Pediatric-inspired (R3) vs. Adult salvage (FA) chemotherapy in relapsed adolescents and young adults (AYA) acute lymphoblastic leukemia (ALL): A comparative outcome analysis [0.03%]
复发性青少年及年轻成人急性淋巴细胞白血病（AYA ALL）儿科抢救方案(R3)与成人抢救方案（FA）的疗效比较：一项预后分析
Chokri Ben Lamine,Mohammed Alshehri,Lara Samhan et al.
Chokri Ben Lamine et al.
Background: Relapsed acute lymphoblastic leukemia (ALL) in adolescents and young adults (AYA) remains a high-risk scenario with limited evidence guiding optimal salvage regimens. Pediatric-inspired protocols have improved...
Le lymphome cutanée primitif diffus à grandes cellules B : à propos d'un cas Primary cutaneous diffuse large B-cell lymphoma: a case report [0.03%]
原发性皮肤弥漫性大B细胞淋巴瘤1例报告
Mustapha Mechtoune,Fatima Zahra Lahlimi,Illias Tazi et al.
Mustapha Mechtoune et al.
The association of cutaneous B-cell lymphoma and dermatofibrosarcoma is exceptional. We report the case of a 44-year-old patient with a history of Darier-Ferrand dermatofibrosarcoma who presented with cutaneous B-cell lymphoma characterized...
Indolent peripheral T-cell lymphoma resembling Kimura's disease: a new variant of T-cell Lymphoma? [0.03%]
类似Kimura病的惰性外周T细胞淋巴瘤：一种新的T细胞淋巴瘤变异型？
Hui Sun,Jia Feng,Yaping Zhang et al.
Hui Sun et al.
Kimura's disease (KD) is a rare chronic inflammatory disorder of unknown etiology prevalent in middle-aged Asian males. Kimura's disease transforming to T-cell lymphoma or coexisting with T-cell lymphoma have not been reported in the scient...
Asciminib and inotuzumab ozogamicin: a new combination for highly refractory Ph-positive B-cell acute lymphoblastic leukemia [0.03%]
艾斯明联合英夫利西组氨酸盐治疗高难治性费城染色体阳性B细胞急性淋巴细胞白血病的新组合疗法
Aneta Strumilowska,Katherine Devitt,Joanna Conant et al.
Aneta Strumilowska et al.
Management of relapsed acute lymphoblastic leukemia in a patient with down syndrome: A case report [0.03%]
21三体综合征患者复发急性淋巴细胞白血病的治疗——病例报告
Eman Almatar,Sondus Alsharidah,Omnia A Hashem
Eman Almatar
Children with Down syndrome (DS) have a 10-20-fold increased risk of acute lymphoblastic leukemia (ALL) and heightened chemotherapy toxicity. Blinatumomab, a bispecific CD19 × CD3 T-cell engager, offers targeted immunotherapy with reduced ...
Fatal case of disseminated toxoplasmosis following allogeneic stem cell transplantation in Singapore - a case report and review of literature [0.03%]
新加坡造血干细胞移植后继发播散型弓形体病一例及文献复习
Jinghao Nicholas Ngiam,Thuan Tong Tan,Ban Hock Tan et al.
Jinghao Nicholas Ngiam et al.
Toxoplasmosis is a rare but potentially fatal complication post-allogeneic hematopoietic stem cell transplantation (HSCT), often due to latent reactivation. In Singapore, low seroprevalence limits routine screening and prophylaxis. We repor...
First reported TRIB1 copy number loss in myelodysplastic syndrome (MDS) revealed by single nucleotide polymorphism array (SNP-array) with patient-matched control [0.03%]
单核苷酸多态性阵列（SNP-阵列）与患者匹配的对照首次报道肌酐缺失综合征(MDS)中的TRIB1拷贝数丢失
Kun Chi,Lili Song
Kun Chi
A 30-year-old woman with MDS with low blasts (MDS-LB) presented a somatic 67-kb copy number loss at 8q24.13 involving TRIB1, detected by single nucleotide polymorphism (SNP) array. Bone marrow analysis showed no mutations in common MDS gene...
Analysis of atypical clinical manifestations in eight patients with AIDS complicated by lymphoma [0.03%]
八例艾滋病并发淋巴瘤不典型临床表现分析
Peng Fei Tao,Jincheng Lou,Xicheng Wang
Peng Fei Tao
Objective: Acquired Immunodeficiency Syndrome (AIDS)-related lymphoma has diverse clinical manifestations, and its diagnosis is often challenging. Misdiagnosis can delay treatment and affect patient prognosis. We assessed...
Rapid development of Philadelphia chromosome-negative AML in a CML patient with sustained major molecular response to tyrosine kinase inhibitor therapy [0.03%]
费城染色体阴性急性髓系白血病的快速发病：一名CML患者在酪氨酸激酶抑制剂治疗后主要分子学反应持续缓解中的病例报告
Huan Liu,Yunxia Sun,Liangliang Li et al.
Huan Liu et al.
The use of TKIs has significantly improved the prognosis of CML. However, a small subset of patients still experience poor outcomes. We present a rare case of Ph-AML following a diagnosis of CML. The patient achieved CCyR and MMR after 4 mo...
Real-world management of blastic plasmacytoid dendritic cell neoplasm at an academic center with a broad regional referral base [0.03%]
具有广泛区域会诊基础的学术中心在真实世界中对颗粒细胞浆树突状细胞肿瘤的管理
Nathan M Krah,Rasmus Hoeg,Paul J Shami et al.
Nathan M Krah et al.
BPDCN is an aggressive myeloid malignancy characterized by unique expression of CD123, CD4, CD56, CD303, CD304, TCL1 and TCF4. The development of tagraxofusp, a CD123-directed cytotoxin, has revolutionized BPDCN treatment, especially for pa...