related metabolite with interindivid...
Comparative Study
Annales d'endocrinologie. 2014 Feb;75(1):25-8. DOI:10.1016/j.ando.2014.01.003 2014
Assessment of serum apelin and lipocalin-2 levels in patients with subclinical hypothyroidism [0.03%]
亚临床甲状腺功能减退患者血清中apo和lipocalin-2水平的评估
Mehmet Zorlu,Muharrem Kiskac,Cumali Karatoprak et al.
Mehmet Zorlu et al.
Objectives: Subclinical hypothyroidism is the precursor to hypothyroidism because it has a tendency to transform into hypothyroidism. Subclinical hypothyroidism is considered one of the risk factors causing metabolic synd...
Lack of association of IRF5 gene polymorphisms with autoimmune thyroid disease: a case-control study. IRF5 gene and AITD [0.03%]
IRF5基因多态性与自身免疫性甲状腺疾病无关：病例对照研究
Fatuma-Said Muhali,Zhen Zhou-jiao,Yuan Wang et al.
Fatuma-Said Muhali et al.
Background: Several studies support a link between autoimmunity and interferon regulatory factor 5 (IRF5) gene polymorphisms. We have taken the opportunity to examine association of the autoimmune disease risk gene, the i...
Comparative Study
Annales d'endocrinologie. 2014 Feb;75(1):19-24. DOI:10.1016/j.ando.2013.12.002 2014
Anti-thyroglobulin antibodies in differentiated thyroid carcinoma patients: Study of the clinical and biological parameters [0.03%]
分化型甲状腺癌患者的抗甲状腺球蛋白抗体的临床及生物学参数研究
Mohammed Nadjib Rahmoun,Ibtissem Bendahmane
Mohammed Nadjib Rahmoun
Objectives: Detection of thyroglobulin in serum is of major clinical importance. The current assay techniques do not have all the qualifications which make the results of thyroglobulin difficult to interpret. The major pr...
Obestatin changes proliferation, differentiation and apoptosis of porcine preadipocytes [0.03%]
OBESTATIN影响猪前脂肪细胞的增殖、分化和凋亡
Shengqiu Tang,Xiaoying Dong,Wei Zhang
Shengqiu Tang
Obestatin, originally identified and purified from rat stomach extracts, was reported to bind to orphan G protein-coupled receptor, GPR39, and inhibit appetite and gastric motility. This study was conducted to investigate the effects of por...