Real-world management of blastic plasmacytoid dendritic cell neoplasm at an academic center with a broad regional referral base [0.03%]
具有广泛区域会诊基础的学术中心在真实世界中对颗粒细胞浆树突状细胞肿瘤的管理
Nathan M Krah,Rasmus Hoeg,Paul J Shami et al.
Nathan M Krah et al.
BPDCN is an aggressive myeloid malignancy characterized by unique expression of CD123, CD4, CD56, CD303, CD304, TCL1 and TCF4. The development of tagraxofusp, a CD123-directed cytotoxin, has revolutionized BPDCN treatment, especially for pa...
The synergistic effect of 2-deoxy-D-glucose and cytarabine on mitochondria of stem-like cells derived from KG1-a [0.03%]
2-脱氧-D-葡萄糖与阿糖胞苷对KG1-a干细胞样细胞线粒体的协同作用效应研究
Sona Rezaei,Mohammad Mohammadzadeh-Vardin,Keyvan Amirshahrokhi et al.
Sona Rezaei et al.
Acute myeloid leukemia (AML) often relapses post-chemotherapy due to leukemia stem cells (LSCs), which rely on mitochondria for energy, ROS regulation, and apoptosis. Targeting mitochondrial pathways may overcome LSC resistance. This study ...
Isolated bone marrow gamma/delta T-cell lymphoma: A difficult case to classify according to the current WHO classification of lymphoid malignancies [0.03%]
孤立性骨髓γδT细胞淋巴瘤-目前WHO淋巴恶性肿瘤分类中一个难以归类的病例
Hideto Hyuuga,Naoki Oishi,Takuma Kumagai et al.
Hideto Hyuuga et al.
Effective treatment of peritoneal myeloid sarcoma with decitabine and venetoclax: A case report [0.03%]
地西他滨和维奈克拉治疗腹膜粒细胞性肉瘤有效：一例报告
Kavya Sudireddy,Minorvi Amin,Rafy Odeh et al.
Kavya Sudireddy et al.
Myeloid sarcomas (MS) are rare extramedullary manifestations of myeloid progenitor cells occurring with or without acute myeloid leukemia. Peritoneal MS is exceptionally uncommon, with no established treatment guidelines, but treatment has ...
Intercurrent presentation of hairy cell leukemia and diffuse large B-cell lymphoma with hemophagocytic lymphohistiocytosis: a case report [0.03%]
毛细胞白血病和弥漫性大B细胞淋巴瘤合并噬血细胞性淋巴组织细胞增多症的病例报告
Tiffany Nong,Xiaoqiong Wang,Wenhui Li et al.
Tiffany Nong et al.
Hairy cell leukemia (HCL) is a rare, indolent B-cell lymphoma that is highly responsive to the purine analog cladribine. A defining feature of classical HCL is the presence of the BRAF V600E mutation, which is almost universally present. Th...
Mechanisms and signaling pathways of tyrosine kinase inhibitor resistance in chronic myeloid leukemia: A comprehensive review [0.03%]
酪氨酸激酶抑制剂耐药的慢性髓性白血病的作用机制及信号转导通路：全面综述
Meriem Lahmouad,Zahrae Rachid,Rawane Bellemrrabet et al.
Meriem Lahmouad et al.
Chronic Myeloid Leukemia (CML) is characterized by aberrant BCR::ABL1 tyrosine kinase activity in hematopoietic stem cells. Although tyrosine kinase inhibitors (TKIs) have revolutionized CML treatment, resistance remains a major clinical ch...
Treatment outcomes and survival analysis of pediatric mature B-Cell non-Hodgkin lymphoma: A retrospective study comparing LMB96 and R-CHOP regimens [0.03%]
LMB96方案与R-CHOP方案治疗儿童成熟B细胞型非霍奇金淋巴瘤疗效和生存分析的回顾性研究
Hamid D Habeeb Rjeib,Usama Al-Jumaily,Inas Muayad Mohammed Ali et al.
Hamid D Habeeb Rjeib et al.
Background: Mature B-cell non-Hodgkin lymphoma (B-NHL) is a prevalent pediatric malignancy with significant treatment advancements. This study retrospectively analyzes clinical characteristics, treatment outcomes, and sur...
Xing Zou,Mengmeng Gu,Yue Su et al.
Xing Zou et al.
Thymic stromal lymphopoietin (TSLP) is a cytokine expressed by various cell types. It is involved in the development of allergies, autoimmune diseases, and cancers. TSLP affects immune responses and disease pathogenesis by binding to a hete...
Baseline erythropoietin level predicts Luspatercept response in Chinese patients with myelodysplastic syndrome: a propensity score-matched analysis [0.03%]
促红素基线水平可预测芦可替尼对中国骨髓增生异常综合症患者的效果：倾向性匹配分析
Doudou Chang,Junyan Zhang,Meiling Zhao et al.
Doudou Chang et al.
Background: Luspatercept is a novel erythroid maturation agent approved for treating transfusion-dependent anemia in myelodysplastic syndrome (MDS). However, predictive biomarkers and real-world data in Asian populations ...
Diagnostic and prognostic relevance of RAF1 gene in acute myeloid leukemia [0.03%]
RAF1基因在急性髓系白血病中的诊断和预后价值研究
Seyedeh Kosar Rahimpour,Yasin Mirazimi,Seyedeh Zahra Shahrokhi et al.
Seyedeh Kosar Rahimpour et al.
Acute Myeloid Leukemia (AML) demands precise diagnostic and prognostic tools for accurate detection and personalized-treatment strategies. Using Real-Time PCR, we investigated the RAF1, miR-146 b-3p, and Circ-RPL15 network expression in AML...