Hematologic improvements in a myelodysplastic syndromes with myelofibrosis (MDS-F) patient treated with azacitidine [0.03%]
芦可替尼治疗骨髓纤维化患者的血液学改善及相关并发症的处理经验总结
Daisuke Okamura,Akira Matsuda,Maho Ishikawa et al.
Daisuke Okamura et al.
Myelodysplastic syndromes with myelofibrosis (MDS-F) is a poor prognostic hematopoietic disorder. Azacitidine was shown to prolong survival of high-risk MDS patients. However, the effects of azacitidine on MDS-F have yet to be elucidated. A...
Ricardo García-Muñoz,Susana Rubio-Mediavilla,Diego Robles-de-Castro et al.
Ricardo García-Muñoz et al.
Intravascular large B cell lymphoma (IVBCL) is a rare type of extranodal large B cell lymphoma characterized by selective growth of lymphoma cells within the microvasculature. We present an illustrative case of intravascular B cell lymphoma...
Relationship between baseline white blood cell count and renal and hepatic function in older patients with acute myeloid leukemia [0.03%]
老年急性髓系白血病患者基础白细胞计数与肾功能、肝功能的关系
Jacques Delaunay,Grzegorz Mazur,Mark Minden et al.
Jacques Delaunay et al.
Background: In a phase III trial, older patients with acute myeloid leukemia (N=485) received decitabine or treatment choice (supportive care or cytarabine). This post hoc analysis examined whether baseline renal and hepa...
Acute renal failure and normal blood count: A rare presentation of T-cell acute lymphoblastic leukemia [0.03%]
急性肾功能衰竭和正常血常规：T细胞急性淋巴细胞白血病的罕见表现形式
Peter H Asdahl,Linda F Warner,Knud Bendix et al.
Peter H Asdahl et al.
A 10-year-old boy presented with headache and visual disturbance. During work-up in hospital he developed acute renal failure with a maximum creatinine level of 534 μmol/l. Complete blood count was normal. Kidney and bone marrow biopsy bot...
FLAG-induced remission in a patient with acute mast cell leukemia (MCL) exhibiting t(7;10)(q22;q26) and KIT D816H [0.03%]
FLAG诱导的急性mast细胞白血病（MCL）患者缓解，该患者的MCL带有t（7;10）（q22;q26）和KIT D816H突变
Peter Valent,Katharina Blatt,Gregor Eisenwort et al.
Peter Valent et al.
Mast cell leukemia (MCL) is a life-threatening disease associated with high mortality and drug-resistance. Only few patients survive more than 12 months. We report on a 55-year-old female patient with acute MCL diagnosed in May 2012. The di...
Extreme hyperleukocytosis in a pediatric T-ALL patient with a rare translocation, t(7;19)(q35;p13), and submicroscopic deletions at 4q25, 7q33 and 10q23 [0.03%]
一例罕见易位t(7;19)(q35;p13)伴4q25、7q33和10q23亚微缺失的儿童T-ALL极高白血病细胞计数患者的报告
Christopher Veigaard,Anni Aggerholm,Henrik Hasle et al.
Christopher Veigaard et al.
Although childhood T-cell acute lymphoblastic leukemia (T-ALL) is a high-risk disease the outcome can vary considerably. The varying outcomes suggest that unrecognized factors may contribute to disease progression. We report on a 2-year-old...
Prevalence of human endogenous retroviral element associates with Hodgkin's lymphoma incidence rates [0.03%]
人内源性逆转录病毒元件的流行率与霍奇金淋巴瘤发病率有关
Wee Hong Woo,Liang Shen,Sai Mun Leong et al.
Wee Hong Woo et al.
Human endogenous retrovirus-H (HERV-H) is implicated in leukaemias and lymphomas, but the precise molecular mechanism underlying HERV-mediated carcinogenesis remains unknown. We determined the prevalence of HERV-H in a cross-section of the ...
Haemoglobinopathia Ypsilanti - A rare, but important differential diagnosis to polycythaemia vera [0.03%]
伊普西兰蒂血红蛋白病-一种罕见但重要的真性红细胞增多症鉴别诊断
Marietta Nygaard,Jesper Petersen,Ole W Bjerrum
Marietta Nygaard
We present a case of a mother and daughter who were initially diagnosed with polycythaemia vera and treated with venesectio. As JAK2 V6217F/exon 12 mutation analyses became available, these were performed and turned out negative. Haemoglobi...
Rabbit antithymocyte globulin induces rapid expansion of effector memory CD8 T cells without accelerating acute graft versus host disease [0.03%]
兔抗胸腺细胞球蛋白诱导效应记忆CD8 T细胞的快速扩增而不加速急性移植物抗宿主病
Friedrich Wittenbecher,Kathrin Rieger,Mikalai Dziubianau et al.
Friedrich Wittenbecher et al.
Rabbit antithymocyte globulin (Thymoglobulin(®)) is commonly used as graft-versus-host disease (GvHD) prophylaxis. Since we found similar total CD8 T cell numbers in patients with and without Thymoglobulin(®) therapy within the first six ...
Differential cytogenetic profile in advanced chronic myeloid leukemia with sequential lymphoblastic and myeloblastic blast crisis [0.03%]
慢性粒细胞白血病急淋变和急非淋变的染色体差异分析
C Calderón-Cabrera,I Montero,R M Morales et al.
C Calderón-Cabrera et al.
Frequency of additional chromosomal abnormalities in chronic myeloid leukemia (CML) is estimated to be 7% in chronic phase and increases to 40-70% in advanced disease. Progression of CML from chronic phase to accelerated phase or blast cris...