The rare translocation t(14;21)(q11;q22) detected in a Moroccan patient with T-cell acute lymphoblastic leukemia [0.03%]
一名Moroccan T细胞急性淋巴细胞白血病患者的罕见易位t(14;21)(q11;q22)被检测出
Z Takki Chebihi,A Belkhayat,E Chadli et al.
Z Takki Chebihi et al.
Cytogenetic studies of acute lymphoblastic leukemia have been at the forefront of research in the pathogenesis of cancer. The presence of recurring chromosomal abnormalities (either numeral or structural rearrangements) provides immediate c...
High-dose methotrexate vs. Capizzi methotrexate for the treatment of childhood T-cell acute lymphoblastic leukemia [0.03%]
大剂量甲氨蝶呤与Capizzi方案甲氨喋吟治疗儿童T细胞急性淋巴细胞白血病的比较研究
Wasil Jastaniah,Naglla Elimam,Khalid Abdalla et al.
Wasil Jastaniah et al.
Sixty-three children (1-14 years of age) newly diagnosed with T-cell acute lymphoblastic leukemia were treated from January 2001 to December 2014. Patient outcomes were evaluated based on the regimen received; Capizzi methotrexate (C-MTX) v...
Renal infiltration presenting as acute kidney injury in Hodgkin lymphoma - A case report and review of the literature [0.03%]
以急性肾损伤形式出现的霍奇金淋巴瘤肾脏浸润一例报告及文献复习
Wellington Fernandes da Silva Junior,Laila Lopes de Farias Pinho,Cássio Lins Gil de Farias et al.
Wellington Fernandes da Silva Junior et al.
Renal involvement in Hodgkin lymphoma (HL) is rare, although extralymphatic disease is usually found. Acute kidney injury is a recognized presentation of non-Hodgkin lymphoma, with bilateral kidney involvement, promptly requiring specific t...
Lenalidomide induced durable remission in a patient with MDS/MPN-with ring sideroblasts and thrombocytosis with associated 5q- syndrome [0.03%]
来那度胺诱导了伴有5q-综合症的MDS/MPN-环形铁粒幼细胞性贫血和血小板增多症患者持久缓解
Ahmed Alshaban,Osvaldo Padilla,Alexander Philipovskiy et al.
Ahmed Alshaban et al.
We describe a patient with MDS/MPN with ring sideroblasts and thrombocytosis who had deletions of long arm of chromosome 5 (5q-) and chromosome 20 (20q-). Molecular studies showed an exon 9, frame shift mutation in the calreticulin (CALR) g...
The role of FLT3 inhibitors as maintenance therapy following hematopoietic stem cell transplant [0.03%]
FLT3抑制剂在造血干细胞移植后的维持治疗中的作用
Grace Xiuqing Li,Lan Wang,Bassam Yaghmour et al.
Grace Xiuqing Li et al.
Activating mutations in FLT3 in acute myeloid leukemia (AML) portend a poor prognosis, and targeting FLT3 with a tyrosine kinase inhibitor has been an area of intense research recently. Most FLT3 mutated AML patients undergo hematopoietic s...
Detection of KIT mutations in core binding factor acute myeloid leukemia [0.03%]
核心结合因子急性髓系白血病中KIT突变的检出率研究
Passant Badr,Ghada M Elsayed,Dalia Negm Eldin et al.
Passant Badr et al.
We have investigated the frequency and the effect of KIT mutations on the outcome of patients with CBF-AML. 69 patients (34 pediatrics and 35 adults) with CBF-AML were enrolled in the study. The frequency of KIT mutations was higher in adul...
All- trans-retinoic-acid and arsenic trioxide induced remission in promyelocytic blast crisis [0.03%]
全反式维甲酸和砷剂诱导的急性早幼粒细胞白血病治疗完全缓解
Teresa A Colvin,Pankit Vachhani,Sheila Sait et al.
Teresa A Colvin et al.
A 78-year-old-male with chronic myeloid leukemia (CML) treated for seven years with dasatinib developed an acute promyelocytic leukemia complicated by disseminated intravascular coagulopathy. A promyelocytic blast crisis was diagnosed by de...
Retrospective analysis of primary plasma cell leukemia in Kansai Myeloma Forum registry [0.03%]
kansai myeloma论坛注册表中初始浆细胞白血病的回顾性分析
Aya Nakaya,Hideo Yagi,Hitomi Kaneko et al.
Aya Nakaya et al.
We retrospectively analyzed twenty-six patients with primary plasma cell leukemia (pPCL) registered from May 2005 until April 2015 by the Kansai Myeloma Forum. Twenty patients received novel agents (bortezomib or lenalidomide), and their me...
Secondary pure red cell aplasia in multiple myeloma treated with lenalidomide [0.03%]
来那度胺治疗多发性骨髓瘤继发红细胞纯系发育不良の一例报告
Tomoki Ito,Aya Nakaya,Shinya Fujita et al.
Tomoki Ito et al.
Pure red cell aplasia (PRCA) is a rare disorder characterized by marked erythroid hypoplasia with maturation arrest in the bone marrow. Secondary acquired PRCA may be associated with hematologic disorders. A few case reports have described ...
Tumor necrosis factor- and interleukin-6-producing high-grade B-cell lymphoma, not otherwise specified in the pleura [0.03%]
胸膜原发肿瘤坏死因子和白细胞介素-6产生的高级别B细胞淋巴瘤
Shoko Nakayama,Mitsuhiro Matsuda,Tatsuya Adachi et al.
Shoko Nakayama et al.
A 65-year-old man was admitted to our hospital with left-sided chest and back pain and dyspnea. Computed tomography demonstrated a marked circumferential left pleural thickening. A thoracoscopic pleural biopsy led to a diagnosis of high-gra...