Clonal evolution revealed by next-generation sequencing in a long-term follow-up patient with hypereosinophilia [0.03%]
二代测序技术揭示的长期随访低增生性高嗜酸细胞综合症患者的克隆演化过程
Meiyu Chen,Jie Liu,Wei Qin et al.
Meiyu Chen et al.
The natural history of primary hypereosinophilia remains poorly defined, given the underlying disease heterogeneity. Recently, targeted NGS helps to establish clonality in a subset of patients with hypereosinophilia. We first reported the c...
Effective maintenance treatment with lenalidomide for a patient with aggressive adult T cell leukemia after chemotherapy [0.03%]
利奈唑胺对成人T细胞白血病/淋巴瘤维持治疗的有效性评估
Satoko Oka,Kazuo Ono,Masaharu Nohgawa
Satoko Oka
Adult T cell leukemia/lymphoma (ATL) is incurable with conventional chemotherapies, and allogeneic stem cell transplantation (SCT) is the only curative treatment. Direct antitumor effects and antitumor immune responses are important factors...
Potentially important miRNAs in enteropathy-associated T-cell lymphoma pathogenesis: A pilot study [0.03%]
与肠道病相关T细胞淋巴瘤发病机制的重要微小核糖核酸的鉴定：一项初步研究
Lindsey Clarke,Raju Sr Adduri,Paul Smyth et al.
Lindsey Clarke et al.
Matched unrelated donor hematopoietic progenitor cell transplantation: A report based on a single registry in India [0.03%]
印度单中心骨髓库匹配无关供者造血干细胞移植报告
Aseem K Tiwari,Vikash Chandra Mishra,Apeksha Tiwari et al.
Aseem K Tiwari et al.
Introduction: Currently, more than 10,000 matched unrelated donor transplants (MUDT) are performed annually worldwide. India has recorded a significant increase in the number of hematopoietic progenitor cell transplantati...
Chronic myelomonocytic leukemia as a transformation from polycythemia vera [0.03%]
真性红细胞增多症向慢性粒单细胞白血病转化
Mirela Andrei,Anita Pandey,Boris Avezbakiyev et al.
Mirela Andrei et al.
The hallmark of Polycythemia vera (PV) is the presence of JAK2V617F mutation and increased RBC mass. Chronic myelomonocytic leukemia (CMML) is defined as persistent blood absolute monocyte count (AMC) >/= 1 × 109/L for at least 3 months wi...
Evaluation of eltrombopag in patients with aplastic anemia in real-world experience [0.03%]
艾曲波帕治疗再生障碍性贫血真实世界经验评估
Akiko Konishi,Aya Nakaya,Shinya Fujita et al.
Akiko Konishi et al.
Background: Although eltrombopag has recently been approved for treating AA, the effects of its clinical use remain unknown. Methods: W...
Myodesopsia is a symptom of central nervous system blast crisis in chronic myeloid leukemia [0.03%]
视网膜症状可能是慢性粒细胞性白血病中枢神经系统急变的症状
Kazuyoshi Ishii,Aya Nakaya,Shinya Fujita et al.
Kazuyoshi Ishii et al.
A 49-year-old woman diagnosed with chronic myeloid leukemia in the chronic phase was started on dasatinib treatment, after which she complained of myodesopsia. Nineteen months after diagnosis, the patient again complained of myodesopsia and...
Clinical characteristics and treatment outcome of patients with isochromosome 17q (i17q) abnormality and myeloid neoplasms: A single center experience [0.03%]
17号染色体等臂染色体(i(17q))异常的髓系肿瘤患者的临床特征及治疗结局：单中心经验报道
Siddhartha Ganguly,Mason Uvodich,Ajoy Dias et al.
Siddhartha Ganguly et al.
Primary isolated bone marrow diffuse large B cell lymphoma with long-term complete remission [0.03%]
初治孤立骨髓弥漫大B细胞淋巴瘤长期内存阴性缓解1例报告
Hiroko Nishida,Hiroshi Suzuki,Masao Hori et al.
Hiroko Nishida et al.
Secondary bone marrow involvement of non-Hodgkin's lymphoma (NHL) is relatively common. However, primary isolated bone marrow involvement in NHL which was successfully treated and remains in complete remission (CR) for a long-term duration ...
Cytomegalovirus reactivation triggers the late onset of hyperthyroidism after autologous peripheral blood transplantation [0.03%]
自体外周血干细胞移植后巨细胞病毒再活化触发晚期甲状腺功能亢进发病
Satoko Oka,Kazuo Ono,Masaharu Nohgawa
Satoko Oka
Thyroid dysfunction is an important issue in patients receiving autologous and allogenic hematopoietic stem cell transplantation (HSCT). However, the exact mechanisms underlying thyrotoxicosis secondary to HSCT remain unclear. The present c...