Lucie Abouaf,Alain Vighetto,Maud Lebas
Lucie Abouaf
Non-functioning pituitary adenoma may lead to blindness and causes visual impairment in 58% of cases and, more rarely, ocular motor disorder. Patients are slow to become aware of their visual dysfunction, vision in one eye compensating the ...
Non-functioning pituitary adenoma: when and how to operate? What pathologic criteria for typing? [0.03%]
非功能性垂体腺瘤的手术指征、手术方式及病理分型标准是什么？
Frederic Castinetti,Henry Dufour,Stephane Gaillard et al.
Frederic Castinetti et al.
After diagnosis of non-functioning pituitary adenoma and impact assessment (pituitary deficiency, visual field disorder), the question of management arises between surgery and surveillance. This part of the Consensus document aims to clarif...
Are there any causes for increased thyroid volume in women with prolactinoma? [0.03%]
泌乳素瘤女性甲状腺体积增大的原因有哪些？
Berçem Ayçiçek Doğan,Tuğba Taşcı,Ayşe Arduç et al.
Berçem Ayçiçek Doğan et al.
Purpose: The aim of this study was to evaluate thyroid volume in women with prolactinoma and investigate the relationship between anabolic hormones [insulin, insulin like growth factor (IGF-1), estrogen] and thyroid volum...
Françoise Galland,Marie-Christine Vantyghem,Laure Cazabat et al.
Françoise Galland et al.
Prevalence of pituitary incidentaloma is variable: between 1.4% and 27% at autopsy, and between 3.7% and 37% on imaging. Pituitary microincidentalomas (serendipitously discovered adenoma 1cm in diameter) show increased size in 20-24% and 34...
[Paternal GNAS mutations: Which phenotypes? What genetic counseling?] [0.03%]
父系GNAS基因突变：何种临床表现？如何遗传咨询？
Marie-Laure Kottler
Marie-Laure Kottler
Parental imprinting and the type of the genetic alteration play a determinant role in the phenotype expression of GNAS locus associated to pseudohypoparathyroidism (PHP). GNAS locus gives rise to several different messenger RNA transcripts ...
Samuel Boury
Samuel Boury
Neurocognitive outcomes of children secondary to mild iodine deficiency in pregnant women [0.03%]
孕妇轻度碘缺乏对子女神经心理发育的影响研究
Philippe Caron
Philippe Caron
Iodine deficiency is the most important preventable cause of brain damage worldwide. During pregnancy, severe iodine deficiency causes endemic cretinism, whereas mild-to-moderate iodine deficiency impairs neurocognitive function of the offs...
The history of Distilbène® (Diethylstilbestrol) told to grandchildren--the transgenerational effect [0.03%]
迪乙 stilbestrol(Diethylstilbestrol) 的历史告诉子孙—跨世代效应
Patrick Fénichel,Françoise Brucker-Davis,Nicolas Chevalier
Patrick Fénichel
The Distilbène® story is a dramatic episode which belongs to the history of medicine. It provided several useful lessons such as the importance of evidence-based medicine and the hazard to develop treatments during pregnancy without caref...
Etienne Cavalier,Pierre Delanaye,Laurent Nyssen et al.
Etienne Cavalier et al.
Even if the first assay for parathyroid hormone (PTH) was published in the early 1960s, its determination remains a challenge even today. Indeed, in the circulation, PTH is present in its active form (PTH 1-84), but many PTH fragments can a...