Management of Philadelphia chromosome-positive B-cell acute lymphoblastic leukemia in a Jehovah's Witness using chemotherapy free regimen: A case report and review of literature [0.03%]
一例拒绝输血的费城染色体阳性B细胞急性淋巴细胞白血病患者采用无化疗方案治疗:病例报告及文献回顾
Muhammad Hassan Raza,Eiraj Khan,Alexis M Desjarlais et al.
Muhammad Hassan Raza et al.
Introduction and importance: Treatment of Philadelphia chromosome-positive acute lymphoblastic leukemia (pH-positive ALL) in Jehovah's Witness (JW) using chemotherapy agents, opens an ethically and morally challenging par...
Tagraxofusp maintenance post-hematopoietic stem cell transplantation provides long-term survival and manageable safety for a patient with blastic plasmacytoid dendritic cell neoplasm [0.03%]
移植后使用Tagraxofusp维持治疗可使毛细胞白血病相关树突状细胞肿瘤患者长期生存并具有可控安全性
Qaiser Bashir,Marina Konopleva,Glorette Abueg et al.
Qaiser Bashir et al.
Presented here is the case of a 68-year-old woman with blastic plasmacytoid dendritic cell neoplasm (BPDCN) treated with tagraxofusp (TAG) maintenance therapy post-allogeneic hematopoietic stem cell transplantation (allo-HCT). Prior to allo...
Diagnostic and taxonomic challenges in chronic myelomonocytic leukemia with lymph node involvement: A case report and mini-review [0.03%]
慢性粒单细胞白血病伴淋巴结受累的诊断和分类难题:病例报告及综述
Bhaumik Shah,Mitra Abdollahi-Neisani,Pegah Taheri et al.
Bhaumik Shah et al.
The WHO and ICC classifications lack standardized terminology to define the disease phase of chronic myeloproliferative neoplasms in extramedullary sites, particularly lymph nodes, when infiltrates resemble extramedullary hematopoiesis (EH)...
Acute myeloid leukemia: A rare cause of acquired isolated factor VII deficiency [0.03%]
急性髓系白血病所致获得性孤立性凝血因子VII缺乏症
Zaineb Mlayah,Haifa Hafsa,Alaa Ghorbel et al.
Zaineb Mlayah et al.
Background: Acquired factor VII deficiency remains a rare pathology. Only 5 prior reported cases of aFVIID associated with acute myeloid leukemia (AML) have been described in the literature. Despite the rarity of these oc...
Non-coding RNAs: Emerging contributors to chemoresistance in chronic myeloid leukemia [0.03%]
非编码RNA在慢性髓性白血病化疗耐药中的作用机制及其作为治疗靶标的研究进展
Laya Ghadyani Nejhad,Mahsa Sohani,Nasrin Alizad Ghandforoush et al.
Laya Ghadyani Nejhad et al.
Chronic myeloid leukemia (CML), is a myeloproliferative disease characterized by unregulated growth of blood forming cells in bone marrow and blood. The t(9;22)(q34;q11.2) translocation, which results in the formation of a hyperactive tyros...
Impact of PD-1 and PD-L1 expression on treatment outcomes in newly diagnosed acute myeloid leukemia patients [0.03%]
PD-1和PD-L1的表达在新诊断的急性髓系白血病患者中的预后价值研究
Ugur Calis,Merve Aydogan,Guldane Cengiz Seval et al.
Ugur Calis et al.
High expression of immune checkpoint markers may leukemic cells to evade the immune system in AML. This study aimed to investigate the relationship between PD-1/PD-L1 expression and treatment outcomes in AML patients.. The study included 21...
A case report of vanishing bile duct syndrome and diffuse large b cell lymphoma: An uncommon association [0.03%]
一种关于进行性胆管消失综合征合并弥漫大B细胞淋巴瘤的病例报告:一种不常见的关联
Cecilia Anna Fidanza,Ramona Cassin,Francesca Cavallaro et al.
Cecilia Anna Fidanza et al.
We report a rare case of vanishing bile duct syndrome (VBDS) associated with diffuse large B cell lymphoma (DLBCL). VBDS is an uncommon ductopenic disorder associated with various underlying conditions, for which timely treatment is crucial...
AL amyloidosis with elevated peripheral blood cell counts - A frequent association with liver involvement. A single-center retrospective study [0.03%]
外周血细胞计数升高的AL淀粉样变性与肝受累的关系。一项单中心回顾性研究
Mateusz Ziarkiewicz,Justyna Szczygieł,Marta Legatowicz-Koprowska et al.
Mateusz Ziarkiewicz et al.
Background: AL amyloidosis is a systemic protein misfolding disorder characterized by organ deposition of monoclonal immunoglobulin fragments, with insidious onset and progressive course. The plasma cell clone in the bone...
Venetoclax combination with Cladribine, idarubicin, Cytarabine for relapsed T-Cell acute lymphoblastic leukemia/lymphoblastic lymphoma treatment: A case report and literature review [0.03%]
维奈克拉联合克来瑞林、伊达比星和阿糖胞苷治疗复发性T细胞急性淋巴细胞白血病/淋巴瘤的疗效观察:1例报告及文献复习
Alaa Eldein Yahia,Ibrahim Motabi,Abdullah A Alsakkaf et al.
Alaa Eldein Yahia et al.
Acute lymphoblastic leukemia (ALL) represents only 20 % of adult acute leukemias, while Lymphoblastic lymphoma is even rarer, accounting for 2 % of adult non-Hodgkin lymphomas. T-acute lymphoblastic leukemia (T-ALL) and T-lymphoblastic lymp...
Tyrosine kinase inhibitors modulate the expression of peroxiredoxins 1 and 2 in chronic myeloid leukemia cells [0.03%]
酪氨酸激酶抑制剂调节慢性髓性白血病细胞中过氧化氢酶体蛋白1和2的表达
Hiroshi Kazama,Yan-Hua Wang,Junji Tanaka
Hiroshi Kazama
Chronic myeloid leukemia (CML) is characterized by the presence of the BCR::ABL1 fusion protein with active tyrosine kinase activity. The BCR::ABL1 fusion protein induces the production of reactive oxygen species (ROS). DNA damage caused by...