On arsenic trioxide in the clinical treatment of acute promyelocytic leukemia [0.03%]
三氧化二砷在急性早幼粒细胞白血病临床治疗中的应用
Peng Zhang
Peng Zhang
Arsenic is generally considered hypertoxic. However, it has been used in traditional Chinese medicine since ancient times, to treat serious illnesses. Recently, a single dose of arsenic trioxide (As2O3) has been found especially effective i...
Aspirin and risk of multiple myeloma in adults: A systematic review and meta-analysis [0.03%]
阿司匹林与成人患多发性骨髓瘤风险的关联：系统评价和.meta.分析
Shing Fung Lee,Ting Ying Ng,Frank Chi Sing Wong et al.
Shing Fung Lee et al.
Multiple myeloma is a relatively uncommon plasma cell malignancy. Preclinical and clinical studies have suggested that aspirin might modify the risk of multiple myeloma. We performed a systematic review and meta-analysis of studies to exami...
A rare breed: Wild-type braf and ighv expression in a 29 year old lady with classical hairy cell leukemia [0.03%]
罕见病例报道：年轻经典型毛细胞白血病女性患者具有野生BRAF和IGHV表型
Aneesha Hossain,Hind Rafei,Amar Jariwala et al.
Aneesha Hossain et al.
The V600 BRAF mutation has been described as a key mutation in the pathogenesis of classical hairy cell leukemia (c-HCL) cases without expression of a mutant immunoglobulin heavy chain (IgHV). Here we present a rare case of c-HCL with neith...
A case of acute myeloid leukemia with e6a2 BCR-ABL fusion transcript acquired after progressing from chronic myelomonocytic leukemia [0.03%]
一例由慢性粒单细胞白血病进展而来的E6A2 BCR-ABL融合转录本急性髓系白血病病例报告
Jinjuan Yao,Dan Douer,Lu Wang et al.
Jinjuan Yao et al.
Philadelphia (Ph) chromosome is a cytogenetic hallmark of chronic myeloid leukemia (CML). Most patients with CML harbor either the e13a2 or e14a2 BCR-ABL fusion product, while a small subset of the cases expresses e1a2 or e19a2 transcripts....
Sarah M Hayes,Justin A Wasko,Erica Dahl Warlick
Sarah M Hayes
We describe a relapsed AML patient who had two prior severe reactions to clofarabine involving rigors, emesis, tachycardia, hypotension, and acute kidney injury. Given previous prolonged remission achieved with clofarabine and cytarabine th...
"Hemophagocytic Lymphohistiocytosis after EBV reactivation and ibrutinib treatment in relapsed/refractory Chronic Lymphocytic Leukemia" [0.03%]
爱布拉激活和伊布替尼治疗后慢性淋巴细胞白血病复发/难治患者的噬血细胞性淋巴组织细胞增多症病例报告
Maurizio Cavallari,Maria Ciccone,Simonetta Falzoni et al.
Maurizio Cavallari et al.
Hemophagocytic Lymphohistiocytosis (HLH) is a rare syndrome characterized by ineffective T-cell and NK response. We report the clinical course of a patient with relapsed CLL who developed acute symptoms soon after starting ibrutinib. Hyperp...
Clinical outcomes of AML patients treated with Azacitidine in Portugal: A retrospective multicenter study [0.03%]
阿扎胞苷治疗葡萄牙AML患者的临床结局：一项回顾性多中心研究
António Almeida,Ana Rita Ferreira,Maria João Costa et al.
António Almeida et al.
Retrospective data was collected from 77 elderly acute myeloid leukemia (AML) patients treated with Azacitidine (AZA) and 50 elderly AML patients treated with intensive chemotherapy (IC) from 4 Portuguese Hospitals. Median OS was 10.6 month...
A primary esophageal MALT lymphoma patient with Helicobacter pylori infection achieved complete remission after H. pylori eradication without anti-lymphoma treatment [0.03%]
一名原发性胃食管黏膜相关淋巴组织边缘区淋巴瘤患者根除幽门螺旋杆菌后达到完全缓解
Keiichi Moriya,Hideto Tamura,Kyoko Nakamura et al.
Keiichi Moriya et al.
Primary esophageal lymphoma is an extremely rare disease. We report a 76-year-old woman with esophageal lymphoma who achieved remission after Helicobacter pylori (HP) eradication. Esophagogastroduodenoscopy (EGD) revealed a mass in the lowe...
Irfan Yavasoglu,Gokhan Sargin
Irfan Yavasoglu
The role of the Exon 13 G571S JAK2 mutation in myeloproliferative neoplasms [0.03%]
jak2 exon 13 g571s突变在髓系肿瘤中的作用
Burak Bahar,Kevin Barton,Ameet R Kini
Burak Bahar
The exon 14 JAK2 V617F mutation has been well established as a driver mutation in polycythemia vera (PV) and other myeloproliferative neoplasms. JAK2 exon 12 mutations have also been implicated in PV, although patients with these mutations ...