Jean-Louis Wémeau
Jean-Louis Wémeau
Peter Vestergaard
Peter Vestergaard
Calcifications in the kidneys may occur in the parenchyma (nephrocalcinosis), pelvis renis (nephrolithiasis) or ureters (ureterolithiasis). Several factors may protect against stone formation or promote precipitation of stones. Most stones ...
Anya Rothenbuhler,Agnès Linglart
Anya Rothenbuhler
Giovanna Mantovani,Francesca M Elli
Giovanna Mantovani
The term pseudohypoparathryoidism (PHP) refers to a group of rare genetic and epigenetic disorders characterized by resistance to the action of parathyroid hormone (PTH) that activates cAMP signaling in target cells. Together with pseudohyp...
Daniela Betea,Iulia Potorac,Albert Beckers
Daniela Betea
Parathyroid carcinoma is a malignant neoplasm affecting 0.5 to 5.0% of all patients suffering from primary hyperparathyroidism. This cancer continues to cause challenges for diagnosis and treatment because of its rarity, overlapping feature...
Rajesh V Thakker
Rajesh V Thakker
Caroline Silve
Caroline Silve
David P Macfarlane,Ning Yu,Graham P Leese
David P Macfarlane
Primary hyperparathyroidism is common, with epidemiological studies suggesting it may effect up to 1% of the population, and up to 3% of post-menopausal females. Many cases are diagnosed incidentally on routine blood sampling, with the majo...
Jean-Claude Souberbielle,Etienne Cavalier,Catherine Cormier
Jean-Claude Souberbielle
The aim of this article is to discuss the diagnostic approach of an increased serum PTH concentration in a normocalcemic, normophosphatemic patient. Detection of this biological presentation is frequent in routine practice all the more that...
Elizabeth L Monis,Michael Mannstadt
Elizabeth L Monis
Parathyroid hormone (PTH) is the primary regulator of blood calcium levels and bone metabolism. Insufficient levels of PTH lead to hypoparathyroidism, characterized by low serum calcium and elevated serum phosphate levels. It is most common...