Treatment of acute erythroleukemia with Azacitidine: A case series [0.03%]
亚扎胞苷治疗急性红白血病的疗效分析——系列病例报道
Francesca Pierdomenico,Antonio Almeida
Francesca Pierdomenico
Acute erythroleukemia (AEL) is a rare form of acute myeloid leukemia (AML) often associated with a poor prognosis. It is more frequent in elderly patients, limiting the use aggressive therapies. Azacitidine is a hypomethylating agent with r...
Regression of a case of Multiple Myeloma with antiviral treatment in a patient with chronic HCV infection [0.03%]
慢性HCV感染患者中一例多发性骨髓瘤的抗病毒退行性变化
Sara Panfilio,Pasqualina D&#x;Urso,Giorgia Annechini et al.
Sara Panfilio et al.
We report a case of a 54 year old patient with Multiple Myeloma (MM) and chronic HCV infection. In 2005 MM was diagnosed and a chemotherapy was prescribed. Before starting treatment a chronic HCV infection was found. When she came to our In...
Successful treatment with rituximab for angioimmunoblastic T-cell lymphoma [0.03%]
利妥昔单抗治疗血管免疫母细胞性T细胞淋巴瘤成功病例报告
Hidenori Kasahara,Tsunayuki Kakimoto,Hideaki Saito et al.
Hidenori Kasahara et al.
We experienced a patient with angioimmunoblastic T-cell lymphoma (AITL) without Epstein-Barr virus-positive B (EBV-B) cells at initial presentation who progressed to AITL with expansion of EBV-B cells at relapse. Based on the results of rep...
The use of low-dose protracted oral clofarabine in a patient with myelodysplastic syndrome after failing 5-azacitidine [0.03%]
克拉克菌素小剂量口服长疗程治疗接受地西他滨治疗失败的骨髓增生异常综合征患者
Omar Al Ustwani,Jessica D Greene,Meir Wetzler
Omar Al Ustwani
Patients with myelodysplastic syndrome who fail hypomethylating agents have a very short median survival and about 25% risk of disease transformation to acute myeloid leukemia. We report our experience with low-dose protracted oral clofarab...
Large granular lymphocytic leukemia associated with Lambert-Eaton Myasthenic Syndrome: A case report [0.03%]
与兰伯特-伊顿肌无力综合征相关的大型颗粒淋巴细胞白血病的病例报告
Richard Lemal,Carine Chaleteix,Patrice Minard et al.
Richard Lemal et al.
Large granular lymphocytic (LGL) leukemia is an uncommon clonal lymphoproliferative disorder. Lambert-Eaton Myasthenic Syndrome (LEMS) is a rare neuromuscular autoimmune disease caused by pathogenic autoantibodies targeting the voltage-gate...
A successful renal transplantation for renal failure after dasatinib-induced thrombotic thrombocytopenic purpura in a patient with imatinib-resistant chronic myelogenous leukaemia on nilotinib [0.03%]
尼洛替尼治疗耐药性格鲁布氏慢性粒细胞性白血病继发达沙替尼诱导的溶血性尿毒症综合征后成功进行肾移植术一例报告
Suella Martino,Etienne Daguindau,Christophe Ferrand et al.
Suella Martino et al.
Second-generation tyrosine kinase inhibitors (TKI2) often induce molecular remission, and prolonged survival with a better tolerance in imatinib-resistant chronic myelogenous leukaemia (CML) patients. We report the case of a CML in first ch...
Evaluation of early discharge after hospital treatment of neutropenic fever in acute myeloid leukemia (AML) [0.03%]
急性髓系白血病患者医院治疗粒细胞缺乏症发热后的早期出院评估
Victor Chow,Kathleen Shannon Dorcy,Ravinder Sandhu et al.
Victor Chow et al.
Background: Hospital admission for neutropenic fever in patients with AML is a standard practice. However, discharge practices vary once patients become afebrile, with many patients hospitalized until rise in the absolute...
GATA2 zinc finger 2 mutation found in acute myeloid leukemia impairs myeloid differentiation [0.03%]
急性髓系白血病中的GATA2锌指突变影响髓样分化
Keiko Niimi,Hitoshi Kiyoi,Yuichi Ishikawa et al.
Keiko Niimi et al.
We identified two novel GATA2 mutations in acute myeloid leukemia (AML). One mutation (p.R308P-GATA2) was a R308P substitution within the zinc finger (ZF)-1 domain, and the other (p.A350_N351ins8-GATA2) was an eight-amino-acid insertion bet...
Two copies of isochromosome 5p in refractory cytopenia with multilineage dysplasia: A case report [0.03%]
难治性血细胞发育异常性细胞减少症候群并两条5号染色体短臂等臂染色体病例报告
Carolina Giudici,Riccardo Lingeri,Carlo Patriarca et al.
Carolina Giudici et al.
Isochromosome 5p-i(5)(p10)-represents a rare but recurrent abnormality in myeloid disorders, especially in acute myeloid leukemia. In all published cases, the isochromosome 5p was present in single copy and accompanied by one or more additi...
Durable second complete remissions with oral melphalan in hypocellular Acute Myeloid Leukemia and Refractory Anemia with Excess Blast with normal karyotype relapsing after intensive chemotherapy [0.03%]
口服马法兰治疗正常核型细胞减少性急性髓系白血病和难治性幼淋巴细胞性贫血复发后的第二完全缓解期疗效持久
Annika M Whittle,Sylvia Feyler,David T Bowen
Annika M Whittle
We treated six patients who had relapsed after intensive chemotherapy, presenting initially with AML or RAEB, a hypocellular marrow and normal karyotype, and who were deemed unsuitable for re-induction with intensive chemotherapy, with low ...